Summary

Gene Name	ALDH7A1
Specie	Homo sapiens
Full Name	aldehyde dehydrogenase 7 family member A1
Also known as	ATQ1|EPD|PDE
Coordinate	chr5:126541841-126595219
Strand	-
Gene summary	The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]

Retrocopy(s) from ALDH7A1

Retroname	Coord	Strand	Genomic Region	ENSG
ALDH7A1P4	chr10:62741007-62741386	-	Intergenic	ENSG00000234489	UCSC
ALDH7A1P1	chr5:77290183-77291997	+	Intragenic	ENSG00000251400	UCSC
ALDH7A1P3	chr7:150541567-150542100	-	Intergenic	ENSG00000243853	UCSC

Expression

Transcript Sequences

>NM_001201377.2

ATCCCGAGTCCCGGGCTCAGTATGTGGCGCCTTCCTCGCGCGCTGTGTGTGCACGCTGCAAAGACCAGCAAGCTCTCTGGACCTTGGAGCAGGCCTGCCGCCTTCATGTCCACTCTCCTCATCAATCAGCCCCAGTATGCGTGGCTGAAAGAGCTGGGGCTCCGCGAGGAAAACGAGGGCGTGTATAATGGAAGCTGGGGAGGCCGGGGAGAGGTTATTACGACCTATTGCCCTGCTAACAACGAGCCAATAGCAAGAGTCCGACAGGCCAGTGTGGCAGACTATGAAGAAACTGTAAAGAAAGCAAGAGAAGCATGGAAAATCTGGGCAGATATTCCTGCTCCAAAACGAGGAGAAATAGTAAGACAGATTGGCGATGCCTTGCGGGAGAAGATCCAAGTACTAGGAAGCTTGGTGTCTTTGGAGATGGGGAAAATCTTAGTGGAAGGTGTGGGTGAAGTTCAGGAGTATGTGGATATCTGTGACTATGCTGTTGGTTTATCAAGGATGATTGGAGGACCTATCTTGCCTTCTGAAAGATCTGGCCATGCACTGATTGAGCAGTGGAATCCCGTAGGCCTGGTTGGAATCATCACGGCATTCAATTTCCCTGTGGCAGTGTATGGTTGGAACAACGCCATCGCCATGATCTGTGGAAATGTCTGCCTCTGGAAAGGAGCTCCAACCACTTCCCTCATTAGTGTGGCTGTCACAAAGATAATAGCCAAGGTTCTGGAGGACAACAAGCTGCCTGGTGCAATTTGTTCCTTGACTTGTGGTGGAGCAGATATTGGCACAGCAATGGCCAAAGATGAACGAGTGAACCTGCTGTCCTTCACTGGGAGCACTCAGGTGGGAAAACAGGTGGGCCTGATGGTGCAGGAGAGGTTTGGGAGAAGTCTGTTGGAACTTGGAGGAAACAATGCCATTATTGCCTTTGAAGATGCAGACCTCAGCTTAGTTGTTCCATCAGCTCTCTTCGCTGCTGTGGGAACAGCTGGCCAGAGGTGTACCACTGCGAGGCGACTGTTTATACATGAAAGCATCCATGATGAGGTTGTAAACAGACTTAAAAAGGCCTATGCACAGATCCGAGTTGGGAACCCATGGGACCCTAATGTTCTCTATGGGCCACTCCACACCAAGCAGGCAGTGAGCATGTTTCTTGGAGCAGTGGAAGAAGCAAAGAAAGAAGGTGGCACAGTGGTCTATGGGGGCAAGGTTATGGATCGCCCTGGAAATTATGTAGAACCGACAATTGTGACAGGTCTTGGCCACGATGCGTCCATTGCACACACAGAGACTTTTGCTCCGATTCTCTATGTCTTTAAATTCAAGAATGAAGAAGAGGTCTTTGCATGGAATAATGAAGTAAAACAGGGACTTTCAAGTAGCATCTTTACCAAAGATCTGGGCAGAATCTTTCGCTGGCTTGGACCTAAAGGATCAGACTGTGGCATTGTAAATGTCAACATTCCAACAAGTGGGGCTGAGATTGGAGGTGCCTTTGGAGGAGAAAAGCACACTGGTGGTGGCAGGGAGTCTGGCAGTGATGCCTGGAAACAGTACATGAGAAGGTCTACTTGTACTATCAACTACAGTAAAGACCTTCCTCTGGCCCAAGGAATCAAGTTTCAGTAAAGGTGTTTTAGATGAACATCCCTTAATTTGAGGTGTTCCAGCAGCTGTTTTTGGAGAAGACAAAGAAAATTAAAGTTTTCCCTGAATAAATGCATTATTATGACTGTGACAGTGACTAATCCCCCTATGACCCCAAAGCCCTGATTAAATCAAGAGATTCCTTTTTTAAAAATCAAAATAAAATTGTTACAACATAGCCATAGTTACTAAAAGATGAGTTAGGTGGATTTTTATTATGTCAACTAGTTGTACATGGCTTTTTAAAAGTTAATGATTATTTTGTAATTAGAAAAAAATAGTACGTACCAGGGTAGGAATTTGGGAAAATACAGAACCGAGGAGAAAACAGAAGTCTTTGCAGTAGATACAGGGTGTCTCCTGACCAAGTGAAGGATTCAGGGGCGGGGGGTGAATATTGCTTGACATTACCCACCTATGGCATGTGTTGGATGTCGTGTGATTGAAAGGGGGATGCATTCCCCTGTATGCTTGGACCACAGTTCAGTATTCATGTGGAATAACTTGCAGTGCTTAAAATGACAACAGGCATTCATCACAGTTATGGCTCTTGCTTATGAAGGCTGTGTCAACTTGGAAGAGATTTCTGGGGTAGACAGATTTTGTTCCTGTGCTGGAGTCTGCCACCTGCTGGAGGACTCTGAGGCCAAAATTGCCCGTGCAGAGTTGTATAGAAAATGCGTCTGGAggctgggcaaggtggcttacgcctataatcccagcactttgagaggccgaggcgggtggatcagtagaggctaggagtttgagaccagcctggccgatatcgtgaaaccccgtctttaccaaaaaatacaaaaattagcccagtgtggtggcaggcacctgtaatcccagctattagggaggctgaggcaggagaattgtgtgaacccaggaggcagaggttgcagtgagcctagattgtgccactgcctgggcaacagtgagatcctgtctacaaaaaaaaaaaaaaaaaaaaGTGCATCTGGATTTTTTTATACAACCTTAGACCACCTTCTTTAGCTTTAGGCGTCTGCGGTTGCCCTTGGATCTGTTCTCAATCCTCAGTGTGTGTGGCAGCATGTGGTCATAGAGAGCTGGGCAAAGTTCACTTTCTCTTTGCTGACAGTCTCACCTTTTCTCACTGGGAAGCTGCACAGGAGCCTTTGGGCTGGTTCAGCCCAGAGGCCCCTGTTCTCCTGCCTTCCTGGCATTCTCTGCTCCCCTTCTGCATGGCACCCCTCTACTCCTGCCAGGTTAGAATGGAGCAGAGGCCTTTGaacaagatgacatttgtagacaacctgatccatcaggatgtggagagatctggacaaatggcaaataatttggggttgaattatggcccagagaagtaagcaaatgaaaaactaaacaattataaatgtatctgggaagcaaaggtattcataatatgtcccatggccagctgcgagcagtatttaactagacatgctgttgtcaatattgaacatgaatcaagccaaatactgatatagctattgagagaaGGTTGGCAGGAAGAAATCATGGGTGAGGGTATGTGGGAGTGATAATCTTAGCTATAGATTTTAGGTAAAACTGATTCTGAAAGCTTTCTTTGAAACAAATTTATAATTTTTCTTCTACATGTTTCTAGCACAAGGACTCAATTTTTTTTGGTTATAATGTTCATTAAAACATATGCCTTCAATTTGTTCCTCTTTGTTCTTTTTTGCTGATTTAGCAGATATAAATCACTTGTTAGTATTTTTAACTATCCAAGTTAAAATGTACATTTGTAAGTGTTATTACTGGTCTTATATTTGAAGGTGCAAGGGGTCTTGTGCTGCTCATTACTGGTTATCTTGAGCATTTCATAACTGCTGCCTCCTCCTAAATCCTGTGTTCCAACCGCTACTGCTGGCAATGCCCAGCCTCCATTGTGGATGCGGGGAATTGTGTTCAGCATGCTTGCTTCTGCCACGGCACTAAAGCCTAACTTGCTTAGGATCTTGCTGTACTTGGAGAGAGCATCCATTCGCTGAGCCTAGCAGCCAGGCTCTTGTGACTCCCTGGGAAGTGGGTGAAGACCTGGCTCCTGGCTGCAGCAGTGAGGAGGCAGGCCCTCCAGGTGAAGACTTCTCACAATGGAGGGAAGGCAGTTTTCTCAAAGGAAATTGAGTGCTATTATGTACTCTGCTTCCTACTTTCTCTTTCAGGGTGGGAATCTGTTAAGCCTCCTCTCTCTCTTGCTCTGCAACCACAGAACACttctttttttttggtgtctcagttttgcccacactggagtgcagtggtgcaatagtggctcactgcagcctccaactcctgggctcaatctatccttccacctcatgctccccagtagctgggactacaggtgcatgccactgtgcccagctgattattatttttttttgtaaagattgggtcatactacattgctcatgctcgtcttgaacttgtggcctcaagcgatcctcctgcctcagcctcttgagttgttgggattacaggagtgtgccaccatgcccagcTCTGTGGAAAATTCTCTGTGGCATTCTGTCTCCTGAAAATGCTGAAGGGACCAAGAGGGCTCTGTGTCCTTCCTCTTCTCTTCCCTGGCACTTTCAGACCATTTTCTTGTTGCCTTCATTCTAACAAAGGTTGCAGATTGGAAAGCTGATTTGGAATGCTTTTTAAGTGTTTTCAGTTTCAATATTTTTATGAAATTCCTATGGTCTCCAACAAACttttttttttttttttttttCTACACCTGGAGCTTATCCTGCAGAAGCTTCCTGCCAATGATTGTTTTGGAGGAAATTAAAAGAAAACCAAACGAAACCTCTCCTATCCAAGGGGAAGAACTTTATCCCCATATTGATTGAATATAGGATTCTAGATTTAAAATGTTGTAGGCAGTTAGAGTTTGCTCTTTTTTTTTTTCTATTGGAAAGGTCCACAAATGTTTTATTGACATTTTTGTCTTTAATCCATTTGGATTTGGGGTACATGTTACGATTTGTCTACGTTAATTTCCCTTTTAAAAATAAAAATAATTCCTCAACTCCAA