| Gene Name | EEF1E1 |
|
| Specie | Homo sapiens | |
| Full Name | eukaryotic translation elongation factor 1 epsilon 1 | |
| Also known as | AIMP3|P18 | |
| Coordinate | chr6:8073360-8102548 | |
| Strand | - | |
| Gene summary | This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| EEF1E1P1 | chr2:111887893-111889478 | + |
Intergenic |
ENSG00000236307 | UCSC |
| >NM_004280.5 |
| GCGTCTGCCAGGAGCTACGGCCGGAAGATGGCGGCGGCCGCAGAGTTGTCGCTACTGGAGAAGTCCCTGGGACTGAGTAAGGGGAATAAATACAGTGCTCAGGGCGAGCGACAGATTCCAGTTCTTCAGACAAACAATGGTCCAAGTCTAACAGGATTGACTACTATAGCAGCTCATCTAGTCAAGCAAGCCAACAAAGAATATTTGCTGGGGAGTACTGCAGAAGAAAAAGCAATCGTTCAGCAGTGGTTAGAATACAGGGTCACTCAAGTAGATGGGCACTCCAGTAAAAATGACATCCACACACTGTTGAAGGATCTTAATTCATATCTTGAAGATAAAGTCTACCTTACAGGGTATAACTTTACATTAGCAGATATACTATTGTACTATGGACTTCATCGCTTTATAGTTGACCTGACAGTTCAAGAAAAGGAGAAATATCTTAATGTGTCTCGCTGGTTTTGTCACATTCAGCATTATCCAGGCATCAGGCAACATCTGTCTAGTGTTGTCTTCATCAAGAACAGACTATATACTAATTCCCACTAGAAGCTGTCCATGCCATACAGAAGATCTATTAAAAATGTTTTAAATGGAAAATGTACTCTAGACCACAGGACTAATGTAAATTAATATACAGTCATTCATTATTTGTTGAAGTTGATAGAATTTTTGAAGTGTAAACTTGTGTCTGAATGTTTTATTTGTTCTTTAGCTGAAGTTTTGCAATTTTTATGTCAAAATTCAATTGCTATTAAACAAGTTGAGATCCAGTTATAAATTAACCTTGTTTTTAGTAGATGACATTTATTTCAATAAAAGTTGCAAATCGGGCTTAATCTTAAAATTGGTGGTCATTTCAATGGTTGACATATTTGGCTATTTATTAACCTCTCTTTCATATTCTAAAATTCATTTTCCCCTTATGGATATTTATGGTAGTTTGTTAAGAACTGATAAATTGTGCCAAGGAAGCCAAAAGGGAAGACAGATGGATTTGTTTTAAAATATTTATGTGAGCTAGTAAATGTGGTTGAAAAAATA |