| Gene Name | Parp1 |
|
| Specie | Mus musculus | |
| Full Name | poly (ADP-ribose) polymerase family, member 1 | |
| Also known as | 5830444G22Rik|ARTD1|Adprp|Adprt1|PARP|PPOL|msPARP|parp-1|sPARP-1 | |
| Coordinate | chr1:180396456-180428564 | |
| Strand | + | |
| Gene summary | Enables NAD+ ADP-ribosyltransferase activity; chromatin binding activity; and protein ADP-ribosylase activity. Involved in negative regulation of telomere maintenance via telomere lengthening; positive regulation of single strand break repair; and voluntary musculoskeletal movement. Acts upstream of or within several processes, including DNA metabolic process; behavioral response to cocaine; and protein poly-ADP-ribosylation. Located in cytoplasm; nucleolus; and nucleoplasm. Part of protein-containing complex. Is expressed in several structures, including Peyer's patch; brain; gut; immune system; and retina. Human ortholog(s) of this gene implicated in several diseases, including arthritis; bacterial meningitis; neurodegenerative disease (multiple); stomach carcinoma; and type 2 diabetes mellitus. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1). [provided by Alliance of Genome Resources, Apr 2022] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| Parp1P1 | chr14:86453051-86453872 | - |
Intergenic |
ENSMUSG00000115014 | UCSC |
| >NM_007415.3 |
| GAGCTTGGGGGGGCGGTCCCGCCGCTAGGCATCAGTAATCTATCCTGAGCGGAGGCGGCTCTGCACGCTTGCGGGGGAAACCGACACGTTAGCGGAGCGCACCAGCGGCGGCGTCGGGCTGCCGCTGCAGCACGAGAAGGAGGATGGCGGAGGCCTCGGAGAGGCTTTATCGAGTGGAGTACGCGAAGAGCGGGCGCGCCTCTTGCAAGAAATGCAGCGAGAGTATTCCCAAGGACTCCCTCCGCATGGCCATCATGGTGCAGTCACCCATGTTCGATGGGAAAGTCCCACACTGGTACCACTTCTCCTGCTTCTGGAAGGTGGGCCACTCCATCCGGCAGCCTGATGTTGAGGTGGATGGCTTCTCTGAGCTGCGCTGGGATGATCAGCAGAAGGTCAAGAAGACGGCCGAGGCTGGAGGCGTGGCAGGCAAAGGCCAGGATGGAAGTGGCGGCAAGGCGGAGAAGACATTGGGTGACTTTTTAGCGGAGTACGCCAAGTCCAACAGGAGCATGTGCAAGGGCTGCCTGGAGAAGATAGAGAAGGGCCAGATGCGCCTGTCCAAGAAGATGGTGGATCCAGAGAAGCCACAGCTGGGTATGATTGACCGCTGGTACCATCCAACTTGCTTTGTCAAGAAGCGGGACGAGCTGGGCTTCCGGCCTGAGTACAGTGCCAGTCAGCTCAAGGGCTTTAGCCTCCTCTCTGCAGAAGACAAAGAAGCTCTGAAGAAGCAGCTCCCGGCCATCAAGAATGAAGGaaagagaaaaggtgacGAGGTGGATGGAACAGATGAAGTGGccaaaaagaaatctaagaaagGGAAGGACAAGGATAGTAGTAAGCTGGAGAAGGCCCTCAAGGCTCAGAATGAGCTGATCTGGAATATCAAAGACGAGCTGAAGAAAGCGTGTTCCACCAACGACCTGAAGGAGCTGCTCATCTTCAACCAGCAGCAGGTGCCGTCAGGAGAGTCAGCGATCTTGGACAGAGTTGCTGACGGCATGGCGTTTGGGGCCCTTCTGCCCTGCAAGGAGTGTTCAGGCCAGCTGGTCTTTAAGAGCGACGCTTATTACTGTACTGGGGATGTCACTGCCTGGACCAAGTGCATGGTCAAGACACAGAATCCTAGCCGAAAGGAATGGGTAACTCCAAAGGAATTCCGAGAAATATCCTACCTCAAGAAGTTAAAGGTCAAAAAACAGGACCGAATATTCCCTCCAGAAAGCAGCGCCCCAGCACCACTGGCACTGCCCCTCTCTGTCACCTCAGCACCCACAGCTGTGAACTCCTCTGCTCCAGCAGACAAGCCCCTGTCTAACATGAAGATCCTGACTCTTGGGAAGCTCTCCCAGAACAAGGACGAAGCAAAAGCTGTGATTGAGAAACTCGGAGGCAAGTTGACAGGATCTGCCAACAAGGCCTCCTTGTGTATCAGCACTAAAAAGGAGGTGGAGAAGATGAGTAAGAAGATGGAGGAAGTGAAAGCGGCCAACGTTCGAGTTGTGTGTGAGGACTTCCTCCAGGACGTGTCTGCCTCCACTAAAAGCCTCCAAGAGCTGCTCTCGGCCCACAGCTTGTCCTCGTGGGGGGCTGAGGTGAAGGCAGAGCCTGGTGAAGTGGTGGCCCCCAAGGGGAAGTCAGCTGCACCCTCCAAGAAGAGCAAGGGTGCTGTCAAGGAGGAAGGTGTCAACAAATCTGAAAAGAGGATGAAATTAACTCTGAAGGGAGGAGCAGCCGTTGATCCTGACTCTGGTCTGGAACACTCTGCACACGTCCTGGAGAAAGGTGGGAAGGTGTTCAGCGCCACACTTGGCCTGGTGGACATTGTGAAAGGGACGAACTCCTATTACAAACTGCAGCTTCTGGAGGACGACAAGGAGAGCAGGTACTGGATCTTCCGGTCCTGGGGCCGGGTGGGCACAGTTATCGGCAGTAACAAACTTGAGCAGATGCCCTCCAAAGAGGACGCTGTTGAGCACTTCATGAAGCTGTATGAAGAGAAGACTGGGAATGCCTGGCACTCGAAAAACTTCACAAAGTATCCCAAGAAGTTCTACCCTCTGGAGATTGACTATGGCCAGGACGAAGAGGCAGTAAAGAAGCTGACGGTGAAGCCTGGCACCAAGTCGAAGCTGCCGAAGCCAGTGCAGGAGCTCGTGGGGATGATCTTCGACGTGGAGAGCATGAAAAAGGCCTTGGTGGAGTACGAGATTGACCTCCAGAAGATGCCCTTGGGGAAGCTGAGCAGAAGGCAGATCCAGGCCGCCTACTCTATCCTCAGCGAGGTCCAGCAGGCAGTGTCTCAAGGCAGCAGTGAATCCCAGATCCTAGATCTCTCCAATCGCTTCTACACTCTGATCCCCCATGACTTTGGAATGAAGAAGCCCCCACTCCTGAACAACGCAGACAGCGTGCAGGCCAAGGTGGAGATGCTAGACAACCTCCTGGACATCGAGGTGGCCTATAGTCTTCTCAGGGGTGGCTCTGACGACAGCAGCAAGGATCCCATCGACGTCAACTACGAGAAACTCAAAACTGACATTAAGGTGGTTGACAGAGATTCTGAAGAGGCCGAGGTCATCAGGAAGTACGTGAAGAACACTCATGCTACCACGCACAACGCCTATGACCTGGAAGTGATCGATATCTTCAAGATAGAGCGCGAGGGGGAGAGCCAGCGCTACAAGCCCTTCAGGCAGCTTCACAACCGGAGGCTGCTGTGGCACGGCTCCAGGACCACCAACTTTGCTGGCATCCTGTCGCAGGGTCTGCGGATAGCCCCACCTGAAGCGCCTGTGACAGGCTACATGTTTGGGAAAGGGATCTACTTTGCCGACATGGTGTCCAAAAGTGCAAACTACTGCCACACATCTCAGGGAGACCCGATTGGCTTAATACTGCTGGGAGAGGTTGCCCTTGGAAACATGTATGAACTCAAGCATGCTTCACATATCAGCAAGTTACCCAAGGGCAAGCACAGTGTCAAAGGTTTGGGAAAAACCACCCCTGACCCTTCGGCCAGCATCACCCTGGAGGGTGTAGAGGTTCCACTGGGAACAGGGATCCCATCTGGTGTCAACGACACCTGCCTGCTGTATAATGAGTACATTGTCTACGACATTGCTCAGGTGAATCTCAAATACCTGCTGAAACTCAAGTTCAATTTTAAGACATCCCTGTGGTAAAGTGCGAGGGGTGGGCTGTGCCCAGCACCCAGGGCCTAGGGGGCAATTCTCCCTAGTGCCTCTGCACCAGACACCACAAAACCTCAGCCATGCTGCCGCCGAAGGGTGGCCCCCTCACCGAATCTCCTTAGGAAGGGTTTTATACAGACAGGTTAAAGGGCTCTGGTTTCAAGTCCCTTGTCCATGCTGCACTGGGGCAGGCCGGTTGTTTGTGGTTTGTCCTACCAGCCACAGCTCCATAGACAGCAGCTGGCAGTAGAGCAAAAGTTGGGGAGAGGATTTTGTTGTTTGCCTAGACTAGTCCTGAGGGAAGAAACACCACGTCACAGTCACGATGTCTGCCTTACTGGCTTCCCCAGGGAAGGAAAAATGTGCTTCCTCCCTTTTTTCAAGGGTTCATCTTTGCTTTAATTTTGGCAAAATGTTAAGCATTTATTTTGagctaaaaataaaagttaatttcATACt |