Summary

Gene Name	Rbpj
Specie	Mus musculus
Full Name	recombination signal binding protein for immunoglobulin kappa J region
Also known as	CBF1|Igkjrb|Igkrsbp|RBP-J|RBP-J kappa|RBP-Jkappa|RBPjk|Rbpsuh
Coordinate	chr5:53713121-53814787
Strand	+
Gene summary	Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein N-terminus binding activity. Involved in several processes, including circulatory system development; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; blood vessel morphogenesis; and regulation of transcription, DNA-templated. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; neural ectoderm; paraxial mesenchyme; and retina. Used to study aortic valve disease. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and dilated cardiomyopathy. Orthologous to human RBPJ (recombination signal binding protein for immunoglobulin kappa J region). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Rbpj

Retroname	Coord	Strand	Genomic Region	ENSG
RbpjP2	chr6:46503867-46507818	-	Intragenic	ENSMUSG00000079575	UCSC
RbpjP1	chr4:49350662-49351526	+	Intergenic	ENSMUSG00000081770	UCSC

Expression

Transcript Sequences

>NM_001080928.1

CCTTCAAGATATCCAGCAAGTTGAGACTGGGTCCCACTCTGTAGCTCCGGCTGCTGTGGAATTTACAGCATAGCCCAGAACTCGAGGCGTCTGCTTAACCCGGCTTCTCAAATGTTGGCCTATAGGAAGTTTGGTGAGCGGCCTCCACCCAAACGACTCACTAGGGAAGCTATGCGAAATTATTTAAAAGAACGAGGGGATCAAACAGTGCTCATTCTTCATGCAAAAGTTGCACAGAAGTCTTACGGAAATGAAAAACGattTTTTTGCCCTCCTCCTTGTGTGTATCTTATGGGCAGtggttggaagaaaaaaaaagagcaaatggAACGAGATGGATGTTCTGAACAAGAGTCTCAACCCTGTGCGTTTATTGGAATAGGAAACAGTGACCAAGAAATGCAGCAGCTGAACTTGGAAGGGAAGAACTACTGTACAGCCAAAACATTGTACATATCTGATTCAGACAAGAGAAAACATTTCATGTTGTCTGTAAAGATGTTCTATGGCAACAGCGATGACATTGGTGTGTTCCTCAGCAAGCGGATAAAGGTCATCTCCAAACCCTCCAAAAAGAAGCAGTCACTGAAGAATGCTGACTTGTGCATTGCTTCAGGAACGAAGGTGGCACTGTTCAATCGCCTTCGGTCCCAGACAGTTAGTACCAGGTACCTGCATGTAGAAGGAGGGAATTTCCACGCCAGTTCACAACAGTGGGGAGCATTTTACATCCATCTCTTGGACGACGACGAGTCGGAAGGAGAGGAGTTCACAGTTAGAGATGGCTACATCCATTACGGGCAGACTGTCAAGCTTGTGTGCTCAGTGACTGGCATGGCACTCCCAAGATTGATAATTAGGAAAGTTGATAAGCAGACGGCATTACTGGATGCAGACGACCCTGTATCACAACTCCACAAATGTGCATTTTACCTTAAGGATACAGAAAGAATGTACTTGTGCCTTTCTCAAGAAAGAATAATCCAATTTCAGGCCACTCCATGtccaaaagaacaaaataaggAAATGATAAACGATGGAGCTTCCTGGACAATCATTAGCACAGACAAGGCCGAGTACACGTTCTATGAGGGAATGGGCCCCGTCCTTGCCCCAGTCACCCCTGTGCCTGTCGTAGAAAGTCTTCAGTTGAATGGCGGCGGGGACGTAGCAATGCTTGAACTTACAGGACAAAACTTTACTCCAAATTTAAGAGTGTGGTTTGGGGATGTAGAAGCCGAAACAATGTACAGatgtggagagaGCATGCTCTGTGTGGTCCCAGACATTTCTGCATTCCGGGAAGGTTGGAGATGGGTCCGCCAGCCAGTCCAGGTTCCAGTGACTTTGGTCCGAAATGACGGGGTCATTTACTCCACCAGCCTTACCTTCACCTACACACCAGAGCCAGGGCCGAGGCCACACTGCAGCGCTGCAGGAGCGATTCTCAGAGCCAACTCCAGCCAAGTGCCCTCCAATGAGTCAAACACAAACAGCGAGGGGAattacacaaatgccagcacaaaTTCTACCAGTGTCACATCGTCCACAGCAACCGTGGTGTCCTAACTACCGTCTTTTTGCTGGGACTGAAACTGACTTGAATGCAGCAAAAAGTTGACAGAGAAAGGCAAGGATAAAGTGAACAATCTTTTGTGGTTTCTTGGGGAAACGTTTCGTACCAGGTGATCTATTCAAAACTGCCAGTGCAGGTGTGACATGCAGAGGCCACAGTACAATGAACAACATCAGAATGCACAGGCTGATGGAAATCCAGGTTTTCAGCTGTCCCTCTCACACGCACccctttttggttgttttggtttggttttgatttaatGGCCAGGAAACAGatatgtggctggagcacaggctAAGCTAGAAGACACAAACCTAACATAGACTTATGGACCAAGGGACTCGCATAAGCTTTAGTGAAAGGTACATTTTCACCATGCCTTTTTTATATCACAGTGTGTACTACACCTTGTTACCAAACAGGTTGCGCTCCCCACCCTTTGAGGGTTGGCTCTAAAGTACATTCATTCAGGTTCGAGCCTCACCATGTTTGTTCAGTCTGAACACTGAACACTTCCAGGTTCTTGTGGTCTAAGGCTGGAACTTTTTTAAGCTGAAGTCTTATGACTTTTTCATAAGTTGGAATTATTTTGATTTCAGCAAGTCAAATTTTGTAAAGGCCtgcatattttttttaagattatatgaAGTCTGCAAAAGCTTTAAAAATGCCTCTGCCTTGCCTGCAATACATGCAATGTGTGTTAACTGAGTCTGTTCTCAGAATCTGTTGGTAGTTATTTCtgtgttttccctttttttaaagaaatgtatttatagTGGTAATCTAAGAGATGCTAACAGCTCCGTGTGGCCATTTAGCCCTTTCTGAGTTCATGGCAGTGAGCACTGCCGTTCGAAGGCTGTGCGCCTCTGCCTGTTCATCAGTTCATCTGTGTTCCAGGATTTGTTCAGGTTTCCCCTTCCCCCAAATCTTGTACATAACTTGTATTAtgtgtaagttaaacattttaTCTTTACTTGGAATGTTCCCAGTGATTACATTTCACAGGGTGTTTCCCACCTTGTTGGCAAATGACAAAAAATATCATGCGAATTATTTGCTACCAAGATGGTGCCCGTAGGGTAAAATGAGGAACATCTCTGCAGGATGATTTAttgtatgttttcctttttttttagccTAGCCAGAACATCATTATAATTTTAAAGACCATAAGATGGCTTTTATTAGATGATAACTAAATAAACTGAACTAAGTAGCCAGAAGACAGTACCTTAGAGACTGATAGTTGTAagtttataaaaatacaaatgtaacttatatttccattttcctcTTTGCCCCTTTGTTTATTTTCCCCAGTAGAAATGTTCtgtccagatttttttccccctttttagtTAAGCCTTGCTTGCATTCAGGCTTGTGTGTCAGCCCTGTGTGCCAATATGCCAGATTCATTTTGTTTCCATCCCTGCACTTTGGTTATTCCTTGTTCAGTTTCTTGGGAATTGAAGCAGACTCATTGGGCTACATTTAGTACAAGAACCACATGTGTGATGTTAAAGGACACAGTCTAGTGATGCCATCATCCTTGAGTAAAAACTACCTCTAGATTGTGGTAAGCTTTTACTGTCCCTTAAAACAGGAGCCACTAGTACCTTATGAATGCAGACTGTAACTTCTATGGCATTTTCTGGTGTCTTtctggctctctgggcttctgAAAGTTTTCACGTAGACCCTTAGACTCCTCTGTCAGGACCATTGCTTTCCAGCGTTGCTGCTTTCACTCGCTGTCTCGAAGACTGTACCACTGTAAGTGCCACTGCGAACATCTTTAAACGGCTCCTCCTTGGCTTGTCAAGGGGAAGGCCACCTGTAAGATGTGGTGGTGACAGCCTTCCTGTCCACCCCAGGCTGCTCCTTACCAGCTGTTCTAGCCGATTCTCTTCAGATCAGCTACAGCCCACCTCCTCCCCGCCCCGCCTCACCCCTCCAGGCTGTCTCAGTGGTCCAGGGCAGAGCTCACTGTGGCCTTACTGATCTATCTCTGCAGTAACTGTTCTCCCTCAGTTGCGATGGAAGCAGGCCCCTGCGATCTGTTCAGAGCCTGAGCAGTTTGCAGTTCCGTTGTGCTTTCTGAGGTCCTAGATTCAGGATGTAGTTAAGTCGATAACTGAGAACAGATGAGATGCTTTTAAAGAACAAACTCTTCCTTACCCAGCTTTGTAGCTTAAAGTAAGTTTTCAAGTTCATGGCTTTATTAAAATGaactttgactttttaaaatgcttataTCTCATTTcggttcttttgtttattttagtaaGAATTGAAACAGACTATAAGtagttttcctgtttgtttgtttgtttgtttgttttttacaaagtTCAAGAATGTAACAATAAAGGCATTTTGCTATGGTTCTATGTCAGACTCCTACCACAGAATAGTGTGAACAGATATGTCTGTCTGCTTTACCATGTTATTGATAGTTCTTTTGTCAGCTGCTTTTATTAAAAGTCCTCTTTTGTGAATTTGTAAATCAATTTCAATATATGATGTACAGGAGTCTTGTCCCCCGTTACTGTGGAATGTTCCCCCCTGTTGATGCTGGTCCCTTTATCCTCTTATCTTCTTAGAACCGGGAATTCTTCAGTTGTGGTGTGTGGCTGTATTTTTCTATTCTGTTTACAGTGCGTCTACACAGCTTCTTAAAACATGTCGAAATGCAGAATCCAAGATCCACCATGAATTTGTCAAGAGATTGGAAGGCAGGCCAAAACCTGAAAATGTGGGGTGCCCTTTGTACAATTGCAGAGTCAAGCACTAGTGGGAGTTTGAACTGGCTACTGACCGCTCTTAAACTGTGGCAGTGTCCTTGGGTACAGTTAACTAGCAGAACCTGCTGTCACTCTTCCTGCCACCATCTTAACCTTgacagttttgtttcttttctgtgtggTGCTGGGGTCAAATCCAGAGCCTTAGGCTTGCtaaggctttttgtttgtttgatttttccttGAGACAAGTGTCTCACCCATGGAGCCCCTCAGCATTCTTGAAAGTCTCTGCCTTAGCCTCCAGGTCCTGTGGTACCAGGTGTGGCAGGATGCTTTTGTCATTAGAGAAACTGGTCTGTGTCCAACCACAGAAAAATTCCAATGCAGTTTTTAATAATTAATCCACTAGTTATTTAATCAAAATCTTTTTGTAGGGAGAGattcctgtttgaaagaaaatgCTATTTGATTATTAACCAAGGTAACAGACACTGCTTTCCAAAGCAGCTGTGTTTCTGGTGAGTACTGAAcaaatgtgtggttttctgtgCCACCTTTGATTCATTTTTCAAGCACTGTTACTCGGGATGGATGGTTAGAAACATGATATTTTAGTGTTTCTACTTAACCCTTTCAGGACCGAGCTGTATTGCCTTTCTATTAATTTCCCCCTGTGTTGTGATAAATGTTTGCTCGTGTTCAGTCCTGTGTCAGTCCAGACGTAGGTTTGTGTAAAAGCTCAGTTGTAGCTTATTTCTTGTACCTTGCAGCATGTTCTACGCATCCAGTCCTTAAGGGGTTTACTCTACAAACTGTGCACCTGCGTGTAAGGGTCATTAGCAATAAGATAGAAAATTGAGCAAGTTTATACCATAATTTTGTAGAAAAAGGAATCTGCTCAATTCCATATTTCATCCATGAAAACTCTGCAATACGGGCAGTTTCtaggaataaataaaaaggagatgCAAACCATTGTAGATGTCTTCTGTGGGATGTGCCCGATGCGTGCATCATCGTCTTTGATTCCAGGTACTtcataaagataaaattaaattc

>NM_001359152.1

GGTAGGTTTCTAGGGAAAGGCAGTGAGCAGATCCCTTAGTCCGCGGGCGGCGCGAGGCGGCTGGCtcccggcggcggcggcggcgaagCGGGGAAAGACGGCGCGGGGGCCGGGTGGCAGCGATCGGCGAGGCCGAGGGAAGGGGCGGGGGAGAGGAGCAGGGAAAGGCGGCGGGGGGAATCTCGCGAGGGTTGGAGTTTTGGCGAGAGTTTGTGGAAGATGGCGCCTGTTGTGACAGGGAAGTTTGGTGAGCGGCCTCCACCCAAACGACTCACTAGGGAAGCTATGCGAAATTATTTAAAAGAACGAGGGGATCAAACAGTGCTCATTCTTCATGCAAAAGTTGCACAGAAGTCTTACGGAAATGAAAAACGattTTTTTGCCCTCCTCCTTGTGTGTATCTTATGGGCAGtggttggaagaaaaaaaaagagcaaatggAACGAGATGGATGTTCTGAACAAGAGTCTCAACCCTGTGCGTTTATTGGAATAGGAAACAGTGACCAAGAAATGCAGCAGCTGAACTTGGAAGGGAAGAACTACTGTACAGCCAAAACATTGTACATATCTGATTCAGACAAGAGAAAACATTTCATGTTGTCTGTAAAGATGTTCTATGGCAACAGCGATGACATTGGTGTGTTCCTCAGCAAGCGGATAAAGGTCATCTCCAAACCCTCCAAAAAGAAGCAGTCACTGAAGAATGCTGACTTGTGCATTGCTTCAGGAACGAAGGTGGCACTGTTCAATCGCCTTCGGTCCCAGACAGTTAGTACCAGGTACCTGCATGTAGAAGGAGGGAATTTCCACGCCAGTTCACAACAGTGGGGAGCATTTTACATCCATCTCTTGGACGACGACGAGTCGGAAGGAGAGGAGTTCACAGTTAGAGATGGCTACATCCATTACGGGCAGACTGTCAAGCTTGTGTGCTCAGTGACTGGCATGGCACTCCCAAGATTGATAATTAGGAAAGTTGATAAGCAGACGGCATTACTGGATGCAGACGACCCTGTATCACAACTCCACAAATGTGCATTTTACCTTAAGGATACAGAAAGAATGTACTTGTGCCTTTCTCAAGAAAGAATAATCCAATTTCAGGCCACTCCATGtccaaaagaacaaaataaggAAATGATAAACGATGGAGCTTCCTGGACAATCATTAGCACAGACAAGGCCGAGTACACGTTCTATGAGGGAATGGGCCCCGTCCTTGCCCCAGTCACCCCTGTGCCTGTCGTAGAAAGTCTTCAGatgtggagagaGCATGCTCTGTGTGGTCCCAGACATTTCTGCATTCCGGGAAGGTTGGAGATGGGTCCGCCAGCCAGTCCAGGTTCCAGTGACTTTGGTCCGAAATGACGGGGTCATTTACTCCACCAGCCTTACCTTCACCTACACACCAGAGCCAGGGCCGAGGCCACACTGCAGCGCTGCAGGAGCGATTCTCAGAGCCAACTCCAGCCAAGTGCCCTCCAATGAGTCAAACACAAACAGCGAGGGGAattacacaaatgccagcacaaaTTCTACCAGTGTCACATCGTCCACAGCAACCGTGGTGTCCTAACTACCGTCTTTTTGCTGGGACTGAAACTGACTTGAATGCAGCAAAAAGTTGACAGAGAAAGGCAAGGATAAAGTGAACAATCTTTTGTGGTTTCTTGGGGAAACGTTTCGTACCAGGTGATCTATTCAAAACTGCCAGTGCAGGTGTGACATGCAGAGGCCACAGTACAATGAACAACATCAGAATGCACAGGCTGATGGAAATCCAGGTTTTCAGCTGTCCCTCTCACACGCACccctttttggttgttttggtttggttttgatttaatGGCCAGGAAACAGatatgtggctggagcacaggctAAGCTAGAAGACACAAACCTAACATAGACTTATGGACCAAGGGACTCGCATAAGCTTTAGTGAAAGGTACATTTTCACCATGCCTTTTTTATATCACAGTGTGTACTACACCTTGTTACCAAACAGGTTGCGCTCCCCACCCTTTGAGGGTTGGCTCTAAAGTACATTCATTCAGGTTCGAGCCTCACCATGTTTGTTCAGTCTGAACACTGAACACTTCCAGGTTCTTGTGGTCTAAGGCTGGAACTTTTTTAAGCTGAAGTCTTATGACTTTTTCATAAGTTGGAATTATTTTGATTTCAGCAAGTCAAATTTTGTAAAGGCCtgcatattttttttaagattatatgaAGTCTGCAAAAGCTTTAAAAATGCCTCTGCCTTGCCTGCAATACATGCAATGTGTGTTAACTGAGTCTGTTCTCAGAATCTGTTGGTAGTTATTTCtgtgttttccctttttttaaagaaatgtatttatagTGGTAATCTAAGAGATGCTAACAGCTCCGTGTGGCCATTTAGCCCTTTCTGAGTTCATGGCAGTGAGCACTGCCGTTCGAAGGCTGTGCGCCTCTGCCTGTTCATCAGTTCATCTGTGTTCCAGGATTTGTTCAGGTTTCCCCTTCCCCCAAATCTTGTACATAACTTGTATTAtgtgtaagttaaacattttaTCTTTACTTGGAATGTTCCCAGTGATTACATTTCACAGGGTGTTTCCCACCTTGTTGGCAAATGACAAAAAATATCATGCGAATTATTTGCTACCAAGATGGTGCCCGTAGGGTAAAATGAGGAACATCTCTGCAGGATGATTTAttgtatgttttcctttttttttagccTAGCCAGAACATCATTATAATTTTAAAGACCATAAGATGGCTTTTATTAGATGATAACTAAATAAACTGAACTAAGTAGCCAGAAGACAGTACCTTAGAGACTGATAGTTGTAagtttataaaaatacaaatgtaacttatatttccattttcctcTTTGCCCCTTTGTTTATTTTCCCCAGTAGAAATGTTCtgtccagatttttttccccctttttagtTAAGCCTTGCTTGCATTCAGGCTTGTGTGTCAGCCCTGTGTGCCAATATGCCAGATTCATTTTGTTTCCATCCCTGCACTTTGGTTATTCCTTGTTCAGTTTCTTGGGAATTGAAGCAGACTCATTGGGCTACATTTAGTACAAGAACCACATGTGTGATGTTAAAGGACACAGTCTAGTGATGCCATCATCCTTGAGTAAAAACTACCTCTAGATTGTGGTAAGCTTTTACTGTCCCTTAAAACAGGAGCCACTAGTACCTTATGAATGCAGACTGTAACTTCTATGGCATTTTCTGGTGTCTTtctggctctctgggcttctgAAAGTTTTCACGTAGACCCTTAGACTCCTCTGTCAGGACCATTGCTTTCCAGCGTTGCTGCTTTCACTCGCTGTCTCGAAGACTGTACCACTGTAAGTGCCACTGCGAACATCTTTAAACGGCTCCTCCTTGGCTTGTCAAGGGGAAGGCCACCTGTAAGATGTGGTGGTGACAGCCTTCCTGTCCACCCCAGGCTGCTCCTTACCAGCTGTTCTAGCCGATTCTCTTCAGATCAGCTACAGCCCACCTCCTCCCCGCCCCGCCTCACCCCTCCAGGCTGTCTCAGTGGTCCAGGGCAGAGCTCACTGTGGCCTTACTGATCTATCTCTGCAGTAACTGTTCTCCCTCAGTTGCGATGGAAGCAGGCCCCTGCGATCTGTTCAGAGCCTGAGCAGTTTGCAGTTCCGTTGTGCTTTCTGAGGTCCTAGATTCAGGATGTAGTTAAGTCGATAACTGAGAACAGATGAGATGCTTTTAAAGAACAAACTCTTCCTTACCCAGCTTTGTAGCTTAAAGTAAGTTTTCAAGTTCATGGCTTTATTAAAATGaactttgactttttaaaatgcttataTCTCATTTcggttcttttgtttattttagtaaGAATTGAAACAGACTATAAGtagttttcctgtttgtttgtttgtttgtttgttttttacaaagtTCAAGAATGTAACAATAAAGGCATTTTGCTATGGTTCTATGTCAGACTCCTACCACAGAATAGTGTGAACAGATATGTCTGTCTGCTTTACCATGTTATTGATAGTTCTTTTGTCAGCTGCTTTTATTAAAAGTCCTCTTTTGTGAATTTGTAAATCAATTTCAATATATGATGTACAGGAGTCTTGTCCCCCGTTACTGTGGAATGTTCCCCCCTGTTGATGCTGGTCCCTTTATCCTCTTATCTTCTTAGAACCGGGAATTCTTCAGTTGTGGTGTGTGGCTGTATTTTTCTATTCTGTTTACAGTGCGTCTACACAGCTTCTTAAAACATGTCGAAATGCAGAATCCAAGATCCACCATGAATTTGTCAAGAGATTGGAAGGCAGGCCAAAACCTGAAAATGTGGGGTGCCCTTTGTACAATTGCAGAGTCAAGCACTAGTGGGAGTTTGAACTGGCTACTGACCGCTCTTAAACTGTGGCAGTGTCCTTGGGTACAGTTAACTAGCAGAACCTGCTGTCACTCTTCCTGCCACCATCTTAACCTTgacagttttgtttcttttctgtgtggTGCTGGGGTCAAATCCAGAGCCTTAGGCTTGCtaaggctttttgtttgtttgatttttccttGAGACAAGTGTCTCACCCATGGAGCCCCTCAGCATTCTTGAAAGTCTCTGCCTTAGCCTCCAGGTCCTGTGGTACCAGGTGTGGCAGGATGCTTTTGTCATTAGAGAAACTGGTCTGTGTCCAACCACAGAAAAATTCCAATGCAGTTTTTAATAATTAATCCACTAGTTATTTAATCAAAATCTTTTTGTAGGGAGAGattcctgtttgaaagaaaatgCTATTTGATTATTAACCAAGGTAACAGACACTGCTTTCCAAAGCAGCTGTGTTTCTGGTGAGTACTGAAcaaatgtgtggttttctgtgCCACCTTTGATTCATTTTTCAAGCACTGTTACTCGGGATGGATGGTTAGAAACATGATATTTTAGTGTTTCTACTTAACCCTTTCAGGACCGAGCTGTATTGCCTTTCTATTAATTTCCCCCTGTGTTGTGATAAATGTTTGCTCGTGTTCAGTCCTGTGTCAGTCCAGACGTAGGTTTGTGTAAAAGCTCAGTTGTAGCTTATTTCTTGTACCTTGCAGCATGTTCTACGCATCCAGTCCTTAAGGGGTTTACTCTACAAACTGTGCACCTGCGTGTAAGGGTCATTAGCAATAAGATAGAAAATTGAGCAAGTTTATACCATAATTTTGTAGAAAAAGGAATCTGCTCAATTCCATATTTCATCCATGAAAACTCTGCAATACGGGCAGTTTCtaggaataaataaaaaggagatgCAAACCATTGTAGATGTCTTCTGTGGGATGTGCCCGATGCGTGCATCATCGTCTTTGATTCCAGGTACTtcataaagataaaattaaattc