Summary

Gene Name	PLA2G10
Specie	Homo sapiens
Full Name	phospholipase A2 group X
Also known as	GXPLA2|GXSPLA2|SPLA2|sPLA2-X
Coordinate	chr16:14672548-14694662
Strand	-
Gene summary	This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]

Retrocopy(s) from PLA2G10

Retroname	Coord	Strand	Genomic Region	ENSG
PLA2G10P1	chr3:182691936-182692330	+	Intergenic	ENSG00000243378	UCSC

Expression

Transcript Sequences

>NM_003561.3_2

GTGACAGCCGGGGTGTGTGTCCGCCGGGCTTGGTGCCTCCGGTGGCCCTGCAGCACCGTCCCACCTCTGCCACCCTCCGATGGGGCCGCTACCTGTGTGCCTGCCAATCAtgctgctcctgctactgccgtcgctgctgctgctgctgcttctACCTGGCCCCGGGTCCGGCGAGGCCTCCAGGATATTACGTGTGCACCGGCGTGGGATCCTGGAACTGGCAGGAACTGTGGGTTGTGTTGGTCCCCGAACCCCCATCGCCTATATGAAATATGGTTGCTTTTGTGGCTTGGGAGGCCATGGCCAGCCCCGCGATGCCATTGACTGGTGCTGCCATGGCCACGACTGTTGTTACACTCGAGCTGAGGAGGCCGGCTGCAGCCCCAAGACAGAGCGCTACTCCTGGCAGTGCGTCAATCAGAGCGTCCTGTGCGGACCGGCAGAGAACAAATGCCAAGAACTGTTGTGCAAGTGTGACCAGGAGATTGCTAACTGCTTAGCCCAAACTGAGTACAACTTAAAGTACCTCTTCTACCCCCAGTTCCTATGTGAGCCGGACTCGCCCAAGTGTGACTGACTACCTTGACTTGAAATGCTCTTTTGCACAAGGAAATAAAGCGTCCTCTCAGTAATGAA