| Gene Name | CFL1 |
|
| Specie | Homo sapiens | |
| Full Name | cofilin 1 | |
| Also known as | CFL|HEL-S-15|cofilin | |
| Coordinate | chr11:65854673-65858180 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| CFL1P1 | chr10:87843831-87844726 | + |
Intergenic |
ENSG00000223820 | UCSC |
| CFL1P6 | chr1:10990847-10991819 | - |
Intergenic |
ENSG00000215785 | UCSC |
| CFL1P9 | chr1:200329247-200329820 | + |
Intergenic |
ENSG00000213045 | UCSC |
| CFL1P4 | chr1:241993205-241994508 | + |
Intergenic |
ENSG00000213026 | UCSC |
| CFL1P8 | chr13:99582780-99583103 | + |
Intergenic |
ENSG00000234239 | UCSC |
| CFL1P2 | chr1:51157438-51158516 | - |
Intergenic |
ENSG00000213478 | UCSC |
| CFL1P10 | chr15:91676754-91677401 | + |
Intergenic |
ENSG00000258540 | UCSC |
| CFL1P3 | chr1:63842682-63843764 | - |
Intragenic Intragenic |
ENSG00000228056 | UCSC |
| CFL1P7 | chr3:25324177-25325777 | + |
Intragenic |
ENSG00000213877 | UCSC |
| CFL1P5 | chr5:69312858-69313945 | - |
Intragenic |
ENSG00000213830 | UCSC |
| >NM_005507.3 |
| GTTCAGTCGGGTCCCGGCAGCGGCTGCAGCGCTCTCGTCTTCTGCGGCTCTCGGTGCCCTCTCCTTTTCGTTTCCGGAAACATGGCCTCCGGTGTGGCTGTCTCTGATGGTGTCATCAAGGTGTTCAACGACATGAAGGTGCGTAAGTCTTCAACGCCAGAGGAGGTGAAGAAGCGCAAGAAGGCGGTGCTCTTCTGCCTGAGTGAGGACAAGAAGAACATCATCCTGGAGGAGGGCAAGGAGATCCTGGTGGGCGATGTGGGCCAGACTGTCGACGACCCCTACGCCACCTTTGTCAAGATGCTGCCAGATAAGGACTGCCGCTATGCCCTCTATGATGCAACCTATGAGACCAAGGAGAGCAAGAAGGAGGATCTGGTGTTTATCTTCTGGGCCCCCGAGTCTGCGCCCCTTAAGAGCAAAATGATTTATGCCAGCTCCAAGGACGCCATCAAGAAGAAGCTGACAGGGATCAAGCATGAATTGCAAGCAAACTGCTACGAGGAGGTCAAGGACCGCTGCACCCTGGCAGAGAAGCTGGGGGGCAGTGCCGTCATCTCCCTGGAGGGCAAGCCTTTGTGAGCCCCTTCTGGCCCCCTGCCTGGAGCATCTGGCAGCCCCACACCTGCCCTTGGGGGTTGCAGGCTGCCCCCTTCCTGCCAGACCGGAGGGGCTGGGGGGATCCCAGCAGGGGGAGGGCAATCCCTTCACCCCAGTTGCCAAACAGACCCCCCACCCCCTGGATTTTCCTTCTCCCTCCATCCCTTGACGGTTCTGGCCTTCCCAAACTGCTTTTGATCTTTTGATTCCTCTTGGGCTGAAGCAGACCAAGTTCCCCCCAGGCACCCCAGTTGTGGGGGAGCCTGTATTTTTTTTAACAACATCCCCATTCCCCACCTGGTCCTCCCCCTTCCCATGCTGCCAACTTCTAACCGCAATAGTGACTCTGTGCTTGTCTGTTTAGTTCTGTGTATAAATGGAATGTTGTGGAGATGACCCCTCCCTGTGCCGGCTGGTTCCTCTCCCTTTTCCCCTGGTCACGGCTACTCATGGAAGCAGGACCAGTAAGGGACCTTCGATTAAAAAAAAAAAAGACAATAATAAAAAGGCTCATTAATGGGATGTGTTTTTCAAGGTTGGGACACAGGAGACTTCAGGATTGGGGGTGCACTGGGATAATGGTGCTATCTCTCTCCTCTGTACTCCACACCCAACCAGCCCCTGCACACCCTTATCTGGCTCCAA |