Summary

Gene Name	TRAF4
Specie	Homo sapiens
Full Name	TNF receptor associated factor 4
Also known as	CART1|MLN62|RNF83
Coordinate	chr17:28744004-28750956
Strand	+
Gene summary	This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

Retrocopy(s) from TRAF4

Retroname	Coord	Strand	Genomic Region	ENSG
TRAF4P1	chr5:143751768-143752749	-	Intergenic	ENSG00000225869	UCSC

Expression

Transcript Sequences

>NM_004295.4

AGTCGGCGCCGCCCGGAGCCGGGAGCGCCGCTCCAGCGAGGCGCGGGCTGTGGGGCCGCCGCGTGCCTGGCcccgctcgcccgtgccggccgctcgcccgccATGCCTGGCTTCGACTACAAGTTCCTGGAGAAGCCCAAGCGACGGCTGCTGTGCCCACTGTGCGGGAAGCCCATGCGCGAGCCTGTGCAGGTTTCCACCTGCGGCCACCGTTTCTGCGATACCTGCCTGCAGGAGTTCCTCAGTGAAGGAGTCTTCAAGTGCCCTGAGGACCAGCTTCCTCTGGACTATGCCAAGATCTACCCAGACCCGGAGCTGGAAGTACAAGTATTGGGCCTGCCTATCCGCTGCATCCACAGTGAGGAGGGCTGCCGCTGGAGTGGGCCACTACGTCATCTACAGGGCCACCTGAATACCTGCAGCTTCAATGTCATTCCCTGCCCTAATCGCTGCCCCATGAAGCTGAGCCGCCGTGATCTACCTGCACACTTGCAGCATGACTGCCCCAAGCGGCGCCTCAAGTGCGAGTTTTGTGGCTGTGACTTCAGTGGGGAGGCCTATGAGAGCCATGAGGGTATGTGCCCCCAGGAGAGTGTCTACTGTGAGAATAAGTGTGGTGCCCGCATGATGCGGCGGCTGCTGGCCCAGCATGCCACCTCTGAGTGCCCCAAGCGCACTCAGCCCTGCACCTACTGCACTAAGGAGTTCGTCTTTGACACCATCCAGAGCCACCAGTACCAGTGCCCAAGGCTGCCTGTTGCCTGCCCCAACCAATGTGGTGTGGGCACTGTGGCTCGGGAGGACCTGCCAGGCCATCTGAAGGACAGCTGTAACACCGCCCTGGTGCTCTGCCCATTCAAAGACTCCGGCTGCAAGCACAGGTGCCCTAAGCTGGCAATGGCACGGCATGTGGAGGAGAGTGTGAAGCCACATCTGGCCATGATGTGTGCCCTGGTGAGCCGGCAACGGCAGGAGCTGCAGGAGCTTCGGCGAGAGCTGGAGGAGCTATCAGTGGGCAGTGATGGCGTGCTCATCTGGAAGATTGGCAGCTATGGACGGCGGCTACAGGAGGCCAAGGCCAAGCCCAACCTTGAGTGCTTCAGCCCAGCCTTCTACACACATAAGTATGGTTACAAGCTGCAGGTGTCTGCATTCCTCAATGGCAATGGCAGTGGTGAGGGCACACACCTCTCACTGTACATTCGTGTGCTGCCTGGTGCCTTTGACAATCTCCTTGAGTGGCCCTTTGCCCGCCGTGTCACCTTCTCCCTGCTGGATCAGAGCGACCCTGGGCTGGCTAAACCACAGCACGTCACTGAGACCTTCCACCCCGACCCAAACTGGAAGAATTTCCAGAAGCCAGGCACGTGGCGGGGCTCCCTGGATGAGAGTTCTCTGGGCTTTGGTTATCCCAAGTTCATCTCCCACCAGGACATTCGAAAGCGAAACTATGTGCGGGATGATGCAGTCTTCATCCGTGCTGCTGTTGAACTGCCCCGGAAGATCCTCAGCTGAGTGCAGGTGGGGTTCGAGGGGAAAGGACGATGGGGCATGACCTCAGTCAGGCACTGGCTGAACTTGGAGAGGGGGCCGGACCCCCGTCAGCTGCTTCTGCTGCCTAGGTTCTGTTACCCCATCCTCCCTCCCCCAGCCACCACCCTCAGGTGCCTCCAATTGGTGCTTCAGCCCTGGCCCCTGTGGGGAACAGGTCTTGGGGTCATGAAGGGCTGGAAACAAGTGACCCCAGGGCCTGTCTCCCTTCTTGGGTAGGGCAGACATGCCTTGGTGCCGGTCACACTCTACACGGACTGAGGTGCCTGCTCAGGTGCTATGTCCCAAGAGCCATAAGGGGGTGGGAATTGGGGAGGGAGAAAGGGTAGTTCAAAGAGTCTGTCTTGAGATCTGATTTTTTCCCCCTTTACCTAGCTGTGCCCCCTCTGGTTATTTATTTCCTTAGTGCCAGGAGGGCACAGCAGGGGAGCCCTGATTTTTAATAAATCCGGAATTGTATTTATTAATTTGCTTCCAGCCTGACTTACCTGGGTTGGTTAGGTCCCTGGGAGGCTCAACCAAACTGAAGGCAAAGAAAGGACCAGTCAGAGAAGGGCCGCTGCCTGGGTCTGGCCCCAGGATCCAGCTTACCTGCTGGCTCGCCCTCTGATGGACGCCGGGAAAACTGCATCGGGCTTTGTGTGGAAGACGGTCCCTGCCACTGCCCTCTGCCGATGAAATGCGGGAAGTGTATGGCCTAGATGTTTCATAAGGCTGGAGTCCCTGGTCAGCCCCACCAGATTAGTGCTTCTACCCTAGGCAGGGCTTTCTTGGTCTAATGGTAATAAGCACCGACACTGCTAAGCACTTTACGTGCATTATTATTTCATTGAAAAGAACTGTCAAGTGAAATACTTTTTAGCACAGTAACTGGCTTTGTGGGCTCTAGAGAAGAGTTAATGAGGCAGTGCATGTTCTTGGCCCAGAGTAAGTGCTTAGTGAATGCTTTCTAACTCCGAACCCCAGCCACATCCAGGGACTGGGTGTTGAGCAAAAGGGGCCTTCAAGATGTTCAAGGCACTTGGATTTTCTCCTGTCTCTCATCGGCTTTTCTTAACGGGCCTCAGTGGGTGCATGTGATTATCCACGTTTCACCTATGAAACATGAACAGAGGAGACTGACTTATCAGTGATTCTTCCGCGGGTTCGGACAGGGCCTCGATTCTGTTTTAAACTCCAGTAGTCCCTAGAAATTGTAGCTCCCTCTAGTTGTGGCAATAGGTGTGGGTCCTTGTGCTTGcttttggcaagtttctgagctacacagggcctccattaccgtcactggtgaaatgcggctcacctcccagatttgttgtaaagattaaatgaactggtcagca