| Retrocopy Name | Hspa8P23 |
|
| Species | Rattus norvegicus | |
| Coordinates | chr6:99434874-99435431 UCSC | |
| Strand | + | |
| Parental Sequence | NM_024351.2 | |
| Parental seq. overlap | 449 bp | |
| Parental seq. overlap (%) | 21.3% | |
| Genomic Region |
Intergenic |
|
| Retrocopy Summary | Hspa8P23, located on chr6:99434874-99435431, is a retrocopy of the parental gene Hspa8. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | Hspa8 |
| Full Name | heat shock protein family A (Hsp70) member 8 |
| Also known as | Hsc70 |
| Coordinate | chr8:44989401-44993261 |
| Strand | + |
| Gene summary | Enables several functions, including A1 adenosine receptor binding activity; ATP hydrolysis activity; and adenyl ribonucleotide binding activity. Involved in several processes, including animal organ development; protein import; and protein-containing complex disassembly. Acts upstream of or within cellular protein complex disassembly. Located in several cellular components, including dendrite; polymeric cytoskeletal fiber; and vacuole. Part of messenger ribonucleoprotein complex. Is active in several cellular components, including glutamatergic synapse; glycinergic synapse; and postsynaptic density. Biomarker of Parkinson's disease; acute kidney failure; brain ischemia; disease of metabolism; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Parkinson's disease and renal hypertension. Orthologous to human HSPA8 (heat shock protein family A (Hsp70) member 8). [provided by Alliance of Genome Resources, Apr 2022] |
| Species | Scientific Name | Retrocopy | |
 |
Orangutan | Pongo abelii | HSPA8P12 |
 |
Gibbon | Nomascus leucogenys | HSPA8P1 |
 |
Green monkey | Chlorocebus sabaeus | HSPA8P11 |
 |
Crab-eating macaque | Macaca fascicularis | LOC101925240P2 |
 |
Rhesus | Macaca mulatta | HSPA8P8 |
 |
Baboon | Papio anubis | HSPA8P8 |
 |
Golden snub-nosed monkey | Rhinopithecus roxellana | HSPA8P6 |
 |
Marmoset | Callithrix jacchus | HSPA8P12 |
 |
Chinese hamster | Cricetulus griseus | Hspa8_1P1 |
 |
Rabbit | Oryctolagus cuniculus | HSPA8P11 |
 |
Pig | Sus scrofa | HSPA8P4 |
 |
Cow | Bos taurus | HSPA8P5 |
 |
Dolphin | Tursiops truncatus | HSPA8P3 |
 |
Horse | Equus caballus | HSPA8P7 |
 |
Panda | Ailuropoda melanoleuca | HSPA8P6 |
 |
Cat | Felis catus | HSPA8P5 |
 |
Pale spear-nosed bat | Phyllostomus discolor | HSPA8P1 |
 |
Velvety free-tailed bat | Molossus molossus | HSPA8P2 |
 |
Greater mouse-eared bat | Myotis myotis | HSPA8P3 |
 |
Kuhl's pipistrelle | Pipistrellus kuhlii | HSPA8P3 |
 |
Greater horseshoe bat | Rhinolophus ferrumequinum | HSPA8P15 |
 |
Sloth | Choloepus didactylus | HSPA8P4 |
 |
Human | Homo sapiens | Without Homology |
 |
Chimpanzee | Pan troglodytes | Without Homology |
 |
Bonobo | Pan paniscus | Without Homology |
 |
Gorilla | Gorilla gorilla | Without Homology |
 |
Mouse lemur | Microcebus murinus | Without Homology |
 |
Mouse | Mus musculus | Without Homology |
 |
Sheep | Ovis aries | Without Homology |
 |
Dog | Canis familiaris | Without Homology |
 |
Egyptian rousette | Rousettus aegyptiacus | Without Homology |
 |
Tasmanian Devil | Sarcophilus harrisii | Without Homology |
 |
Opossum | Monodelphis domestica | Without Homology |
 |
Platypus | Ornithorhynchus anatinus | Without Homology |
 |
Chicken | Gallus gallus | Without Homology |
 |
Turkey | Meleagris gallopavo | Without Homology |
 |
Zebra Finch | Taeniopygia guttata | Without Homology |
 |
Budgerigar | Melopsittacus undulatus | Without Homology |
 |
Painted Turtle | Chrysemys picta | Without Homology |
 |
Lizard | Anolis Carolinensis | Without Homology |
 |
Frog | Xenopus tropicalis | Without Homology |
 |
Zebrafish | Danio rerio | Without Homology |
 |
Drosophila | Drosophila melanogaster | Without Homology |
| >Hspa8P23 |
| CGATGCCAAGCTAGACAAGGGCCAGATCCAGGAGATAGTGCTGGTGGGCGGCTCTACCCGCATCCCTAAGATCCAGAAGCTCCTGCAGGATTTCTTCAACGGCAAGGAGCTGAACAAGAGCATCAATCCCGACGAGGCGGTGGCCTACGGCGCCGCCGTGCAGGCGGCTATCCTCATTGGCGACAAGTCTGAGAACGTGCAGGATCTGCTGTTACTCGACGTGACTCCCTTGTCGCTTGGCATTGAAACAGCTGGCGGTGTCATGACCCCACTCATAAAGAGAAACACCACCATCCCTACCAAGCAGACGCAGACCTTCACTACCTACTCAGACAACCAGAGCAGCGTGCTGGTGCAAGTGTACGAGGGCGAACGGGCCATGACCAAGGACAATAACCTCTTGGGCAAGTTCGACCTAACTGGGATCCCTCCAGCACCCCGCGGGGTCCCCCAGATCGAGGTCACCTTTGACATCGATGCCAACGGCATTCTTAACGTCACTGCTGCAGACAAGAGCACCGGCAAAGAAAATAAAATCACCATCACCAACGACAAGGG |
| >NM_024351.2 |
| CTCATTGAACGCGGAGCCAGCTCTCGGGGGTCTCTGTGTGGTCTCGTCATCAGCACAGCTGGGCCTACACGCAAGCAACCATGTCTAAGGGACCTGCAGTTGGCATTGATCTTGGCACCACCTACTCCTGTGTGGGTGTCTTCCAGCATGGAAAGGTGGAAATAATTGCCAATGACCAGGGTAACCGCACCACGCCGAGCTATGTTGCTTTCACCGACACAGAACGATTAATTGGGGATGCGGCCAAGAATCAGGTTGCAATGAACCCCACCAACACAGTTTTTGATGCCAAACGTCTGATCGGACGTAGGTTCGATGATGCTGTTGTTCAGTCTGACATGAAGCACTGGCCCTTCATGGTGGTGAACGATGCAGGCAGGCCCAAGGTCCAAGTCGAATACAAAGGGGAGACAAAAAGTTTCTATCCTGAGGAAGTGTCTTCAATGGTTCTGACAAAAATGAAGGAAATTGCAGAAGCTTACCTTGGAAAGACTGTTACCAATGCCGTGGTCACCGTGCCAGCTTACTTCAATGACTCTCAGCGACAGGCAACAAAAGATGCTGGAACTATTGCTGGCCTCAACGTACTTCGAATTATCAATGAGCCAACTGCTGCTGCTATTGCCTATGGCTTAGATAAGAAGGTTGGGGCTGAAAGGAATGTGCTCATTTTTGACTTGGGAGGTGGCACTTTTGATGTGTCAATCCTCACTATCGAGGATGGAATTTTTGAAGTCAAATCAACAGCTGGAGACACCCACTTGGGTGGAGAAGACTTTGACAACCGAATGGTCAACCATTTCACTGCTGAGTTTAAGCGAAAGCACAAGAAGGACATCAGTGAGAATAAGAGAGCTGTCAGGCGTCTCCGCACTGCCTGTGAGCGGGCCAAGCACATCTCCTCCAGCACCCAGGCCAGTATTGAGATTGATTCTCTCTATGAGGGAATTGACTTCTACACCTCCATTACCCGTGCTCGATTTGAGGAGTTGAATGCTGACCTGTTCCGTGGCACACTGGACCCTGTAGAGAAGGCCCTTCGAGATGCCAAACTAGACAAGTCACAGATCCATGATATTGTCCTGGTGGGTGGTTCTACCAGAATCCCCAAGATCCAGAAACTTCTGCAAGACTTCTTCAATGGAAAAGAGCTGAATAAGAGCATTAACCCCGATGAAGCTGTTGCCTATGGTGCAGCTGTCCAGGCAGCCATTCTATCTGGAGACAAGTCTGAGAATGTTCAGGATTTGCTGCTCTTGGATGTCACTCCTCTTTCCCTTGGGATTGAAACTGCTGGTGGAGTCATGACTGTCCTCATCAAGCGCAATACCACCATTCCCACCAAGCAGACCCAGACTTTCACCACCTACTCTGACAACCAGCCAGGTGTACTCATCCAGGTGTATGAAGGTGAAAGGGCCATGACCAAGGACAACAACCTGCTTGGGAAGTTTGAGCTCACAGGCATACCTCCAGCACCCCGTGGGGTTCCTCAGATTGAGGTTACTTTTGACATTGATGCCAATGGCATCCTCAATGTTTCTGCTGTAGATAAGAGCACAGGAAAGGAGAACAAGATCACCATCACCAATGACAAGGGCCGCTTGAGTAAGGAGGATATTGAGCGCATGGTCCAAGAAGCTGAGAAGTACAAAGCTGAGGATGAGAAGCAGAGAGATAAGGTTTCCTCTAAGAACTCGCTGGAGTCTTATGCTTTCAACATGAAAGCAACTGTTGAGGATGAGAAACTTCAAGGCAAGATCAATGATGAAGACAAACAGAAGATTCTTGACAAGTGCAACGAAATCATCAGCTGGCTGGATAAGAACCAGACTGCGGAGAAGGAAGAATTTGAGCATCAGCAGAAAGAACTGGAGAAGGTCTGCAACCCTATCATCACCAAGCTGTACCAGAGTGCTGGTGGCATGCCTGGAGGAATGCCTGGTGGCTTCCCTGGTGGAGGAGCTCCTCCATCTGGTGGTGCTTCTTCAGGCCCCACCATTGAAGAGGTCGATTAAGTCAAAGTAGAGGGTATAGCATTGTTCCACAGGGACCCAAAACAAGTAACATGGAATAATAAAACTATTTAAATTGGCACCA |
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