| Gene Name | WASF1 |
|
| Specie | Homo sapiens | |
| Full Name | WASP family member 1 | |
| Also known as | NEDALVS|SCAR1|WAVE|WAVE1 | |
| Coordinate | chr6:110099819-110179670 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| WASF1P1 | chr2:108277015-108277411 | + |
Intergenic |
ENSG00000227597 | UCSC |
| >NM_001024934.2 |
| AGCTCGCGGTGTTGTTCACTCGCGCGTCGAGCACACGGTGGGTCCGGCGGCGGGTTGGCGCCCCAGGCGGCGTTCCCTGTGGCCTGGCGCCTGGGCCGCTGCCCTGAGCGGGTTCCGCCCCAGAGCCCGACCCTCCTGGGGGCTCTAGGCGGAGTCCCGCGAGCCGAGGGGGACCGGCGACCGCTGCCGAAGCATGAAGAAGGGGTAAGGCGTGAGCCCCCAAGATTTCACGCATGCCCCCTAGCTTCGGTACTCTGACACCTTCTCTTGCACTTGCGGATGATGAACTGGAATAACGATGAAAGAAAGCACATCCGATCTCAACATTCACGTCCTGCCCTATAACCGATTAATTAATTGATCCCCAGCTAGACTAGGTGAACTGGCACAAAGGTTAATCTCAAGATGCCGCTAGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCACACAGCACTGCCTAGAGGCATTAAGAATGAACTGGAATGTGTAACCAATATTTCCTTGGCAAATATAATTAGACAACTAAGTAGCCTAAGTAAATATGCTGAAGATATATTTGGAGAATTATTCAATGAAGCACATAGTTTTTCCTTCAGAGTCAACTCATTGCAAGAACGTGTGGACCGTTTATCTGTTAGTGTTACACAGCTTGATCCAAAGGAAGAAGAATTGTCTTTGCAAGATATAACAATGAGGAAAGCTTTCCGAAGTTCTACAATTCAAGACCAGCAGCTTTTCGATCGCAAGACTTTGCCTATTCCATTACAGGAGACGTACGATGTTTGTGAACAGCCTCCACCTCTCAATATACTCACTCCTTATAGAGATGATGGTAAAGAAGGTCTGAAGTTTTATACCAATCCTTCGTATTTCTTTGATCTATGGAAAGAAAAAATGTTGCAAGATACAGAGGATAAGAGGAAGGAAAAGAGGAAGCAGAAGCAGAAAAATCTAGATCGTCCTCATGAACCAGAAAAAGTGCCAAGAGCACCTCATGACAGGCGGCGAGAATGGCAGAAGCTGGCCCAAGGTCCAGAGCTGGCTGAAGATGATGCTAATCTCTTACATAAGCATATTGAAGTTGCTAATGGCCCAGCCTCTCATTTTGAAACAAGACCTCAGACATACGTGGATCATATGGATGGATCTTACTCACTTTCTGCCTTGCCATTTAGTCAGATGAGTGAGCTTCTGACTAGAGCTGAGGAAAGGGTATTAGTCAGACCACATGAACCACCTCCACCTCCACCAATGCATGGAGCAGGAGATGCAAAACCGATACCCACCTGTATCAGTTCTGCTACAGGTTTGATAGAAAATCGCCCTCAGTCACCAGCTACAGGCAGAACACCTGTGTTTGTGAGCCCCACTCCCCCACCTCCTCCACCACCTCTTCCATCTGCCTTGTCAACTTCCTCATTAAGAGCTTCAATGACTTCAACTcctccccctccagtacctcccccacctccacctccagccactgctttgcaagctccagcagtaccaccacctccagctccTCTTCAGATTGCCCCTGGAGTTCTTCACCCAGCTCCTCCTCCAATTGCACCTCCTCTAGTACAGCCCTCTCCACCAGTAGCTAGAGCTGCCCCAGTATGTGAGACTGTACCAGTTCATCCACTCCCACAAGGTGAAGTTCAGGGGCTGCCTCCACCCCCACCACCGCCTCCTCTGCCTCCACCTGGCATTCGACCATCATCACCTGTCACAGTTACAGCTCTTGCTCATCCTCCCTCTGGGCTACATCCAACTCCATCTACTGCCCCAGGTCCCCATGTTCCATTAATGCCTCCATCTCCTCCATCACAAGTTATACCTGCTTCTGAGCCAAAGCGCCATCCATCAACCCTACCTGTAATCAGTGATGCCAGGAGTGTGCTACTGGAAGCAATACGAAAAGGTATTCAGCTACGCAAAGTAGAAGAGCAGCGTGAACAGGAAGCTAAGCATGAACGCATTGAAAACGATGTTGCCACCATCCTGTCTCGCCGTATTGCTGTTGAATATAGTGATTCGGAAGATGATTCAGAATTTGATGAAGTAGATTGGTTGGAGTAAGAAAAATGCATTGATAAATATTACAAAACTGAATGCAAATGTCCTTTGTGGTGCTTGTTCCTTGAAAATGTTTGGTCATTCTAGTGTTTTGCTTTCTTTTCCTTATAATAAATGACCCTTTTCCTCCATAACTTTTGATTTCTAAGGAAAATATTAGCATACATTTCAAACTAAATGTTTTACAGTGGCTTATCTTTTTTTTCCCCCTGAAAAGACTAATTTGGTCAAATAAACCACTAAGTATTAAGCATGGACAGCTGTTGTTAGAGTAGCAGATTCAGTTTTTTGATATATCTTAATTGTGTACTTTGTGAATTTTAATTTAAAGAAAGCAACTGAAATTGAAATCTTGAGGGCAGCTGTGTCTACTAATGAGCCTTATTCCATTTCCTGATGTTTTAAAAGAAGAAACACTGCCTTGATTATACGAATACACTCAGAAAGTACATTTAGCTTGTAGTGTTGAATTCTCTTAAAGGAATGCTTGAATTTTTTCATTATTGTTTTATTGTTTTTATATACTTGCCTTATTTGAATGTTTAGCAGTATCCCCTTCCCACTTATATATTGTGTGATATGATTTTGCTTGCCTATAGGAGTTAAAAACTTTTCCATGTGAAATACTCTGACTTAAACATACATGTAACTTACATAACTGTTAAGAATAACAGTCTGATTTAATAAATGGTTCATTTTAAAAGTT |