Summary

Gene Name	UBTF
Specie	Homo sapiens
Full Name	upstream binding transcription factor
Also known as	CONDBA|NOR-90|UBF|UBF-1|UBF1|UBF2
Coordinate	chr17:44205036-44221304
Strand	-
Gene summary	This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]

Retrocopy(s) from UBTF

Retroname	Coord	Strand	Genomic Region	ENSG
UBTFL11	chrX:38531974-38532758	-	Intergenic	ENSG00000233007	UCSC
UBTFL8	chr3:5080780-5081272	-	Intergenic	ENSG00000224082	UCSC

Expression

Transcript Sequences

>NM_001076684.3

GTGCTTTTCGCCGCGAGGAGCAGCAGgcagcagccacagccgccgccgccgccgccgccgccacagcagcagcagccgccgccccagcgccgccgcctcgcccggaggaggagccgctgccgccgcGGGAGGGAGCTGCGGCTGTGCCCGGCCGAGCGGGGGAGGGCGCCGCCACTCAGAGCCAGGGAGGGAGCCGCTGGAGCGGGAAGCCCGGAGGCCGCGCTGCGCCGGGGTGAGGTGGCTTTGACCCCGGGTTGCCCGGCCAGCACGACCGAGGAGGTGGCTGGACAGCTGGAGGATGAACGGAGAAGCCGACTGCCCCACAGACCTGGAAATGGCCGCCCCCAAAGGCCAAGACCGTTGGTCCCAGGAAGACATGCTGACTTTGCTGGAATGCATGAAGAACAACCTTCCATCCAATGACAGCTCCAAGTTCAAAACCACCGAATCACACATGGACTGGGAAAAAGTAGCATTTAAAGACTTTTCTGGAGACATGTGCAAGCTCAAATGGGTGGAGATTTCTAATGAGGTGAGGAAGTTCCGTACATTGACAGAATTGATCCTCGATGCTCAGGAACATGTTAAAAATCCTTACAAAGGCAAAAAACTCAAGAAACACCCAGACTTCCCAAAGAAGCCCCTGACCCCTTATTTCCGCTTCTTCATGGAGAAGCGGGCCAAGTATGCGAAACTCCACCCTGAGATGAGCAACCTGGACCTAACCAAGATTCTGTCCAAGAAATACAAGGAGCTTCCGGAGAAGAAGAAGATGAAATATATTCAGGACTTCCAGAGAGAGAAACAGGAGTTCGAGCGAAACCTGGCCCGATTCAGGGAGGATCACCCCGACCTAATCCAGAATGCCAAGAAATCGGACATCCCAGAGAAGCCCAAAACCCCCCAGCAGCTGTGGTACACCCACGAGAAGAAGGTGTATCTCAAAGTGCGGCCAGATGAGATCATGAGAGACTATATCCAGAAGCACCCAGAGCTGAACATCAGTGAGGAGGGTATCACCAAGTCCACCCTCACCAAGGCCGAACGCCAGCTCAAGGACAAGTTTGACGGGCGACCCACCAAGCCACCTCCGAACAGCTACTCGCTGTACTGCGCAGAGCTCATGGCCAACATGAAGGACGTGCCCAGCACAGAGCGCATGGTGCTGTGCAGCCAGCAGTGGAAGCTGCTGTCCCAGAAGGAGAAGGACGCCTATCACAAGAAGTGTGATCAGAAAAAGAAAGATTACGAGGTGGAGCTGCTCCGTTTCCTCGAGAGCCTGCCTGAGGAGGAGCAGCAGCGGGTCTTGGGGGAAGAGAAGATGCTGAACATCAACAAGAAGCAGGCCACCAGCCCCGCCTCCAAGAAGCCAGCCCAGGAAGGGGGCAAGGGCGGCTCCGAGAAGCCCAAGCGGCCCGTGTCGGCCATGTTCATCTTCTCGGAGGAGAAACGGCGGCAGCTGCAGGAGGAGCGGCCTGAGCTCTCCGAGAGCGAGCTGACCCGCCTGCTGGCCCGAATGTGGAACGACCTGTCTGAGAAGAAGAAGGCCAAGTACAAGGCCCGAGAGGCGGCGCTCAAGGCTCAGTCGGAGAGGAAGCCCGGCGGGGAGCGCGAGGAACGGGGCAAGCTGCCCGAGTCCCCCAAAAGAGCTGAGGAGATCTGGCAACAGAGCGTTATCGGCGACTACCTGGCCCGCTTCAAGAATGACCGGGTGAAGGCCTTGAAAGCCATGGAAATGACCTGGAATAACATGGAAAAGAAGGAGAAACTGATGTGGATTAAGAAGGCAGCCGAAGACCAAAAGCGATATGAGAGAGAGCTGAGTGAGATGCGGGCACCTCCAGCTGCTACAAATTCTTCCAAGAAGATGAAATTCCAGGGAGAACCCAAGAAGCCTCCCATGAACGGTTACCAGAAGTTCTCCCAGGAGCTGCTGTCCAATGGGGAGCTGAACCACCTGCCGCTGAAGGAGCGCATGGTGGAGATCGGCAGTCGCTGGCAGCGCATCTCCCAGAGCCAGAAGGAGCACTACAAAAAGCTGGCCGAGGAGCAGCAAAAGCAGTACAAGGTGCACCTGGACCTCTGGGTTAAGAGCCTGTCTCCCCAGGACCGTGCAGCATATAAAGAGTACATCTCCAATAAACGTAAGAGCATGACCAAGCTGCGAGGCCCAAACCCCAAATCCAGCCGGACTACTCTGCAGTCCAAGTCGGAGTCCgaggaggatgatgaagaggatgaggatgacgaggacgaggatgaagaagaggaagatgatgagaatggggaCTCCTCTGAAGATGGCGGCGACTCCTCTGAGTCCAGCAGCGAGGACGAGAGCGAGGATGGGGATGAGaatgaagaggatgacgaggacgaagacgacgacgaggatgacgatgaggatgaagatAATGAGTCCGAGGGCAGCAGCTCCAGCTCCTCCTCCTCAGGGGACTCCTCAGACTCTGACTCCAACTGAGGCTCAGCCCCACCCCAGGGCAGCCAGGGAGAGCCCAGGAGCTCCCCTCCCCAACTGACCACCTTTGTTTCTCCCCCATGTTCTGTCCCTTGCCCCCCTGGCCTCCCCCACTTTCTTTCTTTCTTTAAAAAAAAAAAAAAATACGGTGGGGGTAGGGGGCTGGAGGAGCCCAGGCCAGGACTCTGCAGCCTCAGAGACATCAGCCCTTGGGGGTCCTCCTCCAGGGACAGCAACTATCAGACTAAGCCAGCACCGGACCAGCCTGGCCCACCCCACCCACTTCTGCACTTGCGGTTCCGGCATGGACAATGGACCGGAGAGTGGGGGTGGGGGGTCCCAAAGAGTTTGATGAGGCCCTCCACACCTGCGGCCCAATCCAAGGTGGGGTGGAAGCTTGGGGAAGACCCATTCCTTCCCAGAGGGGCCTGCCACCTGGACCCCTGCATTGGAACTGGAGGCAGGGAACATGGGGAGGAGGAGGGTCGGTGCCTTCAAGAAAACAGGCACTGCCCTGGTGGCCCTCTCCCCTGCCCCCTGCAGGAAGGAGCTGCCTGGACCCGTTCATGGGGGAGGGGGCAGAAGTGTTTTTTATATATGTGTATATATTTTTTTTTAAGCTCTGAGCTGTCAACGAGACGTTTCCTACCGATCTCGGCTGCCGTCTCTGTTGTCATTTCTGGGAGAGGGAGGGTTTAGGGGTAGATTTGGAACCTTTTAAAAATGGTCTTGATGTATGTGGAAGAGAGTATGTGTATGTGTGTTCCTGTACATAGCATGGGTGCAGCTGTGGATGTGTGCAAAAGAgtgtgagtgtgtgtgtgtgtgtgtAAAGGGGTCTGTCCTAGAGCCCACATCAGTTTGTTGTGAATCTGGAAAAAGGGTCGGTGAGGGCCGGGAGATGTTGACCCTGGTGGGAGCAGGCTGAGGCTGCCCCGTTCTCCACATCCTCTGTTTTGCCCAGTCTCTGATTCCATTAGGGGGAGTGTGCTGAAGCCATTCTCGGATGCTTCCCAGACCAGGCTCCCTCTGCCAGAGTCACATGCATCCGAGCTGCTGGTCTCCATTGTCCAGCAGGAAGGCGGAAAGGCAGGCAAGATGGTGTGAAGCTTAAAGCTTGTATTTGATGGAAAAGGTCTCCCCTGTTCATCTGAGAGGCCAAGCCTGGCCACCCCAGGCTCAGAACCTGGGCTTCAAGAAATGTGCTGGGAGCTCCTAACTTACACATCCCTCCAGCCTTCCTTGAATCCTCCCACCACCCCCTATTTCCTTTAATTTCTCAGGTCTGCTCCCTCCTCCCCCAACCCCACAGCTGGGCAAGAAGTCTGCAAAAGCTGCATCTGCAGCTGTCTCTAACTCTTCCCAGCCATCTCCCGTATTTTTTGGTACCTTGATTCCTTGACTCTTAATAAGCCAAGCCACCTTATCTCTGTAGTTCTTATTTTTTTGTTGACTAAATTTGGGGGGTTCTTTTTTATGGTCATGTCACTGACCTATTAAATTGGGGCTTGGTGCTTTTCCACCTTCCCCCTCTGAATGAAAGCCAAGGAATGGGGGAAGAGCGGGAACTCTGCCGCGGAGGTGGAGCAAGAACGGTGAAGGGCCCTGGTCCCAGAGAGGCTGGTGGGTCCCTCTCCCAAAGGAAGGCAGACAGTCTCTGCTTTGCCTTGGACCTTGGTGCTGGGGGTGGGGAGGCCTGGGGGGGACACTCCCCACTCCCATTCCCCTTCCTTTGTCCTAATCCTGGAATTAAGTACAGGGGTTTATAGGTTCTATTTCTTCCCAAGAGCCCTGCAAAGAACCCCAGTTTCCTATTTGGATGCCCCTACACTGTTGTGTTTCAGTGGAATGTATTTTCATTTAAAAACAACTTTGAATGGGGCACTTTTTCTTTCCTGTTTTAAAAATTGAAAAATTCTTACAGTACAAACAGGACTGTCAGGGTGGGGGTGTTGGTGCTGTAAGAGGTCACTCTTGAGTGCATTTTGGCACTGGGATGGGATGGCTGGGGTGGGAAGACCCCCATCCCCACCCCCAACTTCTTTTCTAATATTTAAGGAGTGTTTTGTAGGATTCAACAACCACCACAACTTGAATTTGTATCATGGGAGGTGGGAGGGAGTGGCTTAGAGGTGTCTGCCTATGCTTAAAGCCAACTGTGGAAGTTTTGTTTTCCCTTTTTTGTATAATAAAGTGAAAAACAAA

>NM_014233.4

GTGCTTTTCGCCGCGAGGAGCAGCAGgcagcagccacagccgccgccgccgccgccgccgccacagcagcagcagccgccgccccagcgccgccgcctcgcccggaggaggagccgctgccgccgcGGGAGGGAGCTGCGGCTGTGCCCGGCCGAGCGGGGGAGGGCGCCGCCACTCAGAGCCAGGGAGGGAGCCGCTGGAGCGGGAAGCCCGGAGGCCGCGCTGCGCCGGGGTGAGGTGGCTTTGACCCCGGGTTGCCCGGCCAGCACGACCGAGGAGGTGGCTGGACAGCTGGAGGATGAACGGAGAAGCCGACTGCCCCACAGACCTGGAAATGGCCGCCCCCAAAGGCCAAGACCGTTGGTCCCAGGAAGACATGCTGACTTTGCTGGAATGCATGAAGAACAACCTTCCATCCAATGACAGCTCCAAGTTCAAAACCACCGAATCACACATGGACTGGGAAAAAGTAGCATTTAAAGACTTTTCTGGAGACATGTGCAAGCTCAAATGGGTGGAGATTTCTAATGAGGTGAGGAAGTTCCGTACATTGACAGAATTGATCCTCGATGCTCAGGAACATGTTAAAAATCCTTACAAAGGCAAAAAACTCAAGAAACACCCAGACTTCCCAAAGAAGCCCCTGACCCCTTATTTCCGCTTCTTCATGGAGAAGCGGGCCAAGTATGCGAAACTCCACCCTGAGATGAGCAACCTGGACCTAACCAAGATTCTGTCCAAGAAATACAAGGAGCTTCCGGAGAAGAAGAAGATGAAATATATTCAGGACTTCCAGAGAGAGAAACAGGAGTTCGAGCGAAACCTGGCCCGATTCAGGGAGGATCACCCCGACCTAATCCAGAATGCCAAGAAATCGGACATCCCAGAGAAGCCCAAAACCCCCCAGCAGCTGTGGTACACCCACGAGAAGAAGGTGTATCTCAAAGTGCGGCCAGATGCCACTACGAAGGAGGTGAAGGACTCCCTGGGGAAGCAGTGGTCTCAGCTCTCGGACAAAAAGAGGCTGAAATGGATTCATAAGGCCCTGGAGCAGCGGAAGGAGTACGAGGAGATCATGAGAGACTATATCCAGAAGCACCCAGAGCTGAACATCAGTGAGGAGGGTATCACCAAGTCCACCCTCACCAAGGCCGAACGCCAGCTCAAGGACAAGTTTGACGGGCGACCCACCAAGCCACCTCCGAACAGCTACTCGCTGTACTGCGCAGAGCTCATGGCCAACATGAAGGACGTGCCCAGCACAGAGCGCATGGTGCTGTGCAGCCAGCAGTGGAAGCTGCTGTCCCAGAAGGAGAAGGACGCCTATCACAAGAAGTGTGATCAGAAAAAGAAAGATTACGAGGTGGAGCTGCTCCGTTTCCTCGAGAGCCTGCCTGAGGAGGAGCAGCAGCGGGTCTTGGGGGAAGAGAAGATGCTGAACATCAACAAGAAGCAGGCCACCAGCCCCGCCTCCAAGAAGCCAGCCCAGGAAGGGGGCAAGGGCGGCTCCGAGAAGCCCAAGCGGCCCGTGTCGGCCATGTTCATCTTCTCGGAGGAGAAACGGCGGCAGCTGCAGGAGGAGCGGCCTGAGCTCTCCGAGAGCGAGCTGACCCGCCTGCTGGCCCGAATGTGGAACGACCTGTCTGAGAAGAAGAAGGCCAAGTACAAGGCCCGAGAGGCGGCGCTCAAGGCTCAGTCGGAGAGGAAGCCCGGCGGGGAGCGCGAGGAACGGGGCAAGCTGCCCGAGTCCCCCAAAAGAGCTGAGGAGATCTGGCAACAGAGCGTTATCGGCGACTACCTGGCCCGCTTCAAGAATGACCGGGTGAAGGCCTTGAAAGCCATGGAAATGACCTGGAATAACATGGAAAAGAAGGAGAAACTGATGTGGATTAAGAAGGCAGCCGAAGACCAAAAGCGATATGAGAGAGAGCTGAGTGAGATGCGGGCACCTCCAGCTGCTACAAATTCTTCCAAGAAGATGAAATTCCAGGGAGAACCCAAGAAGCCTCCCATGAACGGTTACCAGAAGTTCTCCCAGGAGCTGCTGTCCAATGGGGAGCTGAACCACCTGCCGCTGAAGGAGCGCATGGTGGAGATCGGCAGTCGCTGGCAGCGCATCTCCCAGAGCCAGAAGGAGCACTACAAAAAGCTGGCCGAGGAGCAGCAAAAGCAGTACAAGGTGCACCTGGACCTCTGGGTTAAGAGCCTGTCTCCCCAGGACCGTGCAGCATATAAAGAGTACATCTCCAATAAACGTAAGAGCATGACCAAGCTGCGAGGCCCAAACCCCAAATCCAGCCGGACTACTCTGCAGTCCAAGTCGGAGTCCgaggaggatgatgaagaggatgaggatgacgaggacgaggatgaagaagaggaagatgatgagaatggggaCTCCTCTGAAGATGGCGGCGACTCCTCTGAGTCCAGCAGCGAGGACGAGAGCGAGGATGGGGATGAGaatgaagaggatgacgaggacgaagacgacgacgaggatgacgatgaggatgaagatAATGAGTCCGAGGGCAGCAGCTCCAGCTCCTCCTCCTCAGGGGACTCCTCAGACTCTGACTCCAACTGAGGCTCAGCCCCACCCCAGGGCAGCCAGGGAGAGCCCAGGAGCTCCCCTCCCCAACTGACCACCTTTGTTTCTCCCCCATGTTCTGTCCCTTGCCCCCCTGGCCTCCCCCACTTTCTTTCTTTCTTTAAAAAAAAAAAAAAATACGGTGGGGGTAGGGGGCTGGAGGAGCCCAGGCCAGGACTCTGCAGCCTCAGAGACATCAGCCCTTGGGGGTCCTCCTCCAGGGACAGCAACTATCAGACTAAGCCAGCACCGGACCAGCCTGGCCCACCCCACCCACTTCTGCACTTGCGGTTCCGGCATGGACAATGGACCGGAGAGTGGGGGTGGGGGGTCCCAAAGAGTTTGATGAGGCCCTCCACACCTGCGGCCCAATCCAAGGTGGGGTGGAAGCTTGGGGAAGACCCATTCCTTCCCAGAGGGGCCTGCCACCTGGACCCCTGCATTGGAACTGGAGGCAGGGAACATGGGGAGGAGGAGGGTCGGTGCCTTCAAGAAAACAGGCACTGCCCTGGTGGCCCTCTCCCCTGCCCCCTGCAGGAAGGAGCTGCCTGGACCCGTTCATGGGGGAGGGGGCAGAAGTGTTTTTTATATATGTGTATATATTTTTTTTTAAGCTCTGAGCTGTCAACGAGACGTTTCCTACCGATCTCGGCTGCCGTCTCTGTTGTCATTTCTGGGAGAGGGAGGGTTTAGGGGTAGATTTGGAACCTTTTAAAAATGGTCTTGATGTATGTGGAAGAGAGTATGTGTATGTGTGTTCCTGTACATAGCATGGGTGCAGCTGTGGATGTGTGCAAAAGAgtgtgagtgtgtgtgtgtgtgtgtAAAGGGGTCTGTCCTAGAGCCCACATCAGTTTGTTGTGAATCTGGAAAAAGGGTCGGTGAGGGCCGGGAGATGTTGACCCTGGTGGGAGCAGGCTGAGGCTGCCCCGTTCTCCACATCCTCTGTTTTGCCCAGTCTCTGATTCCATTAGGGGGAGTGTGCTGAAGCCATTCTCGGATGCTTCCCAGACCAGGCTCCCTCTGCCAGAGTCACATGCATCCGAGCTGCTGGTCTCCATTGTCCAGCAGGAAGGCGGAAAGGCAGGCAAGATGGTGTGAAGCTTAAAGCTTGTATTTGATGGAAAAGGTCTCCCCTGTTCATCTGAGAGGCCAAGCCTGGCCACCCCAGGCTCAGAACCTGGGCTTCAAGAAATGTGCTGGGAGCTCCTAACTTACACATCCCTCCAGCCTTCCTTGAATCCTCCCACCACCCCCTATTTCCTTTAATTTCTCAGGTCTGCTCCCTCCTCCCCCAACCCCACAGCTGGGCAAGAAGTCTGCAAAAGCTGCATCTGCAGCTGTCTCTAACTCTTCCCAGCCATCTCCCGTATTTTTTGGTACCTTGATTCCTTGACTCTTAATAAGCCAAGCCACCTTATCTCTGTAGTTCTTATTTTTTTGTTGACTAAATTTGGGGGGTTCTTTTTTATGGTCATGTCACTGACCTATTAAATTGGGGCTTGGTGCTTTTCCACCTTCCCCCTCTGAATGAAAGCCAAGGAATGGGGGAAGAGCGGGAACTCTGCCGCGGAGGTGGAGCAAGAACGGTGAAGGGCCCTGGTCCCAGAGAGGCTGGTGGGTCCCTCTCCCAAAGGAAGGCAGACAGTCTCTGCTTTGCCTTGGACCTTGGTGCTGGGGGTGGGGAGGCCTGGGGGGGACACTCCCCACTCCCATTCCCCTTCCTTTGTCCTAATCCTGGAATTAAGTACAGGGGTTTATAGGTTCTATTTCTTCCCAAGAGCCCTGCAAAGAACCCCAGTTTCCTATTTGGATGCCCCTACACTGTTGTGTTTCAGTGGAATGTATTTTCATTTAAAAACAACTTTGAATGGGGCACTTTTTCTTTCCTGTTTTAAAAATTGAAAAATTCTTACAGTACAAACAGGACTGTCAGGGTGGGGGTGTTGGTGCTGTAAGAGGTCACTCTTGAGTGCATTTTGGCACTGGGATGGGATGGCTGGGGTGGGAAGACCCCCATCCCCACCCCCAACTTCTTTTCTAATATTTAAGGAGTGTTTTGTAGGATTCAACAACCACCACAACTTGAATTTGTATCATGGGAGGTGGGAGGGAGTGGCTTAGAGGTGTCTGCCTATGCTTAAAGCCAACTGTGGAAGTTTTGTTTTCCCTTTTTTGTATAATAAAGTGAAAAACAAA