Summary

Gene Name	MRPS16
Specie	Homo sapiens
Full Name	mitochondrial ribosomal protein S16
Also known as	CGI-132|COXPD2|MRP-S16|RPMS16|S16mt
Coordinate	chr10:73248849-73252644
Strand	-
Gene summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described. [provided by RefSeq, Jul 2008]

Retrocopy(s) from MRPS16

Retroname	Coord	Strand	Genomic Region	ENSG
MRPS16P2	chr20:59113077-59114865	+	Intergenic	ENSG00000232925	UCSC
MRPS16P3	chr22:35703835-35704519	+	Intergenic	ENSG00000226336	UCSC
MRPS16P1	chr8:91917415-91918639	+	Intergenic	ENSG00000229182	UCSC

Expression

Transcript Sequences

>NM_016065.4

ATCCGCTTCCGGAGTCGAGGTTTTCGGGCTTGTACCGCTTGGCGGTGCGGCCTGGTGTCGGCTTGCAGGTTCTTTCTGTGTTTGTTCTCTGCCCTGCCAAGGCCGTAGAGCTGGTGCGTGCGGGTAGCGGGGCTCTCCGAGGAGCCGCACGCCGGCGGCACCATGGTCCACCTCACTACTCTCCTCTGCAAGGCCTACCGTGGGGGCCACTTAACCATCCGCCTTGCCCTGGGTGGCTGCACCAATCGGCCGTTCTACCGCATTGTGGCTGCTCACAACAAGTGTCCCAGGGATGGCCGTTTCGTAGAGCAGCTGGGCTCCTATGATCCATTGCCCAACAGTCATGGAGAAAAACTCGTTGCCCTCAACCTAGACAGGATCCGTCATTGGATTGGCTGCGGGGCCCACCTCTCTAAGCCTATGGAAAAGCTTCTGGGTCTTGCTGGCTTTTTCCCTCTGCATCCTATGATGATCACAAATGCTGAGAGACTGCGAAGGAAACGGGCACGTGAAGTCCTGTTAGCTTCTCAGAAAACAGATGCAGAAGCTACAGATACAGAGGCTACAGAAACATAAATGAGCTGACTTTAGTGAGCATAGCAGTGGGAACAAGGTCAAGGTCCTTTTGAAACACTGCAGCGATCTTAATTTTGTTAGATTTGGAGTTCAATAAATGGAGTATCCTGAGTTGCCCTTGCTCTTCTGGCCTGGCCTGCACAGGGCCCAGGGAGAGATTTGTTCTTGTGTGACTTAGAGCTGGGTGTGGGTACTAATTAGCTTTTTTCGACTTTGTCTTGGGATAGACAGTGGCTATGGGAGGATTGGACTTTTGAGTTGGGCTCTGGGTCTCTTGGACAACTTTACAATTTACTGGCTTCCAAGACTTCCTGCTTCAAAACCCCCAGCCAGACTATTCATGGCCCATTCAGATCTTCATGTTCATCCCACAAGTGCAAGAACAGTTAACCTTTCTTAATTGATTTTTGTAATTGGAGGTTTATATTGTCTTGCCTAATGCATAttctctttttttttttttttttgagacggagtcttgttctgttgccaggctggagtgcggtggtgcaatctcagctcactgcaatctccacctcctgggttcaagaggttctcctgcctcagcctcctgagtagccggggagctacaagcatgcaccaccacacccagctaattttttttttttttttgagaggagtctcgctctgtcgcccaggcttgagtgcagtggcgcgatctcggctcactgcaagctctgtctcctgggttcatgccattctcctgcttcagcctcccgagtagtcccaggagtagctgggactacaggtgcccaccaccacacccagctaatttttttgtatttttagtagagatggggtttcaccatgttatccaggatggttttgatctcctgacctcgtgatccgcccgccttggcctcccaaaagtgctgggattataggcgtgagccaccgcccgggcaaatttttgtatttttagtagagatggggtttcaccgtgttggccaggatggtctcaatctgaccttgtgatctgcccacctcggcctcccaaagtgctaggattactggcgtgagccaccactcctagccTTAATGCATATTCTTAAATATACAAAGGTAGATTTGTTATGAAAATTGCTTTGGGGCTCTAATAACCTACCTTTTAAGAATGAGAAACTGCTGGGCTTAAGGGAGTTCAGTATGAATCAAGATTGAACCATTCAAATGTGGCTGTGATTTCTGCATATATCATAGATGGGATCCTTCTGAGAATACTGGAATAGGGAATTAGGACACCAAGCCAATTCAGCTGTGAACCTTATTCTTGTACTTTTCTTTCTTGCTGGTAATTTTATGGAGCAGGTTAAGAAGGCTGCTCTGTGTTAGGATAAACTGTATACCAATAATGTTGACAACCTGTAATGAGTGTTGCATTTTACTTCTTGTATCTTTTCCTTCCTACCTTGATGCCAGTAATCTATAAGGGATCTTTATAGTTTGAATGTATTTGAATAACTTCAGTATACTTTAGTTCTACTTTTTTATTTGACTCACAACCATTCTTAGGTCTCAAGTATTCCCATGTGTTTTAAAAGCCTGAAGTCAGTGAGATGAAATTCAACATCAAGAATTTGAAGTAACTTGTAAGGAAAAATAATATAAAGATACCATTggggcagtggctcacacctgtaatctcagcactttgggaggctgaggtggaaggatcacttgaagccagagtttgagaccagcctgtgcaacacagcaagaccccgtctctacaaaaacttaaaaaattagctggctgtggtgttgctcacccatagttccagctactcgggaagctgaggcagtaagatcacttgagcccaggaggccgatgctgcagtgaactgtgattgttccactacagtccagcctgggtgacagagAAAAGAAAAAGAAAACATTACATAATTTGGCTAGAGCATAATAATTTGATTTTCTGGTTTTTGAAAATTTGAGTTGCAATAAAAGGATATTTCAGTGTGCGA