Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Fkbp1a
Plot displaying the genomic locations of a parental gene (in chr2) and its retrocopy(ies). Each line represents a retrocopy.
Specie Mus musculus
Full Name FK506 binding protein 1a
Also known as FKBP12|Fkbp|Fkbp1
Coordinate chr2:151384403-151403611
Strand +
Gene summary This gene is a member of the immunophilin family. The encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, and is associated with immunoregulation, protein folding, receptor signaling, protein trafficking and T-cell activation. It may modulate the calcium release activity of the ryanodine receptor Ryr1. It also interacts with the type I TGF-beta receptor. Disruption of this gene in mouse causes severe ventricular defects. Pseudogenes of this gene have been defined on chromosomes 4, 10, 14, and 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Retrocopy(s) from Fkbp1a

Retroname Coord Strand Genomic Region ENSG
Fkbp1aP1 chr10:21285051-21286410 - Intergenic
 ENSMUSG00000112405 UCSC
Fkbp1aP2 chr14:76872870-76874346 - Intergenic
 ENSMUSG00000115143 UCSC
Fkbp1aP3 chr16:80746591-80747073 + Intergenic
 ENSMUSG00000116566 UCSC

Expression

Transcript Sequences

>NM_008019.3
TTCCGGTCCCTCCGCCTAGCTGCCCCGCTTCAGGGATGTGAGCGCCTCGCGCAAATAGGGCGGGGCGTGCCGTGCGGTGCGGTGCGCGTGCGCAGGAGCCACGAGAGGGACGAAGCCGAACCTCTGAACCGCCGCCAGGTCCGCTCCGGCTCCACGCCGCCCGTCGCGCCGCCACCCGcgtccttttcctcctcctccgccaacgccgccgccgccgccgccgccatggGAGTGCAGGTGGAGACCATCTCTCCTGGAGACGGGCGCACCTTCCCAAAGCGCGGCCAGACCTGCGTGGTGCACTACACGGGGATGCTTGAAGATGGAAAGAAATTTGATTCCTCTCGGGACAGAAACAAGCCTTTTAAGTTTACACTAGGCAAGCAGGAGGTGATCCGAGGCTGGGAGGAAGGGGTAGCCCAGATGAGTGTGGGTCAGAGAGCCAAACTGATAATCTCCTCAGACTATGCCTATGGAGCCACCGGGCACCCAGGCATCATCCCACCACATGCCACTCTTGTTTTTGATGTGGAGCTTCTAAAACTGGAATGACAGAAGTGGCCTCCTCCCTTAGCTCTGCACGTGGATCTGCCATGGAGGAATCTGGTACCTCCAGATGGGTGCACATGAATCCATGGGGAGCTCTTCCTGACGTCCCACCACCCTTTGTATAGACACCTACCCGACTGAATGTGTTCCGTCACTCAGCTTTGCTTCGGACACCTCCATGTCCTCTTCccccctctgtatgtgtgttgacCTAAACTATATGCCATAAACCTCAAGTTACTTTATTTTGGGGTGAAGACTCAGTTTCTGTTTCAGATCTAAGTTTCCAATGAAGTATATTGTCAAGTGTTAACAGCACAAGCGATGGGTTAACTTAGAATAGAAATTGGTGTTGGGGGGGGATTtgcaagaatttttattttattttattttaattttttggatGAAAATTTTATCTATTATATATTAAGACATTCTGCTGCTGTGCTGCAAAGCCATAGCAGATTCGAGATGCTGTTGAGGGCTGGATTTTTCTCTAGTGAGGGAGGTCCTGTTAAACTGAAAGCCCTACCCAAACTGAGGTGGGAAGGAAGCGGGGGAGAGAGCCTTGGCTTCTGACAGTCCTTCCACCTTCTGAAACTAGCTGCCTTTTAAAGCAGATCCCTTCACTGCTATGTTGGACACTACAGTATCTGTCCCTGGGTTGGCAGAGACTTGAAAGCCTTTGTGACCTGGCTTAATTTGTTTTTCATCCTATGGTTTTTCTAATGGATTTTCTGGACTTTTGTAATCTTGTAACTATTCAAGCTCCACTTTCTAAATTTTAAGAACTTCAGTGGAAAGTTTAAATTGAAGGTGCTGTTTGTAGACTCACCACCCAACGGACGCCCAGCCACCACGGCAAATCCTTGAGTGTTCTCTAAGAATACGATGCTGGTCATCACAGCTTCAGCATCTCCTGGGTTTTGATGCTTGGCTCTTTGCTGATCTTGGCTTCCTGGCTTttcctccttcagttccttctcaccCTCTGCTGTCCTTGTGTAGTGATTTGGTGAGAGAAAGCTTTTGTCCCCTGCCCTCTGCACTACATATGCGGTTCAAGTTTTATTATTGCAATAAAAGTGCTTTATGCTGGCTTTTCTCA