| Gene Name | BRWD1 |
|
| Specie | Homo sapiens | |
| Full Name | bromodomain and WD repeat domain containing 1 | |
| Also known as | C21orf107|DCAF19|N143|WDR9|WRD9 | |
| Coordinate | chr21:39184176-39321595 | |
| Strand | - | |
| Gene summary | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| BRWD1P1 | chr1:13555064-13557933 | + |
Intergenic |
ENSG00000215909 | UCSC |
| BRWD1P2 | chr12:89917470-89919893 | - |
Intergenic |
ENSG00000258290 | UCSC |
| BRWD1P3 | chr7:17031458-17033452 | - |
Intergenic |
ENSG00000232841 | UCSC |
| >NM_001007246.3 |
| AGGCGGCGCGCACGGTATggcggcggcggcggcggcggcggcgCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACAcgctccgctcgctcgctcgctcCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGGTACCTTAATTTGAAGAAGTGTTCTGCTTTGTATTAATAGCCTAATAATTATTATAATTGTGAAGTAATGTAAGCATTGTGGAAGAAAGGTGATAATGTAACTATAAATCATGCTGTGGACTATAAAATTCTCTGCATTTAGCATAGAACATTGAATTTTATTACATAAGTGTTTAATGGGTCCTTCTGCATTAAAAAGTTGATAAAGATATAGATGTTAAGCTAAAAAGCTTGAATTTATTCTGAGATGTTGTTTGAGGTTTTATCAATGTGAGTTCTTAATTTTCCATTTTGTAGCTCACTCATAACTTCATTGAATGTAATTGTATGTGTCTAATAAACTCTTTAAATGCTAGAGGTATTTCATTTGATATTTAGCTTCTGAAAGCCCTTTGTTATAAAGGGAAGTGATTTTCTAAATTTGGTAGCAGCTTGAAAACAAGCACCACAAATGTAAAACTGCATGGTTCTTTTTTTACTAATTTAATTTTTTTGCCAAGTTATGTGCTAGCAAAATGTTTGAAATTGCTATTCTTTTTCTGTTAGCTTGGTATATATGACTTAGACTAAGTATATGTATGTGATATAAtatatgtgtacatgtggctaaactgctaatgggcaaagattgttggttcttctgatgctgagtatacatcaagttcatcccatgattattttttattacgagctattgctgatgtgatgctactcttagctgcaccaccagtataaagcttaactgagaaagaacacccctccctcttagttccgtgccagactggtttgttagctttagttgtttcttagtgctctagccatgtcaccctgtggcactaatcaggacactgtttatattcttcctcttctgtgtccctattcactttgtaattattctattttagctggttatatggtagttaattggtagcctgttttcctttgttttctttacttgtgtcaagctccatgtcgttgttttgtgatgagcagtgatttagaactggccagacCTTAGAAGAGTCTTCAGCAAGCTGCCCTAGGGTAGGGGCGTATTCTCTGTTTGTTTTGTACTGGTACCCCAGGAGGATGCCTTGTAACTGCTCTTTGGTCATGATAGTGGTAATGAATCCATTCATGTAAAATGCAATATGTCTGTTAGTTTGGGGCACCCGAGGCTCAGTAGAGGTTTAGTATGATGCCTTCCCTTTCTTCTTTGAGTTATGAAGAAACTAATTTCTGGCACAGTGTGACTGCTTCAAACCTATGTTCTGCTGCTATCTCCTATAGAGGAGGGCAGACTTTTTTTTCTTAGTGCATTTGCTGGTAGGTCAAGGAGGGATGGACTTTGAATTAGTGTTCAGAGTCACAGATCCTACGTATGTGCTCTTCAGTAGAGGATTTTCTGTGATCCTACAATGAAGGGAAAGCTATATAATTTATTGGTACTTCCTAAAGATAGAGACTAAAGTCATGGTAGTATTGGCCAAATTAATTTTAAAACTGAACAAGTCATGAATTTTCATATAAATCAAAGAACTTTTTCCTTATAAAAGCTTCCATTTTTGAAAAGTTGGATCAGTTGTAAGACCTTTCATCTTTAGTATTGTATGATATAATTCTACATTGAAAAATAAACACTTGGCATTAAATGggacttggagtcaaaagatctggttttatggtccatcttttaccaatcatttgctgtggatctctttaaaggtcctggaacctttgagcctcagttacctcacttgtaaattggcaaaaatacctacctcacagggttgttgtgaggattcaatgagctaatgtatgttgaaagcactttgtgaattgtaaagtgctacacaaatgttagttgttgttGCTGCTGTATCTGAGATGTCTTAATTTTCTTTTTCTTCAGAAATAGTCTAATAAACCTCCAGGGCTTTTCTGTTAAAGTATACTAGTTGGTAAAATGTTGAATAAACAGTTTATTACAATATA |