Summary

Gene Name	PYY
Specie	Homo sapiens
Full Name	peptide YY
Also known as	PYY-I|PYY1
Coordinate	chr17:43952733-44004445
Strand	-
Gene summary	This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]

Retrocopy(s) from PYY

Retroname	Coord	Strand	Genomic Region	ENSG
PYY3	chrX:50156065-50156338	+	Intergenic	ENSG00000181977	UCSC

Expression

Transcript Sequences

>NM_004160.6

ATCGGTCATGGGGCCGAGACTAAATGTGGCGGGTTGTCTTTAATCTGCTGCCAAGAGGAAACTCATTCAGGCAAGTTCAGCCCTTTATGAGGAATTCCCCTGTGGTCACATTCCAATTCCTGGACCTGCTGCCACCCTCAGAACTGCATGCTCCTTCTTCAGACTTTCTAAGAATGACTCAGGTCATTGGTGGAGTGAAGTCAAGATTTCCAACTCAGTCACCTGAAGAGATGGAGATACCATTCATGGAGCTGGAGGTCCCTGGAGATTTGGGAATTCAGATAACAAGCTAAGATAAGGagtttgcctacctctgTCCTAGAGCGAAGCCTGAGCCTTGGGCGCGCAGCACACCACAAGTATCTGTTACTGTGTTTTGCAGAAGCTTCAGGCGGGGATATAAGCCCCACAAGGAAAGCGCTGAGCAGAGGAGGCCTCAGCTTGACCTGCGGCAGTGCAGCCCTTGGGACTTCCCTCGCCTTCCACCTCCTGCTCGTCTGCTTCACAAGCTATCGCTATGGTGTTCGTGCGCAGGCCGTGGCCCGCCTTGACCACAGTGCTTCTGGCCCTGCTCGTCTGCCTAGGGGCGCTGGTCGACGCCTACCCCATCAAACCCGAGGCTCCCCGCGAAGACGCCTCGCCGGAGGAGCTGAACCGCTACTACGCCTCCCTGCGCCACTACCTCAACCTGGTCACCCGGCAGCGGTATGGGAAAAGAGACGGCCCGGACACGCTTCTTTCCAAAACGTTCTTCCCCGACGGCGAGGACCGCCCCGTCAGGTCGCGGTCGGAGGGCCCAGACCTGTGGTGAGGACCCCTGAGGCCTCCTGGGAGATCTGCCAACCACGCCCACGTCATTTGCATACGCACTCCCGACCCCAGAAACCCGGATTCTGCCTCCCGACGGCGGCGTCTGGGCAGGGTTCGGGTGCGGCCCTCCGCCCGCGTCTCGGTGCCCCCGCCCCCTGGGCTGGAGGGCTGTGTGTGGTCCTTCCCTGGTCCCAAAATAAAGAGCAAATTCCACAGAAACGGAA