| Gene Name | GLUL |
|
| Specie | Homo sapiens | |
| Full Name | glutamate-ammonia ligase | |
| Also known as | GLNS|GS|PIG43|PIG59 | |
| Coordinate | chr1:182378098-182391790 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| GLULP3 | chr11:122613325-122614690 | - |
Intergenic |
ENSG00000254572 | UCSC |
| GLULP8 | chr11:9957759-9959912 | - |
Intragenic |
ENSG00000254765 | UCSC |
| GLULP6 | chr2:194129354-194130297 | - |
Intergenic |
ENSG00000215043 | UCSC |
| GLULP7 | chr5:151848806-151850911 | + |
Intragenic |
ENSG00000270978 | UCSC |
| GLULP4 | chr9:34917044-34918405 | + |
Intragenic |
ENSG00000178723 | UCSC |
| >NM_001033044.4 |
| AGAGTCGAGAGTGGGAGAAGAGCGGAGCGTGTGAGCAGTACTGCGGCctcctctcctctcctaacctcgctctcGCGGCCTAGCTTTACCCGCCCGCCTGCTCGGCGACCAGAACACCTTCCACCATGACCACCTCAGCAAGTTCCCACTTAAATAAAGGCATCAAGCAGGTGTACATGTCCCTGCCTCAGGGTGAGAAAGTCCAGGCCATGTATATCTGGATCGATGGTACTGGAGAAGGACTGCGCTGCAAGACCCGGACCCTGGACAGTGAGCCCAAGTGTGTGGAAGAGTTGCCTGAGTGGAATTTCGATGGCTCTAGTACTTTACAGTCTGAGGGTTCCAACAGTGACATGTATCTCGTGCCTGCTGCCATGTTTCGGGACCCCTTCCGTAAGGACCCTAACAAGCTGGTGTTATGTGAAGTTTTCAAGTACAATCGAAGGCCTGCAGAGACCAATTTGAGGCACACCTGTAAACGGATAATGGACATGGTGAGCAACCAGCACCCCTGGTTTGGCATGGAGCAGGAGTATACCCTCATGGGGACAGATGGGCACCCCTTTGGTTGGCCTTCCAACGGCTTCCCAGGGCCCCAGGGTCCATATTACTGTGGTGTGGGAGCAGACAGAGCCTATGGCAGGGACATCGTGGAGGCCCATTACCGGGCCTGCTTGTATGCTGGAGTCAAGATTGCGGGGACTAATGCCGAGGTCATGCCTGCCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATGGGAGATCATCTCTGGGTGGCCCGTTTCATCTTGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCTGGGAACTGGAATGGTGCAGGCTGCCATACCAACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATTGAGAAACTAAGCAAGCGGCACCAGTACCACATCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCATGAAACCTCCAACATCAACGACTTTTCTGCTGGTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAGGGTTACTTTGAAGATCGTCGCCCCTCTGCCAACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACCGGCGATGAGCCCTTCCAGTACAAAAATTAAGTGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCCCCCTCTCCCAGTTGTCCCGATTGTAACTCAAAGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTTTGTTTGGCTGGGATAGAGGGGTCAAGTTATTAATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAGTGGGGAGGAGGGTGGGGAGACATAACCACTGCTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTTGCAGAAGGGGGTCTCTTCTTCCAGGTAGCTGAAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTTTTCTTAAAAAGTTATAACCAACTTTTCTATTAAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCTCTTGCTTGTGGGACTAGCCTGGCTTGGGACTAAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAAGAAGAAAAGGTTCTTACTGCTTGGTCCTTGATTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATATGTATGGTTTTGTGGATTATGTGTGTTTTGCTAAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGAAATAAAGCATCTCATTTTGAGTAGAGAGCAAGGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCTGCCCTGCCCACCCTCTGGAGAAGGTGGGCACTGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTTAAAAGACACACTTGTCCACATAGGTTTAGAGATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTTTCTGGTAGGAATAGCATGTCACTAAAGCAGGCCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAATTTGTAGGGTTTCTAGGTAATTTTTACAGAATTGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTGGAGTCAAAACACTTGTAATTTTGTATCTTGATGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCCCACCTTTATTCCTTCATTTCATCTACCATTTTCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTTCTAATTGCCATGTACAGTATGTTCAAAGTCAAATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGCCTAACATAAGATCTCTCTGATGTGTTTGTGATTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAGCTCAAGTTTATGTACTCTGAGTTTTTAAAACACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGACTTAAGGGATTAAGTTTTTCACCTAGACTTAGTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCACTCCTCCCCCTTCCTTTGCTCCCCTGAGTTTGGTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACATAATGTAAGATTAACTGGCTTTACGATTTCTATTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCCTTCCAAGGCTGGCTATGCCCTAGGCATGGGCTCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAAAGCTCTGTGTTGTCACCTGTGCCCTTGCCCCTTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCTACCTTCGTTCATTCCTCATGAGGTTGGGTAAAAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGACACATTGGAGTGCAATATTATTAATAGCATTAATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAGTGCGAGGTAGCTGGGGCCTGTGATAGTTTTTAGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCCGTGGTTTTTCTTAAGAAAGTTGGCTCGTAATATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTTTATGCCTGTTTCAGCATGATTGTTGAGTACCCTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCCATTGAATCTGTGCTTCCACCCCCCCAACTGAAGTTGTCTTCCCTTTGCTTGGCCACCCTTACAGCCTCTTGGATGGTGTATCCTACAGTGTAAGCACTAAACTGAAGAGGCAGTGACCTGAGCACTTTGGATTTTGTTCATTGTAATCAATTCCATGACAAAATGATTGCATGAGAAGGAATTTTAAATTCATAGGATCAGAATTTAGGTGAAAACAACCAGCATATTTGTTTCTTCACCCTCTCACCTAGAATTAGCTTTGACCTACAGGTCACAGTGCAATCCCCTTGTATTTCTAAGGTGTTTTTTATAGTTCATTTGCAGACAATGGGTTATGTGATAACTTTTATCAGTGATAGATTAAACAGAATAATGACCAAGCTTTCAACCTTAAGGAGTCAGGCCAGTATTTACAAAAGGAGGTCTCCATGAACTCCTTAAATATGAGTTCCCCTAATATCATCTTGCCAGGTACTAAATAACAACTGATAGCACAAGCTATAGGGAATTTGAAAGAATTCCATGGATGGGTGTTGTCTAGGGCCttttgttgtttttgagacggggtctgactctcacccaggctggagtatagtgtggcgcaatcttggctcactgcaacttctgcctcccagattcaagcgattctcctgcctcagcctcccaagtagctgagactacaggtgtgcaccaccatgctcagctaatttttgtatttttagtacagatggggtttcaccatgttggccaggctggtcttgaactcctgatctcccaaagtgaggtcttgaactggtcttgaactcctccacctcccaaagtgctgggattacaggcgtgagccactgcacccggccTAGGGCCATGTAAAAAGCCAGATCTGTGCTGCTGTCTGTGTAGAAGGGTAGACAAGTGGATGAGAAGTTCCTGAACTATTCTTGGCCCTTTTACCACTAAGTGAAAGTAACTTGCTGCCCCAAAGAAAGATGTCTCATCATTCGACAGGACTTTCTAGTtgaacttcatgaaagcaagagatcctgtttttcttgctcaccactgtatcttgagacctgttgtagtgcctgCAATACTTATTTAATAAGTTATTTTTAAGTATCAGTTTTGTGAGCTTTAACTCTATGAGGTCTTTGTTGTTTGACTGTATTTTAACTCTGGCCATGACAGCAAGACAAAGTTCCATTTTTATTGAGCTTAAAAAGAATCAAggccaggtgaagtggcttacgcctgtgatcccaacactttgtgaggctgcagcaggaggatctcttgagcccaggagtttgagaccgttctaggcaatgtagtgaggtccagactccacaaaataatttttttttaaattgcacgcctgtagtctcagctatcaggaggctgagatgggaggatgacttgagcccaggaaattgaagctgcagtgaattgtgattgcaccactgcactccagcctgggtgacagatcaagaccttgcctaaacaaaacaaaacaaacaaaaCCCCAAAAAACAAATTGAAAATGTTGATTCTTTTTACTACAAACATTATGGCAGCACTAAAAACTTCGTGGGAGTGTACTGTGGAAAATAGTGTACTTAATTAATTCTCATTGTAATCAGGCTACCAAGAGCCTTGTGTTGCTTTAAGAGTTATAACTgccaggcacagtggctcatgcctataatcccagcaccttgagaggccgaggcaggtggatcacctgagatcgggagtttgagaccagccgggccaatatggtgaaacaagctgtgtctctactaaatacaaaaaattagccgggcgtggtggcacatgcctgtaatcccagctgcttgggagactgagacaggagaattgcttgaacctggaaggcggaggttgcagtgagctgagattgcaacattgtactccagcctgggcaacaagagggaaactccatctcaaaaaaaaaaaaaaaGTTGTAACTGAggctgggcatggtggctcatacctgtaatcccagcactttgaaaagccgaggcaggtagatcacttgagctcagaagttcgagactagcctgggcaacatgacaaaaccccatctctacaaaaaatacgaaaaattagctgggcgtggtggcatgcacctgtagtcctagctacctgggaggctgaggtgggaagattacttgaagctgcagtgagccatggttgtgccactgccctccagtctgggcaacaaagtgagaccctgtctcaaaaaaacaaaaaaaaaTTATAACTGATGTAAACTGGCAGTTTAggctgggtgtggtggctcaagcctgtaatcctagcactttgggaggccaaggcaggtggatcacctgagttcaggagttcgagaccagcgtggccaacatggtgaaaccttgtctctattaaaaataccaaaattagcaagatgtggtggtgggtgcctataattccagctactcaggaggctgaggcaggaggatcgctggagccagggaggcagaggttacagtaagcaaagatcactccacttcactccagcctgggcaaaagagtgagacatatcaaaaaataaacaaataaataaataaaTAAGTGGCAGTTCATCATTTAACTCCAAAGACTTTGCGTACATTTCTACTGAAAACAATCTGAGCTGATTAGAACCCTGCCATTTTATAGCCTTTAGCTCGATCTCCGACCGTTCATTTAAAAAAATTCTACTTCAggccgggcatggtggctcaagcctgtaatcccatcactgtaggaggccaaagtgggcagatcacttaaggtcaggagtttgagaccagcctggccaccatggtgaaaccccatctctactaaaaatacaaaaattagccgggcttggtggtgagcacctgtaatcccaccctgccgagtggcaggctgaggcaggagaatcgcttgagcccaagagccggaggttgcagtgagccaagcttgcaccattgcactccagcctaggcaacagagtgtgactccatctcaagaaaaaaaaaaTTCTATTTCATTTTACAATATGCAGATATATGTCCATACACATGCATAATATAAATGTATACCATATTTGTGAGAATATGCATATATGTACACATTAGATACACAATACAAGCACAATACATATGTCTTTTGCCCAAGATACAGCATTTTGTAAAGGAGACAGGAATTTAGTAATATATGTTCCAGAAACAGTACACAAGAGAATTCGCCGAGATGAGAAAGTTGTCACTAGGAATGGGGAGTGGTAAGATGTAGAAGGTATAATTGTTCTTAAAGTTCTACTGCCAACTCTTTCCAATTAATTACCCACTCTGCCATGCTTTATGGACAGGAGGTTGTCGGACACTGTCAATTAATAAATATTTGAGCATGATACACTGCTTGGAGCTCCTCTAATATAGGAGAGTGATATCCTAGTGCATGTTACAGAGGGAGTGTCCACACAGTTCCTATTGTCATTTGATGAGTTACTTTTCAGGGGCCTTGTACCTGAGCAAGTTGTCCTCTTTTTGATGGATTTCAGATTGAGTTACCTGCATTGTCTTGAGATTGCAGCGTGTTTCCTCCACTGTACGGCGTAGTCAGCAGATCTATTAGTTAAACTCCAGTGGGCCCTCAGTCACTAAATCTATCCTCTGTGTTGAAGGCTTTCTGCATTTGCCTTTCAATAAAGGTTTAGAATAAC 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