| Gene Name | GLUD1 |
|
| Specie | Homo sapiens | |
| Full Name | glutamate dehydrogenase 1 | |
| Also known as | GDH|GDH1|GLUD|hGDH1 | |
| Coordinate | chr10:87050202-87094843 | |
| Strand | - | |
| Gene summary | This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| GLUD1P4 | chr18:59778577-59779309 | + |
Intergenic |
ENSG00000267486 | UCSC |
| GLUD2 | chrX:121047613-121050605 | + |
Intergenic |
ENSG00000182890 | UCSC |
| >NM_001318901.1 |
| GTATATGCTGATCTTGCATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAATGCACTTCTAGGAAAGGGAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTATGCCCAGCTCTCTCCTGTTTTTATAAGTCGCAGCTCCGCAAACTCACTGAAGCAACTCGTTTACCATAGTTTTTACTACATGTACCTGAGGCCGTTAGATTTGTCTGTGTTAAGGATTTGAAAGGAGGCAGAAATTAATACAGATTCAAGTGTTCACTATCAAGTCGGAATTGTTAATATGTGAAATACTACTGTTAAAGGCAGGAAAGGCTTTATTAAGGACAAGAAGACAAACTAGGAGAAGGAGCTACTCAAGACCTTCCGATTATCTTTACAAAAAGGCAACTACACCTAGAAGATTCTGCAGCCACACACATTCTGCCTTCACTTGAGGTCAACTGCCTTCACCAAGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAGGGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTGGTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTGTTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATGGGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAAAGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCAGAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTATTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGACCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTATTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGGAGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGAAAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTCTGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATCCAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGATCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCCATTTTGGTATTTTGCCTTTAAATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAGTGCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACTGTAACTTTAACACATTTAAGAAGTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTTCTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTGCAAACAAATATAAAACCTGTTTCTGTTTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATCACTTAACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTATATCATAAAACAATGTCATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGGATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAGGCTATTTTCATTAAAACTGTCAGAATTTGCTTACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTGTTCTCTTTTGAAGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCCTGTTTGGAGTCTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTTTTAGAGGCTTTGCATTCTGCACCCAGCTTCACTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTTCATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAGTGCTAGATAATATATGTGTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTGCATGGCTTAACCTGGTGATAAAAGCAGTTATTAAAAGTCTACGTTTTCCAAAACTTACGTTTCTTTTCTGTGTTTTTACATGTGGTAGTTTCTCTTTTCATAAGTTATAATACTGCAATTGGATTTCTGAAATGTTTATAGCGACCACCTGTATAACATTTCCTTCCACTTTATTGTGAGCTGCCCAGATTTTATTCTTGAATTGTTTTTTTTTTTTTTGttcggtgctttacacgttcagagaaacttcccgagtaacgaactatagaaatgatccctgaaagcatagtcttTATTCTCGAATTATTTTGTATTTTATTAAATAATATGAACAGCT |
| >NM_005271.5 |
| CTCCCTAGTCGCGGGGAGTCTGAGAAAGCGCGCCTGTTTCGCGACCATCACGCACCTCCCCTCCGCTTGTGGCCATGTACCGCTACCTGGGCGAAGCGCTGTTGCTGTCCCGGGCCGGGCCCGCTGCCCTGGGCTCGGCGTCCGCCGACTCGGCCGCGTTGCTGGGCTGGGCCCGGGGACAGCCCGCCGCCGCCCCGCAGCCGGGGCTGGCATTGGCCGCCCGGCGCCACTACAGCGAGGCGGTGGCCGACCGCGAGGACGACCCCAACTTCTTCAAGATGGTGGAGGGCTTCTTCGATCGCGGCGCCAGCATCGTGGAGGACAAGCTGGTGGAGGACCTGAGGACCCGGGAGAGCGAGGAGCAGAAGCGGAACCGGGTGCGCGGCATCCTGCGGATCATCAAGCCCTGCAACCATGTGCTGAGTCTCTCCTTCCCCATCCGGCGCGACGACGGCTCCTGGGAGGTCATCGAAGGCTACCGGGCCCAGCACAGCCAGCACCGCACGCCCTGCAAGGGAGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAGGGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTGGTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTGTTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATGGGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAAAGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCAGAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTATTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGACCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTATTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGGAGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGAAAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTCTGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATCCAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGATCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCCATTTTGGTATTTTGCCTTTAAATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAGTGCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACTGTAACTTTAACACATTTAAGAAGTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTTCTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTGCAAACAAATATAAAACCTGTTTCTGTTTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATCACTTAACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTATATCATAAAACAATGTCATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGGATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAGGCTATTTTCATTAAAACTGTCAGAATTTGCTTACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTGTTCTCTTTTGAAGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCCTGTTTGGAGTCTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTTTTAGAGGCTTTGCATTCTGCACCCAGCTTCACTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTTCATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAGTGCTAGATAATATATGTGTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTGCATGGCTTAACCTGGTGATAAAAGCAGTTATTAAAAGTCTACGTTTTCCAAAACTTACGTTTCTTTTCTGTGTTTTTACATGTGGTAGTTTCTCTTTTCATAAGTTATAATACTGCAATTGGATTTCTGAAATGTTTATAGCGACCACCTGTATAACATTTCCTTCCACTTTATTGTGAGCTGCCCAGATTTTATTCTTGAATTGTTTTTTTTTTTTTTGttcggtgctttacacgttcagagaaacttcccgagtaacgaactatagaaatgatccctgaaagcatagtcttTATTCTCGAATTATTTTGTATTTTATTAAATAATATGAACAGCT |