| Gene Name | GPS2 |
|
| Specie | Homo sapiens | |
| Full Name | G protein pathway suppressor 2 | |
| Also known as | AMF-1 | |
| Coordinate | chr17:7312661-7315360 | |
| Strand | - | |
| Gene summary | This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| GPS2P2 | chr3:186773195-186773459 | + |
Intergenic |
ENSG00000230951 | UCSC |
| GPS2P1 | chr9:2875386-2876515 | - |
Intergenic |
ENSG00000236496 | UCSC |
| >NM_004489.5 |
| GGAGCCGCTGAGAAAGCGCAGAGAAGGCGGGCCCCGTCTGAGGTCTGGCAGTCAGAGACAGCCGGGCGCCCACGGCCCGAGCGCCCACGGCAGCACCATGCCCGCACTCCTGGAGCGCCCCAAGCTTTCCAACGCCATGGCCAGGGCGCTGCACCGGCACATTATGATggagcgggagcgcaagcggcaggaggaagaagaggtggataagatgatggaacagaagatgaaggaagaacaggagagaaggaagaaaaaggagatggaagagagaaTGTCATTAGAGGAGACCAAGGAACAAATTCTGAAGTTGGAGGAGAAGCTTTTGGCTCTACAGGAAGAGAAGCACCAGCTTTTCCTGCAGCTCAAGAAAGTTTTACATGAGGAAGAAAAACGGAGGCGAAAGGAACAGAGTGACCTGACCACCCTAACATCAGCTGCATACCAGCAGAGCCTGACTGTTCACACAGGAACTCATCTCCTCAGCATGCAGGGGAGCCCTGGAGGACACAATCGCCCAGGCACCCTCATGGCAGCTGACAGAGCCAAACAAATGTTTGGACCCCAAGTGCTTACGACCCGGCACTACGTGGGCTCAGCAGCTGCTTTTGCAGGGACACCAGAGCATGGACAATTCCAAGGCAGTCCTGGTGGTGCCTATGGGACTGCTCAGCCCCCACCTCACTATGGGCCCACACAGCCAGCTTATAGTCCTAGTCAGCAGCTCAGAGCTCCTTCGGCATTCCCTGCAGTGCAGTACCTATCTCAGCCACAGCCACAGCCCTATGCTGTGCATGGCCACTTTCAGCCCACTCAGACAGGTTTCCTCCAGCCTGGTGGTGCCCTGTCCTTGCAAAAGCAGATGGAACATGCTAACCAGCAGACTGGCTTCTCCGACTCATCCTCTCTGCGCCCCATGCACCCCCAGGCTCTGCATCCAGCCCCTGGACTCCTTGCTTCCCCCCAGCTCCCTGTGCAGATGCAGCCAGCAGGAAAGTCGGGCTTTGCAGCTACCAGCCAACCTGGCCCTCGGCTCCCCTTCATCCAACACAGCCAGAACCCGCGATTCTACCACAAGTGACCATCAGATTATATCTTCAACACCACACCCCCCACCCCATCGTGGGTGAGGGTATCCCCTGTGTGTCCCAGGCCAATAAAATCTACCTGCCACTG |