| Gene Name | TMED10 |
|
| Specie | Homo sapiens | |
| Full Name | transmembrane p24 trafficking protein 10 | |
| Also known as | P24(DELTA)|S31I125|S31III125|TMP21|Tmp-21-I|p23|p24d1 | |
| Coordinate | chr14:75131469-75176612 | |
| Strand | - | |
| Gene summary | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| TMED10P2 | chr3:128538027-128539239 | + |
Intergenic |
ENSG00000239405 | UCSC |
| TMED10P1 | chr8:144994871-144998897 | + |
Intergenic |
ENSG00000254618 | UCSC |
| >NM_006827.6 |
| GAGGCCTTCGGTGGTGAACGAGTCTCCAGCACCATGTCTGGTTTGTCTGGCCCACCAGCCCGGCGCGGCCCTTTTCCGTTAGCGTTGCTGCTTTTGTTCCTGCTCGGCCCCAGATTGGTCCTTGCCATCTCCTTCCATCTGCCCATTAACTCTCGCAAGTGCCTCCGTGAGGAGATTCACAAGGACCTGCTAGTGACTGGCGCGTACGAGATCTCCGACCAGTCTGGGGGCGCTGGCGGCCTGCGCAGCCACCTCAAGATCACAGATTCTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAAGTGTGTTTTGAGAGCAAGGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATTGCAAAAGTTGAGAAGCTCAAACCATTAGAGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATGCGTGATACCAACGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTCTCATTGGACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCCTCCCACCTTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGCTTTCTTGCCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTGGTAGGATTTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCAGCATTTGTCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAGTTCTTTTACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCTTTACCCTTAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCATAAAAGTGAGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAacttttttcgtgtatgtgtatttaattctatgcaatattatcacatgtgtagattcatgtgaccaccatcacaagagacagaacagttctgtcacatggatcccttgcactgcccttttacagccgcagccacatccctttcttataccctcaccccaacctgtggctaccactgttctgtcctccatctctgtaattttgtcatttcaagaatgttgtatgaatggaatcatacagaatgtaatcttacgaggctgatcttttttcattcagcataattcccttgaaatccatccaagttgttgcatgtatgaatagtttcttcctttttttcttttaaaaatgttttatatatttagggggtataagtacagatttcttacatgcatatattgcatcgtggtgaagtgggggcagttccttttgattgctgagtagtattccatggtatggatgtaccacagtttgcttaaccattcacccactaaaggacataagagttgttttcagttttttgccctaataaagctgctgtgaacattcatgtacaggtttttatgtgaacatacattttcattttctgggataaatgctcaaaagggcaactgttgggttgtatggtaaacacatatatttttgtaagaaactaccctactctttttccagagtggctctactttttacatacagccactcatacaattcagacagcaatgtatgattgatccagtttcttcacatcctcaccagcatttggtattactactattttttatcttaaccattcacatagatgtgtgtaatgataccacatgtggttttaatttgcatttccaatggctaatgatgttgagtatctttttgtgtgctaatttgccatctatgtatcctcttcggtgaaatgtcttcatgtcttttgtctattttctatttaggtcatttgttctttttactattgagttttgagaggttttttatatatcctagataaaattcctctgttagatatgtggttGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTACTTAATTCCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACTTAAAAATACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTGTGGATATAAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGTTTATCCTTTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAAAGAAACAGAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAAAATCTCAGGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTGGCATAAAAGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGATCCTTAGCATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAATATGTGGGTTAAGATACATCCTTAAACttttttttttttggggggggggggacggagtcttgctgcaacgcccaggctggagtgcaatggcactatctcagctcgctgcaaccttcacctcctgggttcaagcaattctcctgcctcagcctcctgagtagctgggaatataggtgcacaccaccatgcctggctaatttttgtattttcagtagaagcagagtttcaccatattggccaggttggtctcgaactcctgacctcaagtgatctgcctgcctcagcctcccaaagtgctgggattacacgcgtgagccaccacacccagccTCCATCTTTAAACTTTTAAATGTGAAATTTCTATCATGTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTTAGTTATGTTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCCTAAACTTAAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTGGTTTAAAAGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAGCTTTAAAATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTAAGTAAGCCTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGATTCACTTGTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCA |