| Gene Name | LRRFIP2 |
|
| Specie | Homo sapiens | |
| Full Name | LRR binding FLII interacting protein 2 | |
| Also known as | HUFI-2 | |
| Coordinate | chr3:37052626-37176817 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| LRRFIP2P1 | chrX:73237529-73238720 | - |
Intergenic |
ENSG00000237014 | UCSC |
| >NM_017724.2 |
| GTCGTCGACCCTGTGGCCCCGCCCATCCTTCGCCTCCTCAGTCGGCCGCTCAGGCTGCGGCTCCTCCCGGGGCCGGTTCCCGCTGTCTCAGCCGCGGCGCAGAGGGCACATCGGCCTGACCGACTAGCCGGCTGCCAGTGCCGGGAGCCGCCGCGTCCATCCCCGCCCGCCTGGCCGGGGACCCAGGACTGAGTCGTCCAGCTGCGCCCCTCGCCCATAGCCCCAGCGGGCGCCGGGCGGGCGAGCAGCTCTTCGGCCCTTCCCGGACAGCGACGCAGTCGCAGCGCGCGCCCTAACACAGATGTGGGAAGATAAATGAAGGGGTCTAGATGTAAATGTCAGTGGAAAGGAGAGCTACCATCACTAAGGGCTGAAAACACAGTTAAATCACTTTCAAAGTTAAAAGACTATTAAGAACACAAGATGGGGACTCCTGCTTCTGGAAGGAAAAGAACACCTGTGAAAGACCGATTTTCTGCAGAAGATGAAGCTTTGAGTAACATTGCCAGAGAGGCAGAGGCAAGGCTGGCAGCAAAACGGGCTGCCCGGGCAGAAGCAAGAGATATACGCATGAGAGAACTGGAACGACAACAAAAAGAGTTGGATGAAAAATCTGACAAACAGTATGCTGAAAATTATACAAGACCTTCATCTCGAAATTCTGCCTCAGCAACAACCCCTCTAAGTGGAAACTCATCCAGACGAGGAAGTGGGGACACCAGCAGCTTAATAGATCCAGACACTTCATTAAGTGAATTGCGGGAATCTTTGTCTGAAGTGGAAGAAAAATACAAGAAAGCCATGGTTTCCAATGCACAGTTAGACAATGAGAAGAACAATTTGATCTACCAAGTAGACACACTCAAGGATGTTATTGAAGAGCAGGAGGAACAGATGGCAGAATTTTATAGAGAAAATGAAGAAAAATCAAAGGAGTTAGAAAGGCAGAAACATATGTGTAGTGTGCTGCAGCATAAGATGGAAGAACTTAAAGAAGGCCTGCGGCAAAGAGATGAGCTTATTGAGAAACATGGCTTAGTTATAATCCCCGATGGCACTCCCAATGGTGATGTCAGTCATGAACCAGTGGCTGGAGCCATCACTGTTGTGTCTCAGGAAGCTGCTCAGGTCTTGGAGTCAGCAGGAGAAGGGCCATTAGATGTAAGGCTACGAAAACTTGCTGGAGAGAAGGAAGAACTACTGTCACAGattagaaaactgaagcttcagttagaggAGGAACGACAGAAATGCTCCAGGAATGATGGCACAGTGGGTGACCTGGCAGGACTGCAGAATGGCTCAGACTTGCAGTTCATCGAAATGCAGAGAGATGCCAATAGACAAATTAGCGAATACAAATTTAAGCTTTCAAAAGCAGAACAGGATATAACTACCTTGGAGCAAAGTATTAGCCGGCTTGAGGGACAGGTTCTGAGATATAAAACTGCTGCTGAGAATGCTGAGAAAGTTGAAGATGAATTGAAAGCAGAAAAACGGAAGCTACAACGAGAGTTACGAACAGCACTGGACAAGATTGAGGAGATGGAGATGACCAACAGCCACCTGGCCAAGCGGCTGGAGAAGATGAAGGCCAATAGGACAGCACTTCTGGCCCAGCAGTAGGAAAACCACCCTTCAACCTGGGTGATGCTCCTTGGGGCCCTACCTAGAGGGACTGACTTTTGTCCATTGACACAAACCCCTTTTAGTACTGTTTTGAGTTTTGTCATTAAAACAGCCACCTTTGTATTTTATAATTTATGACAGAATGAAGTCATTTTGAATCTACATGAATGAACACTTTGGATTTTGTTGTAGTTTGATTCTAGGGTAGAACCAGTCCATGCTGTTTTTATTTTTTATCTCCGTAATTGTAGAATCATGTTTACTCAACGTTTTTCCCCAGCTGCCTCAGTAACTGGGCACTCGGAGGCCTTGGCACGGGTTCTGGAGGACAGACAGCAATTCTATGAGTGCTCACTGAGATACTTGCTGGAGACCTCAGAAAACACAAGTGCCTTCTCCACGGTGCAATTCAGACTTCAGTGATCTCCAGTGGTCAAAAGACATTTACCCTTAATATCAGACAACATTTATATTTTAGTGAAGAAACAAGTTCTCGGGTGGGGAATCTATGTTTCACTCAGATTTATATGTTTGGAGGAAAAAAGCCTTTTTTTGTAAAATATTTAAATTTATATAAGAAAATGTTAGAAAAAAATATGGGGAGTGTATATAAAACTTGCTTTATTGCATGGGGCAGGGGAAGTCCAGGCCTAATACTCCTAAAGTAAGAGTTGGGTCCTTTTTTTCTTCAATACAACTGTGCTGTACCTTGTAAAGTATTTTATCTGCTGCTTATTTGTGGAATGAAACCTCAAACAAACCCAAAGggggagggtagggcagggcaggcagATTGGAAATCTGCCTGCAGATTCTATTAAATACACCCTTTTGCCAACCACAATTGGCTACTGACATGTTCATTTTGTTATAGGAGACTTTAAAACAAATCATGGCAACCACATCCCTCTTCTTTTGTCTCCTTCTCAAGGAAAAACAATCTGGAATGTAGAACTTTTAAAGACTTGAGTTTCACCTTTAGAGGTACCCTGTCCAAGAGGTTTTTTTAAAATCATGGAGTGCAACTACTTTGCAGAATTTATGATTCTCTTTTGCTCTTAGTACCCAGGTGGTTTTATAGAAATGATTATTGTATCTTTAAAGTGCTTACACAGAAAATATATTGGGGGAAAATCTAGTGACTAAAGGCACATAAGATAATAAAACTAGACTTTAAAAAGGTAACTCAAAAGTGAATAAAATCTCTAATATTTGTTCCTTT |