| Gene Name | GLRX |
|
| Specie | Homo sapiens | |
| Full Name | glutaredoxin | |
| Also known as | GRX|GRX1 | |
| Coordinate | chr5:95813849-95822726 | |
| Strand | - | |
| Gene summary | This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| GLRXP2 | chr14:90107624-90108893 | + |
Intragenic |
ENSG00000258544 | UCSC |
| GLRXP1 | chr20:37601856-37603249 | - |
Intergenic |
ENSG00000228234 | UCSC |
| GLRXP3 | chr5:161750455-161751832 | - |
Intergenic |
ENSG00000118990 | UCSC |
| >NM_002064.3 |
| GCTCAATACCCCAAGCAATACCTGCAACTGAGGATTCTTCCCGGGGAGACCGCAGCCCATCGGCATGGCTCAAGAGTTTGTGAACTGCAAAATCCAGCCTGGGAAGGTGGTTGTGTTCATCAAGCCCACCTGCCCGTACTGCAGGAGGGCCCAAGAGATCCTCAGTCAATTGCCCATCAAACAAGGGCTTCTGGAATTTGTCGATATCACAGCCACCAACCACACTAACGAGATTCAAGATTATTTGCAACAGCTCACGGGAGCAAGAACGGTGCCTCGAGTCTTTATTGGTAAAGATTGTATAGGCGGATGCAGTGATCTAGTCTCTTTGCAACAGAGTGGGGAACTGCTGACGCGGCTAAAGCAGATTGGAGCTCTGCAGTAACCACAGAACAGGCCCCATGCTGACGTCCCTCCTCAAGAGCTGGATGGCATTGCAAATGATGACAGCACTTCTGGTGGATGAATTTGGGGGCACAAACAGCTTTTTTCCTCTTTTGGCTCAGTATTTAAAAGTGGACCAACTTGCTCTTAATCACAGGGCCAAGAAGGTTGACGGGCCATCTTGGTTTTCTTCTGGATGTGCTCTTTGGTTTTCAGAAGACTGTGACAAGTTCTGGCCCAGGATTCGCTCACTGACCCTCAATTGTCCTCTTTGGCATGCGTTTCTTACTGTTCTCCATGTGTCGGCATGTCTCTACCTCTAAGCCAGTGTTTTTCAACTATGTTTATCCAGACTCCTTCTCCACAATGATGAATCCACAGTTGGTTATCTGCTACTGCCCATTAGCTAAAATCATTTTGCTGCTTGACTTTATGGAGTTTGTATTATGAAATCAGTGGGTATTTTGAATGTGTTCTTTCTAACTACATGCATCTCTCCACTCAACTCCACCCCATCCCATCCCACCTTGAAAATCACTGCTCTGAACCAGTGTTCTCCACCTTGTCCTCCACAGATCTCATAGGAAATGTTCAACAATTCTGTGAAAGGTCACAGGACCCAATTGGAGAAATCATATGAAAAGCATAGTTGGTCTTGGTGTCATATGGATCAGAGGCACAAGTGCAGAGGCTGTGGtcatgcggaacactctgttatttaagatggctatccagataatcctgaacactgtgtatttattttatttagactaccagcaaagattaaagcatgaaatgtaaaacatctgataaaacttacagccccctacaccaagagtgtatctgtgaaAGAGCTCCTACACTTTGAAAACTTAAGAATCCCTTATCATGAAGTTTGCCTGTTCTAGAATTGTAAGATTGTTAATTTCCTTCAATCTCTAGTGACAACACTTAATTTCTTTTCTAATAAAAAAAACCTATAGATGATTCAGTGATTTTTGTCCAATTCATTTGCATGTTCTCAAGACATTAAGGAATGTTATGCGAAATACACTAACTTAAAACTGTGTTTATATTTGGCCCTGCCATTATAAATAAAGACACGTGCTGCTGTCA |