Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name MSL3
Plot displaying the genomic locations of a parental gene (in chrX) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name MSL complex subunit 3
Also known as MRSXBA|MRXS36|MRXSBA|MSL3L1
Coordinate chrX:11758159-11775772
Strand +
Gene summary This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]

Retrocopy(s) from MSL3

Retroname Coord Strand Genomic Region ENSG
MSL3P1 chr2:233865442-233868323 - Intergenic
 ENSG00000224287 UCSC
MSL3P2 chr7:139171817-139174371 - Intragenic
 ENSG00000239254 UCSC
MSL3P3 chr8:99339629-99341765 - Intragenic
 ENSG00000237704 UCSC

Expression

Transcript Sequences

>NM_001193270.2
GCACGCGCGGTTGGGAGCCTCGCCCATGCTTTGTCGCGTTACCGGGGCTACCGTTTGCGCCCCCGACTGCAACGGTGGCCGCTGAGGGAGGAGGCTTCTCGAATACGGTTTCTGTCTTCGCGTTAAATGTCTCCTTCTGTGCGGCCTGGTGCCGGGTGGGCTCCTGTGGGACGCCCTGGCCGTCCGATCCAGATTGTTGATGTTATTGTTGGGAAAGACGAAAAAGGCAGAAAGATCCCAGAATATCTGATCCATTTTAATGGTTGGAACAGAAGCTGGGATAGATGGGCAGCAGAAGATCATGTGCTTCGTGATACCGATGAAAATCGTAGATTACAGCGTAAATTGGCAAGAAAAGCTGTAGCTCGCCTGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGTTGCCTGGTGTGGACTCTGTCTTAAAAGGCCTCCCCACTGAAGAAAAAGATGAAAATGATGAAAACTCATTAAGCAGTTCCTCTGACTGTAGTGAAAACAAGGATGAAGAAATAAGTGAAGAAAGTGATATTGAAGAAAAGACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAAGAAGGGAAATGGAAGAAAGAACAATAACTATAGAAATCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGATTGTTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATCATAACGATTTTGGAATCCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAATGAGAGGCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCCCAGCAGAAAAGAATGTTGACCTTTGTAAGGAGATGGTGGATGGATTAAGAATAACCTTTGATTACACTCTCCCGTTGGTTTTACTCTATCCATATGAACAAGCTCAGTATAAAAAGGTGACTTCGTCTAAATTTTTTCTTCCAATTAAGGAAAGTGCCACAAGCACTAACAGGAGCCAGGAGGAACTCTCTCCCAGTCCGCCTTTGTTGAATCCATCCACGCCACAGTCCACAGAGAGTCAGCCGACCACCGGTGAACCAGCCACCCCCAAAAGGCGCAAAGCTGAGCCAGAAGCATTGCAGTCTCTGAGGCGGTCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCTGAGAGCAGCGCTTCACCTCAGCCCAAGCGCCGGCAGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCCTGCACCTGGAAAAGAAGACACCTGTGCATAGCAGATCATCTTCACCTATTCCTCTGACTCCTAGCAAGGAAGGGAGTGCTGTGTTTGCTGGCTTTGAAGGGAGAAGAACTAATGAAATAAACGAGGTCCTCTCCTGGAAGCTTGTGCCTGACAATTACCCCCCAGGTGACCAGCCGCCTCCACCCTCTTACATTTATGGGGCACAACATTTGCTGCGATTGTTTGTGAAACTTCCAGAAATCCTTGGAAAGATGTCCTTTTCTGAGAAGAATCTGAAGGCTTTATTGAAGCACTTTGATCTCTTTTTGAGGTTTTTAGCAGAATACCACGATGACTTCTTCCCAGAGTCGGCTTATGTCGCTGCCTGTGAGGCACATTACAGCACCAAGAACCCCCGGGCAATTTATTAAAATGTTGTTGGTTCTGTAAGAGCAACTGCTCTGTCTAGTTTGGCGCTCTGGGTTCCAGGTGAATAACTAACAAGGTGGTGGGTCTTTACCCACAGCGCAAACACAATGCCCACCTTGGGGCTCTGTTGTTTGAGTTGCCCACATACTGCAGTTATTCTGTTAGGAATGATTCCCTGGGTGCCTGAAAGTGCTCTGACACGACACTTGTTACTTTGCAGGCCATCTGTGATGGCAAGGAAAAAGCAACTATGTTCACAGTGAAATATTCGTGGAATAGGTTAGGCCATTTCAGTAGACATTGCAGTTAGTTAGCAAGAACCACATTGTCTCTTTATTTGTTAGCATTAAACAAATTTTTTTTTGCAAATTGGTTTTATTTTTTTGATGAAGCCGAGCAACTCTGTCCAAAAAGGTTTAGTTTGTACTCGGAAACCACAAAGTAGTCTCAAAGTATTTTAGAGGGAATCGATATTGATGGCAAAAGAAAATTTGCAGCTATGCATTTGCTTCTAACGGTTCCCTCTCTGTGAAACATTATTTTTGGTGATCTAAAGAAAGCATTGCCTTTCTTATTTGAGATTTTACAGCTATACTTTGTTGTGTAATGTTATGGTTCCCTTTCTGTAAAATGTTATTTTTGGTGATCTAAATAAAGCCTGTCTTGTTTGAAAGAA