Summary

Gene Name	CRYZ
Specie	Homo sapiens
Full Name	crystallin zeta
Also known as	-
Coordinate	chr1:74705470-74733115
Strand	-
Gene summary	Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

Retrocopy(s) from CRYZ

Retroname	Coord	Strand	Genomic Region	ENSG
CRYZP1	chr7:103087844-103089673	-	Intragenic	ENSG00000233025	UCSC

Expression

Transcript Sequences

>NM_001889.4

GTGGAGCCTGCAAAAGTTGGAGAAGGTGTGGCAGTCCTCATTTCTGTGGAATCTGAAGAAGCCCACGCAGATTTTAATTCCCACTCTAGATTCTGTATCTAGATCACCATGGCGACTGGACAGAAGTTGATGAGAGCTGTTAGAGTTTTTGAATTTGGTGGGCCAGAAGTCCTGAAATTGCGATCAGATATTGCAGTACCGATTCCAAAAGACCATCAGGTTCTAATCAAGGTCCATGCATGTGGTGTCAACCCCGTGGAGACATACATTCGCTCTGGTACTTATAGTAGAAAACCACTCTTACCCTATACTCCTGGCTCAGATGTGGCTGGGGTGATAGAAGCTGTTGGAGATAATGCATCTGCTTTCAAGAAAGGTGACAGAGTTTTCACTAGCAGCACGATCTCTGGGGGTTATGCAGAGTATGCTCTTGCAGCAGACCACACTGTTTACAAACTACCTGAAAAACTGGACTTTAAACAAGGAGCTGCCATCGGCATTCCATATTTTACTGCTTATCGAGCTCTGATCCACAGTGCCTGTGTGAAAGCTGGAGAGAGTGTTCTGGTTCATGGGGCAAGTGGAGGAGTTGGATTAGCAGCATGCCAAATTGCTAGAGCTTATGGCTTAAAGATTTTGGGCACTGCTGGTACTGAGGAAGGACAAAAGATTGTTTTGCAAAATGGAGCCCATGAAGTGTTCAATCACAGAGAAGTGAATTACATTGATAAAATTAAGAAGTATGTTGGTGAGAAAGGAATTGATATAATTATTGAAATGTTAGCTAATGTAAATCTTAGTAAAGACTTGAGTCTTCTGTCACATGGAGGACGAGTGATAGTTGTTGGCAGCAGAGGTACTATTGAAATAAACCCACGAGACACCATGGCAAAGGAGTCGAGTATAATTGGAGTTACTCTCTTTTCCTCAACCAAGGAGGAATTTCAGCAATATGCAGCAGCCCTTCAAGCTGGAATGGAAATTGGCTGGTTGAAACCTGTGATAGGTTCTCAATATCCATTGGAGAAGGTGGCCGAGGCTCATGAAAATATCATTCATGGTAGTGGGGCTACTGGAAAAATGATTCTTCTCTTATGATGATTAATTCTTTCATGGATTTCCTATGTAATTAGAGGTACTGTCTTTCCCCCAGTTGTACTTACCCTATCTTTTCTTTAATTAACATTCGATTCCATGAGCTTCTTATGTGAAAAAATAAGATTTTTCTTTAGAGAGCAGAAGCAGAAGAGTAAAATTTATTGTATAGCTAGCAATATTTTTTTATGCCATCTGTCTCAAATCAAAGAGTCATCATAGTAGGAAATAACATGTTAGTTGTCATTTGGCATGAGTGTGCATTCCAGTAATTCTTAATTGATATTTGATTAATTCCATACCTTTGATTAAAACATGCTAGTTCAAAATAAGACTGCTCAGTTTCCAAGGGTTTTCAAGCCTACTTACCTTTATAAAGGTTCTCTAGTCTCTGATTAGCCATGACTGTATTGGACTTTGAACATTTTCTGAACTAAAAACCTCTATTCTAAACTAATCTCATTTGGATGTGTAAGTCTTTTGTAAAGGCAAGAATAAATAATATCCAGGACAATTTATTAGTTTTCTCAGTATTTTCCCAAATATTAGAATATTTACTTCATTATTGGTTGGCTGCCAATGACCCCATATGTTCTGTGAGAATAGTAGCTTTATCTTTGATATAATACATAGTCTCCAAATAGGTAATACTTCGCAATTGATTAGATTTTCAGAGTAGATTTAGAGTTATCTGTTTTTCTGGTGAGGGTCAAATATTTTTGTTAATTAAGCTCACAAATTTGATAAATTAAGAATTATCTGCATTTGTCTCGTAACATAATAATGTGTAATAAAGTCTATAGAAAATTAAAA