| Gene Name | DAD1 |
|
| Specie | Homo sapiens | |
| Full Name | defender against cell death 1 | |
| Also known as | OST2 | |
| Coordinate | chr14:22564907-22589224 | |
| Strand | - | |
| Gene summary | DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| DAD1P1 | chr12:24917851-24918285 | - |
Intragenic |
N/A | UCSC |
| >NM_001344.4 |
| ACATCCGGTGTGGTCGACGGGTCCTCCAAGAGTTTGGGGCGCGGACCGGAGTACCTTGCGTGCAGTTATGTCGGCGTCGGTAGTGTCTGTCATTTCGCGGTTCTTAGAAGAGTACTTGAGCTCCACTCCGCAGCGTCTGAAGTTGCTGGACGCGTACCTGCTGTATATACTGCTGACCGGGGCGCTGCAGTTCGGTTACTGTCTCCTCGTGGGGACCTTCCCCTTCAACTCTTTTCTCTCGGGCTTCATCTCTTGTGTGGGGAGTTTCATCCTAGCGGTTTGCCTGAGAATACAGATCAACCCACAGAACAAAGCGGATTTCCAAGGCATCTCCCCAGAGCGAGCCTTTGCTGATTTTCTCTTTGCCAGCACCATCCTGCACCTTGTTGTCATGAACTTTGTTGGCTGAATCATTCTCATTTACTTAATTGAGGAGTAGGAGACTAAAAGAATGTTCACTCTTTGAATTTCCTGGATAAGAGTTCTGGAGATGGCAGCTTATTGGACACATGGATTTTCTTCAGATTTGCACTTACTGCTAGCTCTGCTTTTTATGCAGGAGAAAAGCCCAGAGTTCACTGTGTGTCAGAACAACTTTCTAACAAACATTTATTAATCCAGCCTCTGCCTTTCATTAAATGTAACCTTTTGCCTTCCAAATTAAAGAACTCCATGCCACTCCTC |