| Gene Name | API5 |
|
| Specie | Homo sapiens | |
| Full Name | apoptosis inhibitor 5 | |
| Also known as | AAC-11|AAC11 | |
| Coordinate | chr11:43311970-43344530 | |
| Strand | + | |
| Gene summary | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| API5P2 | chr2:177994816-177998871 | - |
Intragenic |
ENSG00000213962 | UCSC |
| API5P1 | chrX:116104365-116108497 | - |
Intergenic |
ENSG00000234558 | UCSC |
| >XM_006718359.4 |
| GCAGCCGCGCTGTGCGCGGTGACTGGCGGCTGCACTGGCGGCAGCTGGAGGTGTAATAGTGCGGGTAGTGGGTTTGGAGAAGTTCCGAGGCGGCGGTGGCGCCGGTCAGGACAAGGATAGCGGAACCGGGCCCTGGGCTTGTCGCTCACCATGCCGACAGTAGAGGAGCTTTACCGCAATTATGGCATCCTGGCCGATGCCACGGAGCAAGTGGGCCAGCATAAAGATGCCTATCAAGTGATATTGGATGGTGTGAAAGGTGGTACTAAGGAAAAGCGATTAGCAGCTCAATTTATTCCGAAATTCTTTAAGCATTTTCCAGAATTGGCTGATTCTGCTATCAATGCACAGTTAGACCTCTGTGAGGATGAAGATGTATCTATTCGACGTCAAGCAATTAAAGAACTGCCTCAATTTGCCACTGGAGAAAATCTTCCTCGAGTGGCAGATATACTAACGCAACTTTTGCAGACAGATGACTCTGCAGAATTTAACCTAGTGAACAATGCCCTATTAAGTATATTTAAAATGGATGCAAAAGGGACTTTAGGTGGGTTGTTCAGCCAAATACTTCAAGGAGAGGACATTGTTAGAGAACGAGCAATTAAATTCCTTTCTACAAAACTTAAGACTTTACCAGATGAAGTCTTAACAAAGGAAGTGGAAGAGCTTATACTAACTGAATCCAAAAAGGTCCTAGAAGATGTGACTGGTGAAGAATTTGTTCTATTTATGAAGATACTGTCTGGGTTAAAAAGCTTACAGACAGTGAGTGGAAGACAGCAACTTGTAGAGTTGGTGGCTGAACAGGCCGACCTAGAACAGACCTTCAATCCCTCGGATCCTGACTGTGTGGACAGGCTCTTACAGTGCACTCGGCAGGCAGTACCCCTCTTCTCTAAAAATGTCCATTCCACAAGGTTTGTGACATATTTCTGTGAGCAGGTTCTCCCTAACCTCGGTACCTTGACTACCCCAGTGGAAGGTCTTGATATACAGTTGGAGGTATTGAAATTGTTGGCGGAGATGAGTTCATTTTGTGGTGACATGGAAAAACTAGAAACAAATTTAAGGAAACTATTTGATAAGTTATTGGAATACATGCCCCTCCCTCCAGAAGAGGCAGAAAATGGAGAGAATGCTGGTAATGAAGAACCCAAGCTACAGTTCAGTTATGTGGAATGTTTGTTGTACAGTTTTCACCAGTTGGGCCGAAAACTTCCAGATTTCTTAACAGCCAAACTGAATGCAGAAAAGCTCAAAGATTTCAAAATCAGGCTGCAGTACTTTGCACGGGGCCTGCAAGTTTATATCAGACAACTTCGCTTAGCTCTCCAGGGTAAAACGGGTGAGGCCTTAAAAACAGAAGAGAACAAGATTAAAGTCGTTGCATTGAAAATAACAAACAATATCAATGTTTTAATCAAGGATCTCTTCCACATTCCTCCTTCTTATAAGAGCACAGTAACACTATCCTGGAAACCTGTACAAAAGGTTGAGATTGGGCAAAAGAGAGCCAGTGAAGATACAACTTCAGGTTCACCACCCAAGAAATCTTCAGCAGGACCAAAAAGAGATGCCAGGCAGATTTATAACCCTCCCAGTGGGAAATATAGCAGCAATTTGGGCAACTTTAATTATGAAAGGGGGGTCAAAAAAGACATCAAGACATCACCCTAGTAAGACATAATGGCAAAAAAATTGATTGCAAAATTGACTGAAAAGGTATTTTTCAAGCCTCCAAGATTGTGGATCAAAAACAGCAAAACCAAGCTCTCTCTATTGTTGCTAACAAGATTGCTATAATGAGGAAGTTTAGAAGTTAATGAAGAGATTTGATCTCATTTACATATGATTAAAAGTCCAGCCTTGTGATAACTTCGATCAGTTTTCTTCATGGGACGACACCTTTGAGGACCATTTCTCTGTGGCTATAAAAGTGACTGACCAATGGATGAGAGACTCTTGTTCTGTACATCACAAGTGACTTGATTTTTCAGCAAAAGATATGCTTAGTTTATATCAGTAGCTGAAACACACTCAGACGCACATACACACATAGCACCTATTTGGCAGTATTCTGAGAAGCTTATGTAGCTGATAAAGCAGTGAAAAAAACTCAGCCTTTAGATCTACATTTGTGTGAGTCCAGTTGCGTGAAATACTGTGATCAAAACAAAAATTGCATATTTATTGCATTCAAAGGGACATTTTGTAGTCTAACCTGATTTTCGAAATTGATTATTGATAATTTAAGATATTTTTCATAGTTATATGAGTTACCTTTAGTAATGATAGACAATAAATAAAGAACTAAGAAGTTGTCAtgaaagtcatagccagagcaggtagataagagaaagaaataaagggcatccaaactagaatggagaagtcaaattgttctctatgcagatgacatgatgttatatatataaaaacaaaactaaagactctaccaaaaaactcatagaactgataaatttagaaaagttagaagatacaaaattagtatacaaaaatcagtagcatttctatgcatgaacagtgaactagctgaaaaagaaatcaaggtaaccccatttataatagctgtgaaaaaaatctaggaataaattaaccaagaaggtaaaatatttctatacaaggaaaactacaaaacactgatgaaagaaattgaaggagatacaaacaaattgaaagacactccgtactcatggattagaggaattaatatattttaaatgaccatgctacccaaagtgatctccagattcaatacaacttctatcaaaataactgacattcttcacagaaattgccaccaaaaaaaattcttaaaatttatatggaaccacaagaccccaaatagccaaagcaatactgagcaaaaagaacaaagctggagttatcacactaccagatctcaaaatataaatcaaaaatgtagtaaccaaaacagcctgatactggcataaaaatagatacagagcaatggaacagaacagagaaccagaaattaatccacgtatctacagccaactgattttttacaaaggtggcaagaatactcattggagggacaaaaaaaaaagggacagtctcttcaataaatggtgctgagaaaactgggtatccatatgcagaagaatgaaactagatccgcacctcccaccctgtacaaaaaccaactcaaaatggatgaaagacctaaatgtaagacctaaaacaataaaactaccataagagaaaacaagaagcacttcaggacattggtctgggaaaagattttatgactgagacctaaaagcacaggcaacaaaaacatgggatcatatcaaattaaaaagcttctgtgcagcagaggaaaccatcaacagtgaaaagacagcttacagaatgggagaaaatatttgtaaactactcatgcaacagaggattaatattcagaatatagaagatattcaaacatcttaatagcaaaacaaatctagattaaaaatgggcaaatcatctgaacagacatttctcaaaagaagacgtacaaatggccaataaatgtatgaaaaaattctaaacactaagcatcagggtaatgcacatcaaaaccacaatgagTAAGTTGGAAGTTCAGGGAAGAGATTTTATCTCATTTACATATGATTAAAAGTCagacattggcacccccatgtttattgtagcactattcattagccaagacatggaatcaacccagaatcaacaggtgcatcaacaggtgaatggctaaacaagatgtggtattatacacaatgggatactattcagccataaaaaaagaatgtcctttcatttgcagcaacatggaaggaactggaggactttatagtaggtgaaataagccagcaatggaaaattaaacaatgcatgttctcactcatgtggaagttttaaaaagttaatcttatagaagtaaaaattaggacagcgcatactagaggctgagaagatagggggaaggaagggatagggagagatttgtgggaggatgcaaaataacataggaataagccctagtgttgtgtaccactatagcatgactatagttaatatatactttaaaatagaagaatattgaatgttcccaacacaaagaaattataggtgtttgagatgatggatatgcttgttaccctgagctgataactgtacattctttgtatcaaagtattctaccccacgaatatgtagaattattattcgtgaattTGAAGAATTAAGTTTTTTAAAAAGTGTACGggctgggcacagtggctcacacctgtagtcccagcactgaggcaggacgatcccttgaggcctgcagtttgagatcagcctggcaacaaaatgaggacctgtctctacaaaaaaaaaaaatagccaaacatggtggtgtgcatctgtagccctagctactggggagtctgaggcagaaagatcactctagtccagaagttcaatgttatggtgaactgtgaacgcaccactgcactccagcctgagcaacacagcaagaccctccaaaaaaaGTGTAGTTATCGTAACATCACCTTGAAACAACTTTGTTACTGGGATACATTTAATTAAGCAACTACCATGAATGTAGTCGGTACCTTGCCTTACGTGCTTCAGTATATATGTTGTTCTTGTTTTATGTACAGGCTAAATTTGTAGATTGAATAGCAGAATATTAGTTCTGTTCTTATAGGGCCTACTGCTGTATTCAGAGTTATGAGCTACGTTTCTTCTGCGTTTGCTGCACCATGAAATCCTAAGCAAGACCTAAACCCTTGTTCGCTTTTTCGTAGAGCAGAGAGGAGCCTTCAGGGGAAGTAGAGGTGGCCGAGGTTGGGGCACACGAGGAAATCGTAGTCGGGGAAGACTCTACTGAATAAGACATCAGCATTCTTCAGCATTGTCATGAGCTTAATATACTTAAATTCTACTACTCATTGGATTGCCGGGGATGTCCCTTTAAACAGACTGCTGCCTTCAGCTAAAAACTTAATGTTCTTTATACCTTTGTATGTATGACCTACTTTTGTAACAGACCATGGTTGTGTCCAAGGTAAAACCACAGTGATATTTTTGGATGCTTTGTCTGCAATCTTGACTTGTTTTTGCAGTATCATTATTCAGACTTCAAATTGTGAATCTTTTAAACATCTTGATAATTTGTTGTTGAGAGCTGTTCATTCTAAAATGTAATGAAATTCAGTCTAGTTCTGCTGATAAAGATCATCAGTTTTGAAAGGTTACTGATTTTCCTCTTCCCTCTTAGTTTTTTACCCAATATATGGAGAAGAGTAATGGTCAATCTTAACATTTTGTTTTAATTGTTTAATAAAGCTGCTGGGCAGTGGTGCAGCATTCCTACCTAGTGTCATAAAAGCAAAATACTTACATAGCTTTCTTAAAATATAGGAATGACATTACATTTTTAGGAGAAAGTAAGTTGCTTTGCACCGCCTACTTAATTCTTTTCCATATATTGTGATACAAACTTTTGAATATGGAATCTTACtatttgaatagaaatgtgtatgtataatatacatacatacataagcatatatgtgtgtgtgtgtgtgtatatatatatatatGCATGCTGTGAAACTTGACTACACAACATAAATCACTTTTTAAATTCCAGGAACGGGTAGTCTGACACGGTGATTATCCTTTTGAGGCTGAATCCGTTATTAACTTGTTATTTAGGTTTTTACTCCCAGTAGCAAGGGATTCTAAGTTAGTTGCACTTACATGATTATTGTTATTTAAAACTAAGAATAAAGGCTGCATTTTCAAAGATAAATTGGAATTGCTGTTGGTGAAATAACAACCAAAATACTGAATCTGATGTACATACAGGTTTCTACAGGAAGAGATGGTATAATTTACAATTTGGAGATTTAATAACCAGGGCTACCCAGAAAAAGTGACTTGATAACATGGTACCAATAAGTAAGGGATGCTCTCTCGGTTTGCTTTTGCCACTTTCAAGATTTTAACTTCTCAGGTTATTAATCAAAATTATTGTATAAGTTAGCCAATAGAATTTTTAGGTTAAAACAACAGATGGGGGGTTTGTGGAGTGTTTAATGTCATGGGCATTTTTAGTAGGATAGACCCTTTGTTCTGCATTTGAATGTTTCGTATATTTTTGTTTCACAGTTAATCTTCCCTCCCCAAGTTTGCTATTCAAATCAACTGCCTGAATGACATTTCTAGTAGTCTGATGTATTTTTCTGAGGAATAGTTTGTGATTCCAATGCAGGTGTCTTCATTACCATTACCTCTACACTGCAGAAGAAGCAAAACTCCTTTATTAGAATTACTGCACATGTGTATGGGGAAAATAGTTCTGAAAGGCTAGAATGATACAAGTGAGCAAAAGTTGGTCAGCTTGGCTATGGAGTGGTGGCAATAATCTCTAAACATTCCAAAAGACCATGAGCTGAACCTAAACTCCCTTGGAATCTGAACAAAGGAATATAAAATTGCCATTTGAAAACTGACCAGCTAATCTGGACCTCAGAGATAGATCAGCCAGTGGCCCAAAGCCATTTCAAGTACAGAAATTATAGAGACTACAGCTAAATAAATTTGAACATTAAATATAATTTTACCACTTTTTGTCTTTATAAGCATATTTGTAAACTCAGAACTGAGCAGAAGTGACTTTACTTTCTCAAGTTTGATACTGAGTTGACTGttcccttatccctcacccttccccttccctttccTAAGGCAATAGTGCACAACTTAGGTTATTTTTGCTTCCGAATTTGAATGAAAAACTTAATGCCATGGATTTTTTTCTTTTGCAAGACACCTGTTTATCATCTTGTTTAAATGTAAATGTCCCCTTATGCTTTTGAAATAAATTTCCTTTTGTAATTTTG 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