Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Gene Name RGS10
Plot displaying the genomic locations of a parental gene (in chr10) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name regulator of G protein signaling 10
Also known as -
Coordinate chr10:119499817-119542719
Strand -
Gene summary Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Retrocopy(s) from RGS10

Retroname Coord Strand Genomic Region ENSG
RGS10P1 chr8:73831150-73831381 + Intragenic
ENSG00000253273 UCSC

Expression

Transcript Sequences

>NM_001005339.2
ctcctcctcctcctcgccttcctccggctcagccgccgcgccgccgggctgctccttcttcctcctcGGGCGCCCGCGGCGATGTTCAACCGCGCCGTGAGCCGGCTGAGCAGGAAGCGGCCGCCGTCAGACATCCACGACAGCGATGGCAGTTCCAGCAGCAGCCACCAGAGCCTCAAGAGCACAGCCAAATGGGCGGCATCCCTGGAGAATCTGCTGGAAGACCCAGAAGGCGTGAAAAGATTTAGGGAATTTTTAAAAAAGGAATTCAGTGAAGAAAATGTTTTGTTTTGGCTAGCATGTGAAGATTTTAAGAAAATGCAAGATAAGACGCAGATGCAGGAAAAGGCAAAGGAGATCTACATGACCTTTCTGTCCAGCAAGGCCTCATCACAGGTCAACGTGGAGGGGCAGTCTCGGCTCAACGAGAAGATCCTGGAAGAACCGCACCCTCTGATGTTCCAGAAACTCCAGGACCAGATCTTTAATCTCATGAAGTACGACAGCTACAGCCGCTTCTTAAAGTCTGACTTGTTTTTAAAACACAAGCGAACCGAGGAAGAGGAAGAAGATTTGCCTGATGCTCAAACTGCAGCTAAAAGAGCTTCCAGAATTTATAACACATGAGCCCCCAAAAAGCCGGGACTGGCAGCTTTAAGAAGCAAAGGAATTTCCTCTCAGGACCGTGCCGGGTTTATCATTGCTTTGTTATTTGTAAGGACTGAAATGTACAAAACCCTTCAATGGGATGTGTGTTTTATTAACTGCTTCACCAGTAAATTTTGCATGATGGCTAAGCTAACATAAAAAAAGAATAATAATAACTTGGAAGTTTTAGTTTACAAAACAGAGATTCCTTCAACACTGGACACGTCGAGCATTTTGTAGCTTAATTAAACCTCATGTAAGGCCACAAGGTGAAA