Summary

Gene Name	N4BP2
Specie	Homo sapiens
Full Name	NEDD4 binding protein 2
Also known as	B3BP
Coordinate	chr4:40056223-40187039
Strand	+
Gene summary	This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Retrocopy(s) from N4BP2

Retroname	Coord	Strand	Genomic Region	ENSG
N4BP2P1	chr15:30288380-30288780	+	Intergenic	ENSG00000270955	UCSC
N4BP2P2	chr15:32249900-32250300	-	Intergenic	N/A	UCSC

Expression

Transcript Sequences

>XM_011513716.2

TTGCAGCCTGGACCCCGCGCGCGTCAGGGCTCGTCCCAGCTCTGCTTTCCTTTCTCCCCTCACCTCGCGAGGCCGACCTTGTGTTTGTTTTGTTTTTTGGGGCTCGGGAGAGTGCCGAGGGCTAGAAACAGCTGTGGTTTACCGCGCCGCTTATTTTGGCAAAAATTCCGGGCCTGTTGCAATGTTCCCCAGCGCCAAACAGCTCCCGCCTTCCCCCCAAGCAGAACCCGACACTCGAAGAAGGGCTTGCTCCTCCAGGGACCCCCTGATAAGAAAAGTGGGGACCACGGCCCGCTCTCGGGCGAGACTTGGGGGGTGGGCGACCGGAAGCAGCCGAACCGGCCGGGCAGGGCTTGCTCTCCAACGGGAGAGCGGGAGCGGGAGAGGTGGGAGCGCCCGCGGGCTCAAGTCCCCCGGGCCGCCGCGCCGAGGCGGAGCTCGGGGACGAAGCAGAGGTCGTGGCGGACAGCCGGCGGGCTTGGGGGGGGGCGGTGGGCGGCGATCCACCTGGGCGACGTGGCAGCCATTGCCGGCGCCTCGAGACCCCTCcccacccggccgcccacccgccctctcgcGGCGGGCTTCTGCGCGGCTGCTCTTCCCCGGCCGGACGGAGAGCGGCAGTGTCTCCCCGCCGGGCGCGCTCGCCGTGTCTCCCCCGCGGCCGCAGCTGCTTGCTAGCCTTGCGCGGCGCGGGAGAGCGCAGTGGCGCCGGCGGGAAAGGGCTGCGGACCTGCGGCGCCGCGTTGTGCGTTCGACGACGCGGCACCGGCTTCGACGCCCTCTGCCCGCTCCAGAAGCAGTTGAAAATGCTATGGATTGTCTATTAGAATTATCTGCCACTGATACCAAGATAGAAGAATCATCTTCACAAAGTTTCGTTGCTTCTGAGAACCAAGTAGGTGCAGCAGAAAGTAAAATAATGGAAAAACGTCCTGAAGAAGAGAGTGAAGATTCAAAAATGGATTCATTTTTGGACATGCAGCTAACTGAAGACCTGGATTCCTTAATACAGAATGCTTTTGAGAAATTGAACTCTTCTCCTGATGACCAAGTATACTCATTTTTGCCTTCACAAGATGTTAATAGTTTTAATGACTCAAGTGAGTTTATAAATCCTGATTCAAGTAATATGACTCCCATTTTTTCTACACAAAATATGAATTTGAACGGTGAAAATTTAGAGAATTCTGGTTCTACTTTAAGTTTAAACCCATTACCTTCACATTCAGTTTTGAACGAGTCCAAGTGTTTTATAAAGGATAACACATTGGCTTTGGAAAGTAACTACCCGGAAGATTCTCTTCTCAGTAGTTCTTTAAATGTAGCAAGTGACTCCATCGCAGGTTGTAGCAGTCTCAATCAAAAACAGAAAGAACTTTTAGAATCTGAGTGCGTTGAGGCTCAATTCTCTGAAGCTCCTGTAGATTTGGATGCCAGTGAACCTCAGGCTTGTTTAAACCTTCCAGGGCTTGATTTACCAGGTACAGGTGGGGATCAGAAATCTACTCGGGTCTCTGATGTGTTTCTACCTTCCGAAGGGTTCAACTTCAAGCCACACAAACATCCTGAACTGCCAACTAAGGGGAAGGATGTGAGTTACTGCCCGGTACTTGCTCCTCTCCCATTGCTGTTGCCTCCTCCGCCACCTCCACCGATGTGGAATCCAATGATTCCTGCTTTTGACCTCTTCCAAGGAAACCATGGCTTTGTAGCTCCTGTTGTAACCACAGCTGCACACTGGAGATCTGTCAACTACACATTTCCACCCTCAGTTATTTCTCACACTTCCCCAACAAAAGTATGGAGAAATAAAGATGGAACAAGTGCTTATCAAGTACAAGAAACCCCAGTTTCTCAGGTTGTAAGAAAGAAGACATCTTACGTTGGACTAGTTCTTGTTCTTCTCAGAGGTCTTCCGGGATCTGGAAAATCTTTTTTGGCAAGGACTTTGCAAGAGGATAATCCAAGTGGAGTCATTCTTAGTACTGATGATTATTTTTATATAAATGGACAGTACCAGTTTGATGTAAAGTACTTAGGAGAAGCACATGAATGGAACCAGAATCGTGCAAAAGAAGCATTTGAGAAGAAGATATCTCCTATAATTATAGATAATACAAACCTACAGGCATGGGAAATGAAACCATATGTTGCTTTGTCTCAGAAACACAAATATAAAGTCCTTTTTCGGGAACCAGACACATGGTGGAAGTTTAAACCAAAGGAACTTGCAAGGCGTAACATTCATGGGGTAAGCAAAGAAAAAATAACAAGAATGTTGGAACATTATCAACGTTTTGTTTCAGTGCCAATAATTATGAGTTCTTCGGTTCCAGAGAAAATTGAACGTATTGAGTTGTGTGCATATTCTTGTGAGGATAGAAGCACTAGCCCAAGAGACGATGAAGATATTATCTCTGAAAAAGAAGAAAATATTTTATCTTTATCTTTGAAGCATCTAGAGTTCACTGAAGAGAAGAATCTTGATGTAACCAAAGAAACAATGTTACCTGAGAATGTTGCATATCTCTCTAATGCAGATTTAAACAAAAGAAGAAAAGAAATAAGTGATATGAATCCTAGCATTCAAAGTGCTTTAATTCTGGAAACTCCACACATGTATTTTTCTGACTCTGAAAGCAAACTACAGGCAACAGACAAAAGTGAAAACGAGCAAATAGAAATGGTGGCTGTAAAAGGGTATAGTAAAACTGACACAGATAGTTCTATGGAGAGAGTATCACCTAGTACTTGCTGTAGTGAAAATAATCAAGAAGACTGTGATCTTGCAAATAGTGGACCACTTCAAAATGAAAAATCCTCACCTGGTGAAATAGTGGAAGAAAGAGCAACAGTAACGAAAAAAGCCTTTGGGAAACAAAAAAGCAAATCGACTTTGGAAAAGTTCCCAAGACATGAGCTATCAAATTTTGTTGGTGACTGGCCAGTTGATAAGACTATTGGTCAGAGGACAAAAAGGAACAGAAAAACTGAAAAAACTTCATCCGTACAAAGCGACAAAAAGTATAATTACCCTCAGTCACACAAATTAGTTAACAGTGTATCTGTGAATACAGATTGTGTCCAGCAACGAGGATCTCCACATGAAAGTGTAGAGGATGGCAGAAAGTCACAGTGTGATGATGCTTCAGAGCCACTCAATAGCTATAAATATGATGCTTATAAAAATATTGACAAAAACTCATTCAACATTATGGGTGACTGGCCTTCATCTGATTCTTTAGCTCAGAGGGAACACAGATCAAGAATGCCAAAGACTGGTTTAAGTGAGCCCAACCTAGAAATTGGAACAAATGACAAAATGAATGAAATATCCTTATCTACAGCACATGAGGCCTGTTGGGGCACAAGCTCTCAAAAACTAAAGACATTGGGTAGCTCCAATCTAGGAAGTTCTGAAATGCTGCTCAGTGAAATGACCTGTGAGAGTCAGACTTGTCTAAGTAAAAAGAGTCATGGGCAACACACATCGTTGCCTCTTACTTTTACCAATAGTGCACCAACTGTTTCTGGAGTAGTAGAACCACAAACGTTAGCTGAATGTCAAGAGCAAATGCCTAAGAGAGACCCTGGAAAAGAAGTAGGCATGTGCACCCAGACTGAACCACAGGATTTTGCTCTTTTATGGAAAATAGAAAAGAATAAAATTAGCATTTCAGATTCTATCAAAGTATTAACAGGAAGATTAGATGGATTTAAGCCGAAAGTTTTCAATATTAACACAAAATCAGACGTTCAAGAAGCAATTCCATATAGAGTAATGTATGATAAAAGCACGTTTGTTGAAGAAAGTGAGCTTACCAGTGCAGATGAATCTGAAAATCTTAACATTCTTTGTAAACTGTTTGGATCCTTTTCATTAGAAGCCCTGAAAGACTTATATGAGAGGTGCAATAAAGATATTATTTGGGCCACAAGCCTTTTGTTGGATTCTGAAACTAAGTTATGTGAGGATACAGAGTTTGAGAATTTCCAAAAATCGTGTGATGGATCACAAATTGGGCCTTTTTCTCTGGGGTTGAATTTGAAAGAAATTATTAGCCAAAGAGGAACTTTAGAGAATTCTAATTCTCCTGTGCCAGAGTTTAGCCATGGGATTGGTATTAGTAACGCTGACTCACAGTCTACTTGTGATGCAGAAAGAGGAAACTCAGAGCAGGCGGAAATGAGAGCTGTCACTCCTGAAAACCATGAATCGATGACAAGTATATTTCCCAGTGCTGCTGTGGGTCTAAAGAATAATAATGACATACTTCCTAACAGCCAGGAAGAACTTTTATATAGCAGTAAGCAGTCCTTTCCAGGTATTCTAAAAGCTACTACTCCTAAAGATATGAGTGAAACAGAAAAAAACCTAGTAGTCACAGAGACTGGAGACAACATACATTCTCCTTCACATTTCTCTGATATTTTTAACTTTGTATCTAGTACTTCAAATCTTGAATTAAATGAAGAAATTTATTTTACTGATTCTCTTGAAATAAAGAGAAATGAAAATTTTCCAAAGGATTATGTGAAATTTTCAGATGAAGAAGAATTTATGAATGAAGATGAGAAGGAAATGAAGGAAATTCTAATGGCAGGAAGTAGTTTATCAGCTGGAGTTAGTGGGGAAGATAAAACCGAGATATTGAATCCCACTCCAGCGATGGCCAAATCTCTGACCATAGACTGTCTGGAATTGGCATTACCCCCTGAACTGGCTTTTCAACTTAATGAATTATTTGGTCCTGTTGGTATTGATTCAGGGTCTCTAACAGTTGAAGATTGTGTGGTTCATATAGATCTGAATCTGGCGAAAGTGATTCATGAGAAATGGAAAGAATCTGTAATGGAGCGACAAAGACAAGAAGAGGTGTCTTGTGGCAAGTTTATGCAAGATCCTTCCTTGGTTGGACATACTGGGCTTGATAATCCTGAACAAAAATCATCTCAGAGAACAGGCAAAAAATTACTGAAGACTTTAACAGCATCTGAAATGCTACCTTTATTGGATCATTGGAATACTCAAACTAAAAAAGTATCACTCAGAGAAATAATGTCAGAAGAAATTGCCTTACAGGAAAAACATAATTTGAAAAGGGAGACCCTTATGTTTGAAAAAGATTGTGCCACTAAACTAAAGGAGAAGCAGCTCTTTAAGATATTTCCAGCCATTAACCAAAATTTTCTGGTGGACATTTTCAAGGACCACAACTATTCATTAGAACACACAGTGCAATTTCTTAACTGTGTTCTTGAAGGGGACCCTGTAAAAACAGTTGTAGCCCAAGAGTTTGTTCACCAAAATGAGAATGTCACATCTCATACTGGCCAGAAGTCTAAAGAGAAAAAGCCAAAGAAATTAAAAGAGACTGAAGAAACACCAAGTGAACTGTCTTTCCAGGACTTTGAGTACCCAGACTATGATGACTACAGAGCAGAGGCTTTCCTTCACCAACAGAAGAGGATGGAGTGCTACAGCAAGGCCAAAGAAGCTTATCGGATAGGGAAAAAAAATGTCGCCACCTTTTATGCCCAGCAGGGTACTCTTCATGAGCAGAAGATGAAAGAAGCCAATCACCTTGCTGCCATAGAGATCTTTGAGAAAGTCAATGCTTCGCTGCTGCCACAGAATGTTTTAGACCTCCATGGGCTGCATGTGGATGAAGCTCTAGAACATTTGATGAGAGTTTTAGAGAAGAAGACTGAAGAATTTAAGCAGAACGGTGGGAAGCCCTATTTGTCTGTGATTACGGGGAGAGGAAACCACAGCCAGGGAGGAGTTGCTCGCATCAAACCAGCTGTCATTAAGTACCTCATAAGCCATAGCTTCAGGTTCTCTGAAATTAAACCAGGGTGCTTGAAAGTCATGCTAAAGTAAAATAAACATCCTTGAATTAGAAGTATGAAGAATTTAATAGAGAAACAAGGCTAGAACACATCTACATCCTGAAGAGCCGTTTATAACTTCATATTATATGATGACAAAGTTCATTATTTTCCTTAAAGTTGAGCAATTGACTTTTATGGTCCAATGATGAACTTATTATTAATAAATGATTGAGTTAACTGTGAGGCTTCTCATTAAAATACAATATTGCAGCTATCAGTTGGAGAATATATTATAAAATTTTCAGACAGTATATCAGAAAAATGTTTTTATTTGTACTGTATAGAAAATGTAATTTTGCTGTTAACTCTGTACTTTTTAAATTGAAAATGTTTTATAAATTTGCTTTTAAATTTTCTTATGAAGCCATTTGCAAATTACATACTTAATTTAATAAAATACTTTAGCCACA