Summary

Gene Name	Hspa8
Specie	Rattus norvegicus
Full Name	heat shock protein family A (Hsp70) member 8
Also known as	Hsc70
Coordinate	chr8:44989401-44993261
Strand	+
Gene summary	Enables several functions, including A1 adenosine receptor binding activity; ATP hydrolysis activity; and adenyl ribonucleotide binding activity. Involved in several processes, including animal organ development; protein import; and protein-containing complex disassembly. Acts upstream of or within cellular protein complex disassembly. Located in several cellular components, including dendrite; polymeric cytoskeletal fiber; and vacuole. Part of messenger ribonucleoprotein complex. Is active in several cellular components, including glutamatergic synapse; glycinergic synapse; and postsynaptic density. Biomarker of Parkinson's disease; acute kidney failure; brain ischemia; disease of metabolism; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Parkinson's disease and renal hypertension. Orthologous to human HSPA8 (heat shock protein family A (Hsp70) member 8). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Hspa8

Retroname	Coord	Strand	Genomic Region	ENSG
Hspa8P1	chr1:107826771-107828143	+	Intergenic	N/A	UCSC
Hspa8P2	chr1:127766489-127768350	-	Intragenic	N/A	UCSC
Hspa8P3	chr1:269557609-269559711	-	Intergenic	N/A	UCSC
Hspa8P4	chr2:107917498-107919568	+	Intergenic	N/A	UCSC
Hspa8P5	chr2:133460721-133462789	-	Intergenic	N/A	UCSC
Hspa8P6	chr2:137712114-137714069	+	Intergenic	N/A	UCSC
Hspa8P7	chr2:177651250-177653336	+	Intergenic	N/A	UCSC
Hspa8P8	chr2:226105695-226109691	+	Intergenic	N/A	UCSC
Hspa8P9	chr2:229131727-229133816	-	Intergenic	N/A	UCSC
Hspa8P10	chr2:244246439-244248496	-	Intergenic	N/A	UCSC
Hspa8P11	chr2:91065532-91067571	+	Intergenic	N/A	UCSC
Hspa8P12	chr3:134543934-134546013	-	Intergenic	N/A	UCSC
Hspa8P13	chr3:550025-554440	+	Intergenic	N/A	UCSC
Hspa8P14	chr3:64996743-64998848	-	Intergenic	N/A	UCSC
Hspa8P15	chr3:70678736-70680484	-	Intergenic	N/A	UCSC
Hspa8P16	chr5:38360246-38361448	+	Intergenic	N/A	UCSC
Hspa8P17	chr5:55800797-55802900	+	Intergenic	N/A	UCSC
Hspa8P18	chr5:65250688-65252750	-	Intergenic	N/A	UCSC
Hspa8P19	chr5:84571404-84573950	+	Intergenic	N/A	UCSC
Hspa8P20	chr5:99031007-99033110	-	Intergenic	N/A	UCSC
Hspa8P21	chr6:136653048-136653361	-	Intergenic	N/A	UCSC
Hspa8P22	chr6:34553287-34555386	-	Intergenic	N/A	UCSC
Hspa8P23	chr6:99434874-99435431	+	Intergenic	N/A	UCSC
Hspa8P24	chr7:105824007-105825767	-	Intergenic	N/A	UCSC
Hspa8P25	chr8:2202773-2204788	+	Intergenic	N/A	UCSC
Hspa8P26	chr11:13499163-13501263	+	Intergenic	N/A	UCSC
Hspa8P27	chr11:17336385-17337564	-	Intergenic	N/A	UCSC
Hspa8P28	chr11:85168672-85170733	-	Intergenic	N/A	UCSC
Hspa8P29	chr13:18079956-18082051	+	Intergenic	N/A	UCSC
Hspa8P30	chr14:107940171-107942287	+	Intergenic	N/A	UCSC
Hspa8P31	chr16:18381714-18389142	+	Intergenic	N/A	UCSC
Hspa8P32	chr16:2507111-2508277	-	Intragenic	N/A	UCSC
Hspa8P33	chr16:34210430-34211328	-	Intergenic	N/A	UCSC
Hspa8P34	chr16:35469442-35471491	-	Intragenic	N/A	UCSC
Hspa8P35	chr17:55020749-55022669	+	Intragenic	N/A	UCSC
Hspa8P36	chr17:60734360-60736522	+	Intergenic	N/A	UCSC
Hspa8P37	chr17:67433483-67435532	+	Intergenic	N/A	UCSC
Hspa8P38	chr18:17116471-17118570	+	Intragenic	N/A	UCSC
Hspa8P39	chr18:23566710-23568735	+	Intergenic	N/A	UCSC
Hspa8P40	chr18:48994516-48996609	-	Intergenic	N/A	UCSC
Hspa8P41	chr20:26529519-26531440	+	Intragenic	N/A	UCSC
Hspa8P42	chr20:32540716-32542471	+	Intragenic	N/A	UCSC
Hspa8P43	chr20:49193507-49195461	-	Intergenic	N/A	UCSC
Hspa8P44	chrX:131706408-131708638	+	Intergenic	N/A	UCSC
Hspa8P45	chrX:34295221-34297323	-	Intergenic	N/A	UCSC

Expression

Transcript Sequences

>NM_024351.2

CTCATTGAACGCGGAGCCAGCTCTCGGGGGTCTCTGTGTGGTCTCGTCATCAGCACAGCTGGGCCTACACGCAAGCAACCATGTCTAAGGGACCTGCAGTTGGCATTGATCTTGGCACCACCTACTCCTGTGTGGGTGTCTTCCAGCATGGAAAGGTGGAAATAATTGCCAATGACCAGGGTAACCGCACCACGCCGAGCTATGTTGCTTTCACCGACACAGAACGATTAATTGGGGATGCGGCCAAGAATCAGGTTGCAATGAACCCCACCAACACAGTTTTTGATGCCAAACGTCTGATCGGACGTAGGTTCGATGATGCTGTTGTTCAGTCTGACATGAAGCACTGGCCCTTCATGGTGGTGAACGATGCAGGCAGGCCCAAGGTCCAAGTCGAATACAAAGGGGAGACAAAAAGTTTCTATCCTGAGGAAGTGTCTTCAATGGTTCTGACAAAAATGAAGGAAATTGCAGAAGCTTACCTTGGAAAGACTGTTACCAATGCCGTGGTCACCGTGCCAGCTTACTTCAATGACTCTCAGCGACAGGCAACAAAAGATGCTGGAACTATTGCTGGCCTCAACGTACTTCGAATTATCAATGAGCCAACTGCTGCTGCTATTGCCTATGGCTTAGATAAGAAGGTTGGGGCTGAAAGGAATGTGCTCATTTTTGACTTGGGAGGTGGCACTTTTGATGTGTCAATCCTCACTATCGAGGATGGAATTTTTGAAGTCAAATCAACAGCTGGAGACACCCACTTGGGTGGAGAAGACTTTGACAACCGAATGGTCAACCATTTCACTGCTGAGTTTAAGCGAAAGCACAAGAAGGACATCAGTGAGAATAAGAGAGCTGTCAGGCGTCTCCGCACTGCCTGTGAGCGGGCCAAGCACATCTCCTCCAGCACCCAGGCCAGTATTGAGATTGATTCTCTCTATGAGGGAATTGACTTCTACACCTCCATTACCCGTGCTCGATTTGAGGAGTTGAATGCTGACCTGTTCCGTGGCACACTGGACCCTGTAGAGAAGGCCCTTCGAGATGCCAAACTAGACAAGTCACAGATCCATGATATTGTCCTGGTGGGTGGTTCTACCAGAATCCCCAAGATCCAGAAACTTCTGCAAGACTTCTTCAATGGAAAAGAGCTGAATAAGAGCATTAACCCCGATGAAGCTGTTGCCTATGGTGCAGCTGTCCAGGCAGCCATTCTATCTGGAGACAAGTCTGAGAATGTTCAGGATTTGCTGCTCTTGGATGTCACTCCTCTTTCCCTTGGGATTGAAACTGCTGGTGGAGTCATGACTGTCCTCATCAAGCGCAATACCACCATTCCCACCAAGCAGACCCAGACTTTCACCACCTACTCTGACAACCAGCCAGGTGTACTCATCCAGGTGTATGAAGGTGAAAGGGCCATGACCAAGGACAACAACCTGCTTGGGAAGTTTGAGCTCACAGGCATACCTCCAGCACCCCGTGGGGTTCCTCAGATTGAGGTTACTTTTGACATTGATGCCAATGGCATCCTCAATGTTTCTGCTGTAGATAAGAGCACAGGAAAGGAGAACAAGATCACCATCACCAATGACAAGGGCCGCTTGAGTAAGGAGGATATTGAGCGCATGGTCCAAGAAGCTGAGAAGTACAAAGCTGAGGATGAGAAGCAGAGAGATAAGGTTTCCTCTAAGAACTCGCTGGAGTCTTATGCTTTCAACATGAAAGCAACTGTTGAGGATGAGAAACTTCAAGGCAAGATCAATGATGAAGACAAACAGAAGATTCTTGACAAGTGCAACGAAATCATCAGCTGGCTGGATAAGAACCAGACTGCGGAGAAGGAAGAATTTGAGCATCAGCAGAAAGAACTGGAGAAGGTCTGCAACCCTATCATCACCAAGCTGTACCAGAGTGCTGGTGGCATGCCTGGAGGAATGCCTGGTGGCTTCCCTGGTGGAGGAGCTCCTCCATCTGGTGGTGCTTCTTCAGGCCCCACCATTGAAGAGGTCGATTAAGTCAAAGTAGAGGGTATAGCATTGTTCCACAGGGACCCAAAACAAGTAACATGGAATAATAAAACTATTTAAATTGGCACCA