Summary

Gene Name	MAX
Specie	Homo sapiens
Full Name	MYC associated factor X
Also known as	bHLHd4
Coordinate	chr14:65006101-65102541
Strand	-
Gene summary	The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Retrocopy(s) from MAX

Retroname	Coord	Strand	Genomic Region	ENSG
MAXP1	chr7:135650940-135651454	+	Intergenic	ENSG00000271414	UCSC

Expression

Transcript Sequences

>NM_002382.5

AGTGAGGAGGTGGTTCTTGCCCgtgttgtgtgtgtgtgtgagtgagagagcgagtgagtgagtgagtgagtgTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCcccctccccttcaccccttcccctccccgccGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGTCCGTGCACTGGAGAAGGCGAGGTCAAGTGCCCAACTGCAGACCAACTACCCCTCCTCAGACAACAGCCTCTACACCAACGCCAAGGGCAGCACCATCTCTGCCTTCGATGGGGGCTCGGACTCCAGCTCGGAGTCTGAGCCTGAAGAGCCCCAAAGCAGGAAGAAGCTCCGGATGGAGGCCAGCTAAGCCACTCGGGGCAGGCCAGCAATAAAAACTGTCTGTCTCCATCGTCTCATCCTCCTTTCAGTTCGTTGGTAGAGCCCTCAGAACCATTTAAGAGACTCtttatttttctctttctcccttttttttttaaatttttatttttaCGTAGAAGCTCTTGGACAACAGCTCTCGTTCTCCTTCCCCATTTCCACTGTATATTTTTTAATGTATTCCCTTCAGGGATTCCCTGTCCCCAACAGGAATTTTTAAACCAAAACACCCCAACTTGGCAGCTTTTTCTGTGGAGGACAGACGGCCGGCCGGACCTCTGAGCACATAGTGTCCTGCCCACCCTACCAGCTCCTCCAGCCCTGCCGGGCACATGCCCGGGGGACGCCTGCCCTGCCCAGGTGGCCTCCTGGCCCGCCCTCACCTCTGATAGACTTTGTGAATCTGAACTGCTCTACTTTGAGAAGATGACCGGTTTGGAGTAATCAGAATGAACCCTCCTCCTTTTTAAGGGTTTTTTTTTTTTCCTTTTTCTAAAAAGCTATGTATCGCTCCTATTGAAAGACCAGATCCTTAGAGAAGTTTGTGGTATAAAAAGGAAGTGGGGACAGATTCGCAGCACAGAGTCGCTGGCATGTTTCACTCCTGCTTCTCTCAGCCAGCTGTTTAAGCCTGCGGCGCCAGCCTCACGGAGGGCCGTGTGACACTCTCGTGGTATGTATGGGAGATGGCAGCAGTGAAGCAGCAGCCACCAGGGAGTGGCCATTTGGGGTTGGGACAGGGAGGGTGTTTTGGGTGGCATAGAGGTTTTGTATTGAGGGCCAGTGATGATGTTTTGATATTTATTTCCTGCTACTTAAATTTGAATCTGAGTGAATTGTACCTATTTCTGATGATGTCGGTCTTGCAAAGCGACAGATTCATAAAGTAATGATGAAATCTTTCTTTCTTCCCGTGTGTATTTCTAAGAAATAGAGCCAACTGATTTTGTATGTAAATACCAAGAGCAATTTACCTGGTACTAAACCCGCACCCCAGTGCGGACCCTTCCCAGCCCTCATCCCACTTCCTTTCCTACTGTCCTGGAACCTGTCTCCATTGTGTGATCCAGCCCTGGTTCTGGCTGTGGTCAGCAGATGCCAGTGAAGGGTTTTGTGTGTTTAGGCCTCATTTCTTTGTCTTTTTCCTACTCCGTTCCTGGCATTTGCTGATTTCTAGTGTATACTCTGTAGTCTCAGTTCGTGTTTGATTCCATTCCATGGAAATAAAAAGTATGTTGTACATACTGCCGAAGAATTGTCTTGCAAGTTAAGGCTTCCCCCTTTACTATAAGACTATAAATAAAAACTTATTTTATCCTT