Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name DUSP5
Plot displaying the genomic locations of a parental gene (in chr10) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name dual specificity phosphatase 5
Also known as DUSP|HVH3
Coordinate chr10:110497907-110511533
Strand +
Gene summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008]

Retrocopy(s) from DUSP5

Retroname Coord Strand Genomic Region ENSG
DUSP5P1 chr1:228650486-228652296 + Intergenic
 ENSG00000183929 UCSC
DUSP5P2 chr3:9601712-9601864 + Intergenic
 ENSG00000235338 UCSC

Expression

Transcript Sequences

>NM_004419.4
GGCTTCTAgggcggcgagcggccgggctggctatcgagcgagcggggcgggAACGCGGAGTTGCGCCGCCGCTCGGGCGCCGGGCTCCGTCGCGGCCGCAGCCCCGCGGGTCGCCCTCCCGTGCCTCGCCCGCGGACACCCTGGCCGTGGACACCCTGGCCGTGGGCACCcgcggggcgcgcggcgcggggccgctggccggcggcggcggcggcATGAAGGTCACGTCGCTCGACGGGCGCCAGCTGCGCAAGATGCTCCGCAAGGAGGCGGCGGCGCGCTGCGTGGTGCTCGACTGCCGGCCCTATCTGGCCTTCGCTGCCTCGAACGTGCGCGGCTCGCTCAACGTCAACCTCAACTCGGTGGTGCTGCGGCGGGCCCGGGGCGGCGCGGTGTCGGCGCGCTACGTGCTGCCCGACGAGGCGGCGCGCGCGCGGCTCCTGCAGGAGGGCGGCGGCGGCGTCGCGGCCGTGGTGGTGCTGGACCAGGGCAGCCGCCACTGGCAGAAGCTGCGAGAGGAGAGCGCCGCGCGTGTCGTCCTCACCTCGCTACTCGCTTGCCTACCCGCCGGCCCGCGGGTCTACTTCCTCAAAGGGGGATATGAGACTTTCTACTCGGAATATCCTGAGTGTTGCGTGGATGTAAAACCCATTTCACAAGAGAAGATTGAGAGTGAGAGAGCCCTCATCAGCCAGTGTGGAAAACCAGTGGTAAATGTCAGCTACAGGCCAGCTTATGACCAGGGTGGCCCAGTTGAAATCCTTCCCTTCCTCTACCTTGGAAGTGCCTACCATGCATCCAAGTGCGAGTTCCTCGCCAACCTGCACATCACAGCCCTGCTGAATGTCTCCCGACGGACCTCCGAGGCCTGCGCGACCCACCTACACTACAAATGGATCCCTGTGGAAGACAGCCACACGGCTGACATTAGCTCCCACTTTCAAGAAGCAATAGACTTCATTGACTGTGTCAGGGAAAAGGGAGGCAAGGTCCTGGTCCACTGTGAGGCTGGGATCTCCCGTTCACCCACCATCTGCATGGCTTACCTTATGAAGACCAAGCAGTTCCGCCTGAAGGAGGCCTTCGATTACATCAAGCAGAGGAGGAGCATGGTCTCGCCCAACTTTGGCTTCATGGGCCAGCTCCTGCAGTACGAATCTGAGATCCTGCCCTCCACGCCCAACCCCCAGCCTCCCTCCTGCCAAGGGGAGGCAGCAGGCTCTTCACTGATAGGCCATTTGCAGACACTGAGCCCTGACATGCAGGGTGCCTACTGCACATTCCCTGCCTCGGTGCTGGCACCGGTGCCTACCCACTCAACAGTCTCAGAGCTCAGCAGAAGCCCTGTGGCAACGGCCACATCCTGCTAAAACTGGGATGGAGGAATCGGCCCAGCCCCAAGAGCAACTGTGATTTTTGTTTTTAAGACTCATGGACATTTCATACCTGTGCAATACTGAAGACCTCATTCTGTCATGCTGCCCCAGTGAGATAGTGAGTGGTCACCAGGCTTGCAAATGAACTTCAGACGGACCTCAGGGTAGGTTCTCGGGACTGAAGGAAGGCCAAGCCATTACGGGAGCACAGCATGTGCTGACTACTGTACTTCCAGACCCCTGCCCTCTTGGGACTGCCCAGTCCTTGCACCTCAGAGTTCGCCTTTTCATTTCAAGCATAAGGCAATAAATACCTGCAGCAACGTGGGAGAAAGAAGTTGCTGGACCAGGAGAAAAGGCAGTTATGAAGCCAATTCATTTTGAAGGAAGCACAATTTCCACCTTATTTTTTGAACTTTGGCAGTTTCAATGTCTGTCTCTGTtgcttcggggcataagctgatcaccgtctagttgggaaAGTAACCCTACAGGGTTTGTAGGGACATGATCAGCATCCTGATTTGAACCCTGAAATGTTGTGTAGACACCCTCTTGGGTCCAATGAGGTAGTTGGTTGAAGTAGCAAGATGTTGGCTTTTCTGGATTTTTTTTGCCATGGGTTCTTCACTGACCTTGGACTTTGGCATGATTCTTAGTCATACTTGAACTTGTCTCATTCCACCTCTTCTCAGAGCAACTCTTCCTTTGGGAAAAGAGTTCTTCAGATCATAGACCAAAAAAGTCATACCTTCGAGGTGGTAGCAGTAGATTCCAGGAGGAGAAGGGTACTTGCTAGGTATCCTGGGTCAGTGGCGGTGCAAACTGGTTTCCTCAGCTGCCTGTCCTTCTGTGTGCTTATGTCTCTTGTGACAATTGTTTTCCTCCCTGCCCCTGGAGGTTGTCTTCAAGCTGTGGACTTCTGGGATTTGCAGATTTTGCAACGTGGTACTACTTTTTTTTTCTTTTTGTCTGTTAGTTATTTCTCCAGGGGAAAAGGCAATAATTTTCTAAGACCCGTGTGAATGTGAAGAAAAGCAGTATGTTACTGgttgttgttgttgttcttgtttttTATAGTGTAAAATAAAAATAGTAAAA