Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Gene Name CAPNS1
Plot displaying the genomic locations of a parental gene (in chr19) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name calpain small subunit 1
Also known as CALPAIN4|CANP|CANPS|CAPN4|CDPS|CSS1
Coordinate chr19:36140066-36150353
Strand +
Gene summary This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Retrocopy(s) from CAPNS1

Retroname Coord Strand Genomic Region ENSG
CAPNS1P1 chr1:89394042-89394782 + Intergenic
 ENSG00000215874 UCSC

Expression

Transcript Sequences

>NM_001302632.2
GAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGAGCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAGACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGggcggcggcggcggcggcgggggaggcgggggcCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGggcggcggcggcggcggcggcggcggcggcggtggtggaggcggcggtggcggTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCAGTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACGACACCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGGCTTTGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTGCAGTAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGAAAGTGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGGCACTGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCTTGCTATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTTTTGTTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAACAAGCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCACTTGTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTGCTACCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGAGGAAATAAACATGCCCCAGTTGCTGATCTCTA