Retrocopy Name | PLA2G10P1 |
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Species | Homo sapiens | |
Coordinates (hg38) | chr3:182691936-182692330 UCSC | |
Coordinates (T2T) | chr3:185496818-185497212 UCSC | |
Coordinates (hg19) | chr3:182409724-182410118 UCSC | |
Strand | + | |
Parental Sequence | NM_003561.3_2 | |
Parental seq. overlap | 315 bp | |
Parental seq. overlap (%) | 49.3% | |
Genomic Region |
Intergenic |
|
Retrocopy Summary | PLA2G10P1, located on chr3:182691936-182692330, is a retrocopy of the parental gene PLA2G10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
Gene Name | PLA2G10 |
Full Name | phospholipase A2 group X |
Also known as | GXPLA2|GXSPLA2|SPLA2|sPLA2-X |
Coordinate | chr16:14672548-14694662 |
Strand | - |
Gene summary | This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015] |
Species | Scientific Name | Retrocopy | |
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Chimpanzee | Pan troglodytes | LOC112205828P1 |
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Bonobo | Pan paniscus | PLA2G10P1 |
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Gorilla | Gorilla gorilla | PLA2G10P1 |
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Orangutan | Pongo abelii | PLA2G10P1 |
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Gibbon | Nomascus leucogenys | PLA2G10P1 |
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Green monkey | Chlorocebus sabaeus | LOC103228738P1 |
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Crab-eating macaque | Macaca fascicularis | PLA2G10P1 |
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Rhesus | Macaca mulatta | LOC717517P1 |
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Baboon | Papio anubis | PLA2G10P1 |
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Golden snub-nosed monkey | Rhinopithecus roxellana | PLA2G10P1 |
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Marmoset | Callithrix jacchus | PLA2G10P1 |
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Mouse lemur | Microcebus murinus | Without Homology |
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Mouse | Mus musculus | Without Homology |
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Rat | Rattus norvegicus | Without Homology |
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Chinese hamster | Cricetulus griseus | Without Homology |
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Rabbit | Oryctolagus cuniculus | Without Homology |
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Pig | Sus scrofa | Without Homology |
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Cow | Bos taurus | Without Homology |
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Sheep | Ovis aries | Without Homology |
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Dolphin | Tursiops truncatus | Without Homology |
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Horse | Equus caballus | Without Homology |
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Dog | Canis familiaris | Without Homology |
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Panda | Ailuropoda melanoleuca | Without Homology |
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Cat | Felis catus | Without Homology |
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Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
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Velvety free-tailed bat | Molossus molossus | Without Homology |
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Greater mouse-eared bat | Myotis myotis | Without Homology |
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Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
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Greater horseshoe bat | Rhinolophus ferrumequinum | Without Homology |
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Egyptian rousette | Rousettus aegyptiacus | Without Homology |
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Sloth | Choloepus didactylus | Without Homology |
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Tasmanian Devil | Sarcophilus harrisii | Without Homology |
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Opossum | Monodelphis domestica | Without Homology |
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Platypus | Ornithorhynchus anatinus | Without Homology |
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Chicken | Gallus gallus | Without Homology |
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Turkey | Meleagris gallopavo | Without Homology |
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Zebra Finch | Taeniopygia guttata | Without Homology |
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Budgerigar | Melopsittacus undulatus | Without Homology |
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Painted Turtle | Chrysemys picta | Without Homology |
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Lizard | Anolis Carolinensis | Without Homology |
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Frog | Xenopus tropicalis | Without Homology |
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Zebrafish | Danio rerio | Without Homology |
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Drosophila | Drosophila melanogaster | Without Homology |
>PLA2G10P1 |
gGGATCTGGCCCTGGGTCCCGCCAGGCCTCCAAGAGGTCACACGTGCACCGACGTGGGATCCTGGAACTGGCAGGAACTGTGGGTTGTATTGACTCCTGAACCCCACTTACCTATATGAAATACAGTTGCTACTGTGGCCTGGGAGGCCATGGCCAGCACCGGGATGCCATTGACTGGACCAGCAGAGAACAAATGCCAAAAGCTCTTGTGCAAGTGTGACCAGGAGATTGCTAACTGCTTAGCCCGAACTGAGTACAACTGAAAGTACCTCTTCTACCCCCAGTTTCTGTGAAAGCAGGACTCGCCCAAGTGCGACTGGCTAGCTTGACTTGAAGTGCTCCTTTGCACAAAGAAATAAAGC |
>NM_003561.3_2 |
GTGACAGCCGGGGTGTGTGTCCGCCGGGCTTGGTGCCTCCGGTGGCCCTGCAGCACCGTCCCACCTCTGCCACCCTCCGATGGGGCCGCTACCTGTGTGCCTGCCAATCAtgctgctcctgctactgccgtcgctgctgctgctgctgcttctACCTGGCCCCGGGTCCGGCGAGGCCTCCAGGATATTACGTGTGCACCGGCGTGGGATCCTGGAACTGGCAGGAACTGTGGGTTGTGTTGGTCCCCGAACCCCCATCGCCTATATGAAATATGGTTGCTTTTGTGGCTTGGGAGGCCATGGCCAGCCCCGCGATGCCATTGACTGGTGCTGCCATGGCCACGACTGTTGTTACACTCGAGCTGAGGAGGCCGGCTGCAGCCCCAAGACAGAGCGCTACTCCTGGCAGTGCGTCAATCAGAGCGTCCTGTGCGGACCGGCAGAGAACAAATGCCAAGAACTGTTGTGCAAGTGTGACCAGGAGATTGCTAACTGCTTAGCCCAAACTGAGTACAACTTAAAGTACCTCTTCTACCCCCAGTTCCTATGTGAGCCGGACTCGCCCAAGTGTGACTGACTACCTTGACTTGAAATGCTCTTTTGCACAAGGAAATAAAGCGTCCTCTCAGTAATGAA |
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