Summary

Gene Name	SSX1
Specie	Homo sapiens
Full Name	SSX family member 1
Also known as	CT5.1|SSRC
Coordinate	chrX:48255392-48267444
Strand	+
Gene summary	The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013]

Retrocopy(s) from SSX1

Retroname	Coord	Strand	Genomic Region	ENSG
SSXP10	chr6:118589033-118590175	+	Intragenic	ENSG00000217330	UCSC

Expression

Transcript Sequences

>NM_005635.4

ACCACTGCTGCCGACCTCGCAACCACTGCTTTGTCTCTGAAGTGAGACTGCTCCTGGTGCCATGAACGGAGACGACACCTTTGCAAAGAGACCCAGGGATGATGCTAAAGCATCAGAGAAGAGAAGCAAGGCCTTTGATGATATTGCCACATACTTCTCTAAGAAAGAGTGGAAAAAGATGAAATACTCGGAGAAAATCAGCTATGTGTATATGAAGAGAAACTATAAGGCCATGACTAAACTAGGTTTCAAAGTCACCCTCCCACCTTTCATGTGTAATAAACAGGCCACAGACTTCCAGGGGAATGATTTTGATAATGACCATAACCGCAGGATTCAGGTTGAACATCCTCAGATGACTTTCGGCAGGCTCCACAGAATCATCCCGAAGATCATGCCCAAGAAGCCAGCAGAGGACGAAAATGATTCGAAGGGAGTGTCAGAAGCATCTGGCCCACAAAACGATGGGAAACAACTGCACCCCCCAGGAAAAGCAAATATTTCTGAGAAGATTAATAAGAGATCTGGACCCAAAAGGGGGAAACATGCCTGGACCCACAGACTGCGTGAGAGAAAGCAGCTGGTGATTTATGAAGAGATCAGTGACCCTGAGGAAGATGACGAGTAACTCCCCTGGGGGATACGACACATGCCCTTGATGAGAAGCAGAACGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGCTCCCTCGTCATCAGGTGCATAGCAAGTGAAAGCAAGTGTTCACAACGGTGAAACTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGTGTTTCCATTGTATTTTCTTACAGTGTGCCATTCTGTTAGATACTATCCTTATAATTGATGAGCAAGACATACTGAATGCATATTTCGGTTTGTGTATCCATGCACCTACGTCAGAAAACAAGTATTGTCAGGTATTCTCTCCATAGAACAGCACTATCCTCATctctccccagatgtgactactgagggcagttctgagtgtttaatttcagactttttcctctgcatttacacacacacacacacacacacgcacacacacacacCAAGTACCAGTATAAGCATCTCCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCCCCCCTCACTCTGTTTCCTGTTCAGCATGTACTCCCCTCATCCGATTCCCCTGTATCAGTCACTGACAGTTAATAAACCTTTGCAAACGTTC