Summary

Gene Name	MRPS18B
Specie	Homo sapiens
Full Name	mitochondrial ribosomal protein S18B
Also known as	C6orf14|HSPC183|HumanS18a|MRP-S18-2|MRPS18-2|PTD017|S18amt
Coordinate	chr6:30617320-30626393
Strand	+
Gene summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Jul 2008]

Retrocopy(s) from MRPS18B

Retroname	Coord	Strand	Genomic Region	ENSG
MRPS18BP2	chr2:139668547-139669331	+	Intergenic	ENSG00000235232	UCSC

Expression

Transcript Sequences

>NM_014046.4_7

AATTCCTGTCCTGGGCGTACGTCAAGATGGCGGCGTCTGTATTAAACACCGTGCTGAGGCGGCTTCCTATGCTATCTCTCTTCCGAGGTTCTCACAGAGTTCAGGTTCCCCTCCAGACTCTTTGCACCAAAGCTCCCTCTGAGGAAGATTCTTTGTCCTCAGTTCCCATTTCTCCTTATAAGGATGAGCCCTGGAAATATCTGGAATCAGAAGAATACCAGGAGCGATATGGTTCTCGCCCCGTCTGGGCTGACTACCGCCGCAACCACAAGGGTGGTGTACCCCCACAGCGGACTCGGAAGACATGTATTCGTCGGAATAAAGTTGTTGGGAATCCCTGCCCCATCTGTCGAGATCACAAGTTGCATGTTGACTTTAGGAACGTGAAGCTCTTGGAGCAATTTGTCTGCGCCCACACGGGTATCATCTTCTATGCTCCATACACAGGAGTCTGTGTGAAGCAGCACAAGCGGTTGACCCAGGCCATCCAGAAAGCCAGGGATCATGGTCTCCTCATTTACCACATCCCCCAGGTTGAACCACGGGACCTTGACTTCAGTACCTCTCATGGGGCTGTGAGTGCTACTCCGCCAGCCCCCACCCTGGTCTCAGGTGACCCCTGGTACCCATGGTACAACTGGAAACAGCCACCGGAGAGAGAACTGTCTCGCCTTCGCCGGCTTTACCAGGGTCATCTCCAAGAAGAGAGTGGCCCCCCACCTGAGTCAATGCCCAAGATGCCCCCTAGAACACCAGCGGAAGCCTCCTCCACTGGGCAGACAGGCCCTCAGAGTGCTCTGTAGGAGCTGTAGACTGGGAAGAGAggccaggcgtggtggctcactcctgtaatcccagcactttgggaagccaaggtgggctgatcacttgatcccaggagtttgagaccagcctgggcaccatggtgaaacctcgtctttaccaaaaaatacaaaaattagctgggtgtggtggtgcacacctgtagtctcaactattggggaggctaaggtaggatcacttgatcccaggaggcggaggttgcagtgagttgcagtcacacccctgcactccagcctgggtgacagctagaccctgtctcaaaaaaaaaaaaaaaGACTGGGAAGAGAGCTAGAGGGACTAGGAGATAATGTGTATGTAGGTTTATGTGATGGGATATCACCCTGAAGAGTTGTGTCTTTTGTGGCCAGTGACAAATCCAGGAAATGAATGTTGCTGATAGGGATAAATCTTGAGGCTGAGGGCGGGTGGTACAGATGTGTATGGGAAACCCCAACCCCTATATATTGTAAATAGATGGGCTGGGCTAAACATTGTTGCCGTTTCATACTTCTACCAACTCAGCTTTTACACAATAAAGCTCTACTGTCTCTGGTT