Retrocopy Name | ALDH7A1P3 |
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Species | Homo sapiens | |
Coordinates (hg38) | chr7:150541567-150542100 UCSC | |
Coordinates (T2T) | chr7:151719931-151720464 UCSC | |
Coordinates (hg19) | chr7:150238655-150239188 UCSC | |
Strand | - | |
Parental Sequence | NM_001201377.2 | |
Parental seq. overlap | 470 bp | |
Parental seq. overlap (%) | 9.9% | |
Genomic Region |
Intergenic |
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Retrocopy Summary | ALDH7A1P3, located on chr7:150541567-150542100, is a retrocopy of the parental gene ALDH7A1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
Gene Name | ALDH7A1 |
Full Name | aldehyde dehydrogenase 7 family member A1 |
Also known as | ATQ1|EPD|PDE |
Coordinate | chr5:126541841-126595219 |
Strand | - |
Gene summary | The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011] |
Species | Scientific Name | Retrocopy | |
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Chimpanzee | Pan troglodytes | ALDH7A1P2 |
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Bonobo | Pan paniscus | ALDH7A1P2 |
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Gorilla | Gorilla gorilla | ALDH7A1P1 |
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Orangutan | Pongo abelii | ALDH7A1P2 |
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Green monkey | Chlorocebus sabaeus | ALDH7A1P3 |
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Gibbon | Nomascus leucogenys | Without Homology |
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Crab-eating macaque | Macaca fascicularis | Without Homology |
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Rhesus | Macaca mulatta | Without Homology |
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Baboon | Papio anubis | Without Homology |
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Golden snub-nosed monkey | Rhinopithecus roxellana | Without Homology |
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Marmoset | Callithrix jacchus | Without Homology |
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Mouse lemur | Microcebus murinus | Without Homology |
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Mouse | Mus musculus | Without Homology |
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Rat | Rattus norvegicus | Without Homology |
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Chinese hamster | Cricetulus griseus | Without Homology |
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Rabbit | Oryctolagus cuniculus | Without Homology |
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Pig | Sus scrofa | Without Homology |
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Cow | Bos taurus | Without Homology |
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Sheep | Ovis aries | Without Homology |
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Dolphin | Tursiops truncatus | Without Homology |
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Horse | Equus caballus | Without Homology |
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Dog | Canis familiaris | Without Homology |
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Panda | Ailuropoda melanoleuca | Without Homology |
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Cat | Felis catus | Without Homology |
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Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
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Velvety free-tailed bat | Molossus molossus | Without Homology |
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Greater mouse-eared bat | Myotis myotis | Without Homology |
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Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
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Greater horseshoe bat | Rhinolophus ferrumequinum | Without Homology |
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Egyptian rousette | Rousettus aegyptiacus | Without Homology |
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Sloth | Choloepus didactylus | Without Homology |
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Tasmanian Devil | Sarcophilus harrisii | Without Homology |
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Opossum | Monodelphis domestica | Without Homology |
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Platypus | Ornithorhynchus anatinus | Without Homology |
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Chicken | Gallus gallus | Without Homology |
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Turkey | Meleagris gallopavo | Without Homology |
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Zebra Finch | Taeniopygia guttata | Without Homology |
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Budgerigar | Melopsittacus undulatus | Without Homology |
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Painted Turtle | Chrysemys picta | Without Homology |
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Lizard | Anolis Carolinensis | Without Homology |
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Frog | Xenopus tropicalis | Without Homology |
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Zebrafish | Danio rerio | Without Homology |
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Drosophila | Drosophila melanogaster | Without Homology |
>ALDH7A1P3 |
ACACAGAGACTTTTGCTCCAATTCTCTATGTTTTTAAATTTAAGAATGAAGAAGAGCTCTTTGTGTGAAATAATGAAGTAAAACAGGGTATTTCAAGTAGCATCTTTACCAAAGATTTGGGCAGAATCTTCCACTGGCTTGGACCTAAAAGATCTAACTGTGGCATTGTAAATGTCAATATTCCAATGAGCGGAGCTGAGATTGCAGGTGCATTTGGAGGAGAAAAGCACATTTGTGGTGGCAGGGCATCTGGTGATGACTCCTGGAAATAGTGCATGAGAAGGTTTACTTGTATCATCAACTATGGTAAGGATCTTCCTCTGGTGAAAGGAATCAAGTTTCAGTAAAGTTTTATGGACGAACATTGCTTAATTTTAGGTGTTCCTGCAGCTGTTTCTGAAGAAGAAAAAAAAAATTAAAATTTTCCCTGAATAAATGCATCATTATGACTATGACAGTGACTAATGTCTTATGACCCCAAAGCCCTGATTAAATCAACAGACTCATTTTTTAAAAAATCAAAACAAAATTGTC |
>NM_001201377.2 |
ATCCCGAGTCCCGGGCTCAGTATGTGGCGCCTTCCTCGCGCGCTGTGTGTGCACGCTGCAAAGACCAGCAAGCTCTCTGGACCTTGGAGCAGGCCTGCCGCCTTCATGTCCACTCTCCTCATCAATCAGCCCCAGTATGCGTGGCTGAAAGAGCTGGGGCTCCGCGAGGAAAACGAGGGCGTGTATAATGGAAGCTGGGGAGGCCGGGGAGAGGTTATTACGACCTATTGCCCTGCTAACAACGAGCCAATAGCAAGAGTCCGACAGGCCAGTGTGGCAGACTATGAAGAAACTGTAAAGAAAGCAAGAGAAGCATGGAAAATCTGGGCAGATATTCCTGCTCCAAAACGAGGAGAAATAGTAAGACAGATTGGCGATGCCTTGCGGGAGAAGATCCAAGTACTAGGAAGCTTGGTGTCTTTGGAGATGGGGAAAATCTTAGTGGAAGGTGTGGGTGAAGTTCAGGAGTATGTGGATATCTGTGACTATGCTGTTGGTTTATCAAGGATGATTGGAGGACCTATCTTGCCTTCTGAAAGATCTGGCCATGCACTGATTGAGCAGTGGAATCCCGTAGGCCTGGTTGGAATCATCACGGCATTCAATTTCCCTGTGGCAGTGTATGGTTGGAACAACGCCATCGCCATGATCTGTGGAAATGTCTGCCTCTGGAAAGGAGCTCCAACCACTTCCCTCATTAGTGTGGCTGTCACAAAGATAATAGCCAAGGTTCTGGAGGACAACAAGCTGCCTGGTGCAATTTGTTCCTTGACTTGTGGTGGAGCAGATATTGGCACAGCAATGGCCAAAGATGAACGAGTGAACCTGCTGTCCTTCACTGGGAGCACTCAGGTGGGAAAACAGGTGGGCCTGATGGTGCAGGAGAGGTTTGGGAGAAGTCTGTTGGAACTTGGAGGAAACAATGCCATTATTGCCTTTGAAGATGCAGACCTCAGCTTAGTTGTTCCATCAGCTCTCTTCGCTGCTGTGGGAACAGCTGGCCAGAGGTGTACCACTGCGAGGCGACTGTTTATACATGAAAGCATCCATGATGAGGTTGTAAACAGACTTAAAAAGGCCTATGCACAGATCCGAGTTGGGAACCCATGGGACCCTAATGTTCTCTATGGGCCACTCCACACCAAGCAGGCAGTGAGCATGTTTCTTGGAGCAGTGGAAGAAGCAAAGAAAGAAGGTGGCACAGTGGTCTATGGGGGCAAGGTTATGGATCGCCCTGGAAATTATGTAGAACCGACAATTGTGACAGGTCTTGGCCACGATGCGTCCATTGCACACACAGAGACTTTTGCTCCGATTCTCTATGTCTTTAAATTCAAGAATGAAGAAGAGGTCTTTGCATGGAATAATGAAGTAAAACAGGGACTTTCAAGTAGCATCTTTACCAAAGATCTGGGCAGAATCTTTCGCTGGCTTGGACCTAAAGGATCAGACTGTGGCATTGTAAATGTCAACATTCCAACAAGTGGGGCTGAGATTGGAGGTGCCTTTGGAGGAGAAAAGCACACTGGTGGTGGCAGGGAGTCTGGCAGTGATGCCTGGAAACAGTACATGAGAAGGTCTACTTGTACTATCAACTACAGTAAAGACCTTCCTCTGGCCCAAGGAATCAAGTTTCAGTAAAGGTGTTTTAGATGAACATCCCTTAATTTGAGGTGTTCCAGCAGCTGTTTTTGGAGAAGACAAAGAAAATTAAAGTTTTCCCTGAATAAATGCATTATTATGACTGTGACAGTGACTAATCCCCCTATGACCCCAAAGCCCTGATTAAATCAAGAGATTCCTTTTTTAAAAATCAAAATAAAATTGTTACAACATAGCCATAGTTACTAAAAGATGAGTTAGGTGGATTTTTATTATGTCAACTAGTTGTACATGGCTTTTTAAAAGTTAATGATTATTTTGTAATTAGAAAAAAATAGTACGTACCAGGGTAGGAATTTGGGAAAATACAGAACCGAGGAGAAAACAGAAGTCTTTGCAGTAGATACAGGGTGTCTCCTGACCAAGTGAAGGATTCAGGGGCGGGGGGTGAATATTGCTTGACATTACCCACCTATGGCATGTGTTGGATGTCGTGTGATTGAAAGGGGGATGCATTCCCCTGTATGCTTGGACCACAGTTCAGTATTCATGTGGAATAACTTGCAGTGCTTAAAATGACAACAGGCATTCATCACAGTTATGGCTCTTGCTTATGAAGGCTGTGTCAACTTGGAAGAGATTTCTGGGGTAGACAGATTTTGTTCCTGTGCTGGAGTCTGCCACCTGCTGGAGGACTCTGAGGCCAAAATTGCCCGTGCAGAGTTGTATAGAAAATGCGTCTGGAggctgggcaaggtggcttacgcctataatcccagcactttgagaggccgaggcgggtggatcagtagaggctaggagtttgagaccagcctggccgatatcgtgaaaccccgtctttaccaaaaaatacaaaaattagcccagtgtggtggcaggcacctgtaatcccagctattagggaggctgaggcaggagaattgtgtgaacccaggaggcagaggttgcagtgagcctagattgtgccactgcctgggcaacagtgagatcctgtctacaaaaaaaaaaaaaaaaaaaaGTGCATCTGGATTTTTTTATACAACCTTAGACCACCTTCTTTAGCTTTAGGCGTCTGCGGTTGCCCTTGGATCTGTTCTCAATCCTCAGTGTGTGTGGCAGCATGTGGTCATAGAGAGCTGGGCAAAGTTCACTTTCTCTTTGCTGACAGTCTCACCTTTTCTCACTGGGAAGCTGCACAGGAGCCTTTGGGCTGGTTCAGCCCAGAGGCCCCTGTTCTCCTGCCTTCCTGGCATTCTCTGCTCCCCTTCTGCATGGCACCCCTCTACTCCTGCCAGGTTAGAATGGAGCAGAGGCCTTTGaacaagatgacatttgtagacaacctgatccatcaggatgtggagagatctggacaaatggcaaataatttggggttgaattatggcccagagaagtaagcaaatgaaaaactaaacaattataaatgtatctgggaagcaaaggtattcataatatgtcccatggccagctgcgagcagtatttaactagacatgctgttgtcaatattgaacatgaatcaagccaaatactgatatagctattgagagaaGGTTGGCAGGAAGAAATCATGGGTGAGGGTATGTGGGAGTGATAATCTTAGCTATAGATTTTAGGTAAAACTGATTCTGAAAGCTTTCTTTGAAACAAATTTATAATTTTTCTTCTACATGTTTCTAGCACAAGGACTCAATTTTTTTTGGTTATAATGTTCATTAAAACATATGCCTTCAATTTGTTCCTCTTTGTTCTTTTTTGCTGATTTAGCAGATATAAATCACTTGTTAGTATTTTTAACTATCCAAGTTAAAATGTACATTTGTAAGTGTTATTACTGGTCTTATATTTGAAGGTGCAAGGGGTCTTGTGCTGCTCATTACTGGTTATCTTGAGCATTTCATAACTGCTGCCTCCTCCTAAATCCTGTGTTCCAACCGCTACTGCTGGCAATGCCCAGCCTCCATTGTGGATGCGGGGAATTGTGTTCAGCATGCTTGCTTCTGCCACGGCACTAAAGCCTAACTTGCTTAGGATCTTGCTGTACTTGGAGAGAGCATCCATTCGCTGAGCCTAGCAGCCAGGCTCTTGTGACTCCCTGGGAAGTGGGTGAAGACCTGGCTCCTGGCTGCAGCAGTGAGGAGGCAGGCCCTCCAGGTGAAGACTTCTCACAATGGAGGGAAGGCAGTTTTCTCAAAGGAAATTGAGTGCTATTATGTACTCTGCTTCCTACTTTCTCTTTCAGGGTGGGAATCTGTTAAGCCTCCTCTCTCTCTTGCTCTGCAACCACAGAACACttctttttttttggtgtctcagttttgcccacactggagtgcagtggtgcaatagtggctcactgcagcctccaactcctgggctcaatctatccttccacctcatgctccccagtagctgggactacaggtgcatgccactgtgcccagctgattattatttttttttgtaaagattgggtcatactacattgctcatgctcgtcttgaacttgtggcctcaagcgatcctcctgcctcagcctcttgagttgttgggattacaggagtgtgccaccatgcccagcTCTGTGGAAAATTCTCTGTGGCATTCTGTCTCCTGAAAATGCTGAAGGGACCAAGAGGGCTCTGTGTCCTTCCTCTTCTCTTCCCTGGCACTTTCAGACCATTTTCTTGTTGCCTTCATTCTAACAAAGGTTGCAGATTGGAAAGCTGATTTGGAATGCTTTTTAAGTGTTTTCAGTTTCAATATTTTTATGAAATTCCTATGGTCTCCAACAAACttttttttttttttttttttCTACACCTGGAGCTTATCCTGCAGAAGCTTCCTGCCAATGATTGTTTTGGAGGAAATTAAAAGAAAACCAAACGAAACCTCTCCTATCCAAGGGGAAGAACTTTATCCCCATATTGATTGAATATAGGATTCTAGATTTAAAATGTTGTAGGCAGTTAGAGTTTGCTCTTTTTTTTTTTCTATTGGAAAGGTCCACAAATGTTTTATTGACATTTTTGTCTTTAATCCATTTGGATTTGGGGTACATGTTACGATTTGTCTACGTTAATTTCCCTTTTAAAAATAAAAATAATTCCTCAACTCCAA |
PMID - Link | Title |
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