Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Gene Name NTAN1
Plot displaying the genomic locations of a parental gene (in chr16) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name N-terminal asparagine amidase
Also known as PNAA|PNAD
Coordinate chr16:15037853-15056074
Strand -
Gene summary The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Retrocopy(s) from NTAN1

Retroname Coord Strand Genomic Region ENSG
NTAN1P2 chr8:86481607-86483023 - Intragenic
ENSG00000250569 UCSC

Expression

Transcript Sequences

>NM_173474.4
GAggcgggacgcgcggcccgaggggcgggggcggcgggcggcCCGGGGCTGCAAAGCGGGGGGCCGCCGCCTCCCTGGGCCTGCCTGGGCGGCCGCCTCCGCGATGCCGCTGCTCGTCGAGGGGCGGCGAGTGCGGCTGCCGCAGTCAGCCGGGGACCTCGTCCGAGCCCACCCGCCTTTGGAGGAAAGAGCCAGACTTCTCAGAGGTCAGTCTGTTCAACAAGTGGGACCCCAGGGCCTTCTGTATGTTCAGCAAAGAGAGCTTGCAGTGACCTCCCCAAAGGATGGCTCCATCTCCATTCTGGGTTCTGATGATGCCACTACTTGTCACATTGTGGTCCTGAGGCACACAGGTAATGGGGCCACCTGCTTGACACATTGTGACGGAACCGACACCAAAGCTGAGGTCCCCTTGATCATGAACTCCATAAAATCCTTTTCTGACCACGCTCAATGTGGAAGGCTGGAAGTACACCTTGTTGGAGGCTTCAGTGACGACAGGCAGTTGTCACAAAAACTCACTCATCAACTTCTTAGTGAATTTGACAGGCAAGAAGATGACATTCACTTAGTGACATTATGTGTGACAGAATTAAATGACCGGGAAGAAAACGAAAACCACTTTCCAGTAATATATGGCATTGCTGTCAACATTAAGACTGCAGAGATTTACAGAGCATCCTTTCAAGATCGGGGTCCGGAGGAGCAGCTTCGTGCTGCGCGAACTTTAGCAGGAGGACCAATGATTAGCATTTATGATGCAGAGACAGAACAACTTCGTATAGGACCGTACTCCTGGACACCATTTCCACATGTGGATTTCTGGTTGCACCAAGATGACAAGCAAATACTAGAGAATCTTTCCACTTCGCCTCTGGCTGAGCCACCCCACTTTGTTGAACATATTAGATCTACCTTGATGTTTTTAAAAAAACACCCATCTCCAGCTCACACACTGTTTTCTGGAAATAAAGCCCTACTCTACAAAAAAAATGAAGATGGCTTGTGGGAAAAGATCTCTTCTCCAGGAAGTTAAAAAACATGAATTACCAAAGAAAGCACCTTCTTGGCCTGACAGACCATTGGTGGGGCTGGCACGAATCCAGATCTGGATCCTACATCTGTTGGGTCTTAGGCCTCCTTCCCTCCTCAGTGTCTTTCAAATGACTTTCATCAAATGACTTTCAAAATAAAACCTTATTTTGGCAAA