| Gene Name | Vcp |
|
| Specie | Mus musculus | |
| Full Name | valosin containing protein | |
| Also known as | 3110001E05|CDC48|p97|p97/VCP | |
| Coordinate | chr4:42979964-43000507 | |
| Strand | - | |
| Gene summary | Enables several functions, including ATP hydrolysis activity; K48-linked polyubiquitin modification-dependent protein binding activity; and adenyl ribonucleotide binding activity. Involved in ATP metabolic process; positive regulation of mitochondrial membrane potential; and proteasomal protein catabolic process. Acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process; aggresome assembly; and ubiquitin-dependent protein catabolic process. Located in endoplasmic reticulum membrane and synapse. Part of ATPase complex; VCP-NSFL1C complex; and endoplasmic reticulum membrane. Is expressed in several structures, including cerebral cortex; early embryo; gonad; gut; and triceps surae muscle. Used to study inclusion body myopathy with Paget disease of bone and frontotemporal dementia. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y; Paget's disease of bone; amyotrophic lateral sclerosis type 14; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1; and inclusion body myositis. Orthologous to human VCP (valosin containing protein). [provided by Alliance of Genome Resources, Apr 2022] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| VcpP1 | chrX:103388873-103392111 | - |
Intragenic |
ENSMUSG00000083327 | UCSC |
| >NM_009503.4 |
| GAGTCCCAAGGCCGGCGCTGATTGGTTGGGGTTAGAGCAGCTTTCCTTCCGATGATTCGGCTTTTCTCGGTTCAGTCTCCGTGAAGCGTTTGCAGCCGTCGTTTGATTAGTCGCTGCCCCCCTCGCGGATTAGGAGCTAGCGTctcccgcccgcccgcctgccGCCCCGGTGCCCCTGGGAGGAAGCGAGAGGGAGGCTGCCAGAGGGTTTGTCACTGCTGTTGCTCCTCCGCCTCAGCGAGTCCAGCCCCGGCCTAGTCGGTCGCCTGCCTTTCTCATAGCCGTTACCCTCAGGCCGCCACAGCCGCCGACCGGGAGAGGCGCGCGCCATGGCCTCTGGAGCCGATTCAAAAGGTGATGATTTATCAACAGCCATTCTCAAACAGAAGAACCGACCCAATCGGTTAATTGTTGATGAAGCCATCAATGAAGATAACAGCGTGGTGTCCTTGTCCCAGcCCAAGATGGATGAACTGCAGTTGTTCCGAGGTGACACGGTGTtgctaaaaggaaagaaaagacggGAAGCTGTATGCATTGTTCTTTCTGATGACACGTGTTCTGATGAGAAGATTCGAATGAATAGAGTTGTTCGGAATAACCTCCGAGTTCGCCTAGGAGATGTCATCAGCATCCAGCCATGCCCTGATGTAAAGTATGGCAAACGTATCCACGTTCTACCCATCGATGACACAGTGGAAGGCATCACTGGCAATCTCTTTGAGGTATACCTTAAGCCGTACTTCCTGGAAGCTTATCGGCCCATCCGTAAAGGAGATATTTTTCTTGTCCGGGGTGGGATGCGTGCTGTGGAGTTCAAAGTTGTAGAGACAGATCCCAGCCCTTACTGTATTGTTGCTCCAGACACAGTGATCCACTGTGAGGGGGAGCCAATCAAGCGAGAGGATGAGGAGGAATCCTTGAATGAAGTAGGCTATGATGACATCGGTGGTTGCAGGAAGCAGCTAGCTCAGATAAAGGAGATGGTGGAGCTGCCACTGAGACATCCTGCGCTCTTTAAGGCGATTGGTGTAAAGCCTCCTCGGGGAATCTTGTTGTATGGGCCTCCTGGGACAGGGAAGACCCTGATTGCTCGAGCTGTGGCAAATGAAACTGGAGCCTTCTTCTTTCTGATCAATGGTCCTGAAATCATGAGCAAATTGGCTGGTGAGTCTGAGAGCAACCTTCGTAAAGCCTTTGAGGAAGCTGAAAAGAATGCTCCTGCTATCATCTTCATCGATGAGCTTGATGCCATTGCACCCAAAAGAGAGAAAACTCATGGGGAAGTGGAGCGTCGCATCGTGTCTCAGTTGTTGACCCTCATGGATGGCCTAAAGCAGAGAGCACATGTGATAGTTATGGCAGCAACCAATAGACCCAACAGCATTGACCCAGCCCTACGGCGATTTGGTCGCTTTGACAGAGAGGTAGATATTGGAATACCTGATGCTACAGGACGTTTGGAGATTCTTCAGATCCATACCAAGAACATGAAACTGGCAGATGATGTGGACTTGGAACAGGTAGCCAATGAGACTCATGGTCATGTTGGTGCTGATTTGGCAGCCCTATGTTCAGAGGCTGCTCTGCAGGCCATCCGGAAAAAAATGGACCTCATTGACCTAGAAGATGAGACCATTGATGCTGAGGTCATGAATTCCCTGGCAGTTACTATGGATGACTTCCGGTGGGCTTTGAGTCAAAGCAACCCATCAGCACTTCGGGAAACTGTGGTAGAGGTGCCACAAGTAACCTGGGAAGATATTGGAGGCCTGGAGGATGTCAAACGTGAGCTTCAGGAGTTGGTTCAGTATCCTGTGGAACATCCAGACAAATTCCTCAAATTTGGCATGACTCCCTCCAAAGGCGTTCTTTTCTATGGACCTCCTGGCTGTGGGAAAACCTTACTGGCTAAAGCCATTGCTAATGAATGCCAGGCCAACTTCATCTCCATCAAGGGTCCTGAGCTGCTTACCATGTGGTTTGGGGAATCTGAGGCCAATGTCCGGGAAATTTTTGACAAGgcACGGCAAGCTGCCCCCTGTGTACTCTTCTTTGATGAGTTAGATTCAATTGCCAAGGCTCGAGGTGGTAATATTGGAGATGGTGGTGGAGCTGCTGACCGAGTCATCAATCAGATCCTGACAGAAATGGATGGCATGTCTACAAAAAAGAATGTGTTTATCATTGGAGCTACCAACAGGCCTGACATCATTGATCCTGCTATCCTAAGACCTGGCCGTCTAGATCAGCTCATTTATATCCCACTTCCTGATGAGAAGTCCCGTGTTGCCATCCTAAAAGCCAATCTGCGAAAGTCCCCAGTTGCCAAGGATGTGGATTTGGAGTTCCTGGCTAAGATGACTAATGGCTTTTCTGGAGCTGATTTGACAGAAATTTGCCAACGGGCTTGTAAACTGGCCATTCGTGAATCTATTGAGAGTGAGATTAGGCGAGAACGAGAGAGGCAGACAAATCCATCGGCTATGGAGGTAGAAGAGGACGATCCAGTGCCTGAGATCCGCAGAGATCACTTTGAGGAAGCCATGCGTTTTGCCCGACGTTCTGTCAGCGATAATGACATTCGGAAGTATGAAATGTTCGCCCAGACACTGCAGCAGAGTCGAGGTTTTGGCAGCTTCAGATTCCCTTCAGGGAACCAGGGTGGAGCTGGTCCCAGCCAGGGCAGTGGAGGTGGCACAGGTGGCAGTGTGTACACAGAAGACAATGACGATGACCTGTATGGCTAAGTGATGTGCCAGCATGCAGCGAGCTGGCCTGGCTGGACCTTGTTCCCTGGGGGAGGGGGCGCTTGCCCAAGAGGGACCAGGGGTGTGCCCATGGCCTGTTCCATTCCTCAGTCTGAACAGTTCAGCCCCAGTCAGACTCTGGACAGGGGTTtcctgttgcaaaaaaaaaaaattacaaaagcgataaaataaaagtgattttCATTTGGGAGGTGAAGAGTGAATTACCAGCAAGGAATTGGGTCTTGGGCCCACACGGTTTCTGTCGTAGTTTGGGGTGGTGCAGGTAACCTGTGTGGTGTGAACCAAGGCAttgccaccaccatcaccacagtaAAGCATCTATACTCAATGCTGTCCAAGTCCTCCCTTACCCTAGCCAACCTGGGTAGGTGGATGAGGGGCCTCAGTTTGCTGGGTGTTTATATAGAAAGtaggttgatttttattttacatgcttTTGAGTTACTGTTGGAAGATTAATCATAAGCAGTTtctaaaccaaaaaaaagaagaaaaaaaaaagacatgttgtAAAAGGACAATAAATGTTGGGTCAAAATGG |