Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name API5P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:116104365-116108497  UCSC
Coordinates (T2T) chrX:114513938-114518074  UCSC
Coordinates (hg19) chrX:115235618-115239750  UCSC
Strand -
Parental Sequence XM_006718359.4
Parental seq. overlap 2239 bp
Parental seq. overlap (%) 27.3%
Genomic Region Intergenic
Retrocopy Summary API5P1, located on chrX:116104365-116108497, is a retrocopy of the parental gene API5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name API5
Full Name apoptosis inhibitor 5
Also known as AAC-11|AAC11
Coordinate chr11:43311970-43344530
Strand +
Gene summary This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes API5P2
Bonobo Pan paniscus API5P2
Gorilla Gorilla gorilla API5P2
Orangutan Pongo abelii API5P2
Velvety free-tailed bat Molossus molossus API5P2
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>API5P1
GCTATGAAACTTGACTACACAACATAAATCACTTTTTAAATTCCAGGAACGGGTAATCTGACACAGTGATTATCCTTTTGAGGCTGAATCTGTTATTAACTTGTTATTTAGGTTTTTACTCCCAGTAGGAAGGGATTCTAAGTCAGTTGCACTTACATGATTATTGTTATTTAAAACTAAAAATAAAGGATGCATTTTCAAAGATAAATTGGAGTTGCTATTGGTGAAATACAACCAAAATACTGAATCTGATGTACATATAGGTTTCTACAGGAAGAGATATTATAATTTAGAATTTGGAATTTAATAACCAGGGCTACCCAGAAAAAGTGACTTGATAACATGGTACCAATAAGTAAGGGATGCTCTCTCTGTTTGCTTTTGCCACTTTCAAGATTTTAACTTCTCAGGTTATTAATCAAAATTATTGTATAAGTTAGCCAATAGAATTTTTAGGTTAAAACAACAGATGGGGGGTTTTTGGAGTGTTTAATGTCATGGGCATTTTTAGTAGCATAGACCCTTTGTTCTGCATTTGAATGTTTCGTATATTTTTGTTTCACAGTTAATCTTTCCTCCCCAAGTTTGCTATTCAAATCAACTGCCTGAATGACATTTCTAGTAGTCTGATGAATTTTTTTGAGGAATAGTTTGTGATTCCAATGCAGGTGTCTTCATTACCATTACCTCTACACTGCAGAAGAAGCAAAACTCCTTTATTAGAATTACTGCACATGTGTATGGGGAAAATATTTCTGAAAGGCTAGAATGATACAAGTGAGCAAAAGTTGGTCAGCTTGGCTATGGAGTGGTGGTAATAATCTCTAAACATTCCAAAAGACCATGAGCTGAGCCTAAACTCCCTTGGAATCTGAACAAAGGAATATAAAATTGCCATTTGAAAACTGACCAGGTAATCTGGACCTCAGAGATAGATCAGCCAGTGGCCCAAAGCCATTTCAAGTACAGAAATTGTATTGAGAATACAGCTAAATAAATTTGAAGATTAAGTATAATTTTACCACTTTTCCTCTTTATAAGCACATTTGTAAACTCAAAACTGAGCAGAAGTGACTTTACTTTTCTCAAGTTTGATACTGAGTTGACTGTTCACTTATCCCTCACCCTTCCCCTTCCCTTTCCTAAGGCAATAGTGCACAACTTAGGTTATTTTTGCTTCCGAATTTGAATGAAAAACTTAATGCCATGGATTTTTTTTCTTTTGCAAGACACCTGTTTATCACCTTGTTTAAATGTAAATGTCCCCTTATTCTTTTGAAATAAATTTCCTTTTGTAATTTATCCGAGGCGGCAGTGGCGCCGGTGAGGACAAGGATAGCGGAAGCGGGCCCTGGGCTTGTCACTCACTGTGCCGAACGTAGAGGAGCTTTACCGCAATTATGGCATCCTGGCCGATGCCATGGAGCAAGTGGTCCAGCATAAAAATGCCTATGAAGTGATACCGGGTGGTGTGAAAGGTGGTACTAAGGAAAAACGATTAGTAGCCCAATTTATTCCGAAATTCTTTAAGCAGTTTCCAGAATTGGTTGAGTCTGCTATCAATGCACTGTTAGACCTCTGTGAGGATGAAGATGTATCTATTCGACGTCAAGCAATTAAAGAACTGCCTCAATTTGCCACTGGAGAAAATCTTCCTCGAGTGGCAGATATATTAATGCAACTTTTGCAGACAAATAACTCTGCAGAATTTAACCTAGTGAACAACGCCCTGTTAAGTATATTTAAAATGGTTGCAAAAGGGACTTTAGGTGGGTTGTTCAGCCAAATACTTCGAGGAGAGGACATTGTTAGAGAACGAGCAATTAAATTCCTTTCTACAAAACTTAAGACTTTACCAGATGAAGTCTTAACAAAGGAAGTGAAAGAGCTTATACTAACTGAATCCAAAATGTCCTAGAAGATGTGACTGGTGAAGAATTTGTTCTATTATGAAGATACTGTCTGGGCTAAAAAGCTTACAGTGAGTGGAAGATAGCAACTTGTAGGGTTGGTGGCTGAACAGGCCGACCTAGAACAGACCTTCAATCCCTCGGATCTTGACTGTGTGTACAGGCTCTTACAGTGCACTCGGCAAGCAGTACCCCTCTTCTCTAGAATTATCCATTCCACAAGGTTTGTGACATATTTCTGTGAGCAGGTTCTCCCTAACCTCAGTACCTTGACTACCCCAGTGGAAGGTCTTGATATACAGTTGGAGGTATTGAAATTGTTGGCTGAGATGAGTTCATTTTGTGGTGACATGGAAAAACTAGAAACAAATTTAAGAAAACTATTTGATAAGTTATAGGAATACATGCCGCTCCCTCCAGAAGAAGCAGAAAATGGAGAGAATGCTGGTAATGAAGAACCCAAGCTACAGTTCAGTTATGTGGAATGTTTGTTGTATAGTTTTCACTAGTTGGGCCGAAAACATCCAGATTTCTTAACAGCCAAACTGAATGCAGAAAAGCTCAAAGATTTCAAAATCAGGCTGCAGTACTTTGCACGGGGCCTGCAAATTTATATCAGACAACTTCGCTTAGCTCTCCAGGGTAAAAGCTCTCCAGGGTGAGGCCTTAAAAACAGAAGAGAACAAGATTAAAGTCGTTGCATTGAAAATAACAAACAATATCAATGCTTTAATCAAGGATCTCTTCCACATTCCTCCTTCTTATAAGAGCACAGTAACACTATCCTGGAAACCTGTACAAAAGGTTGAGATTGGGCAAAAGAGAGCCAGTGAAGATACAACTTCAGGTTCACCACCCAAGAAATCTTCAGCAGGACCAAAAAGAGATGCCAGGCAGATTTATAACCCTCCCAGTGGGAAATATAGCAGCAATTTGAGCAACTTTAATTATGAGAGGAGCCTTCAGGGGAAGTAGAGGTGGCCGAGGTTGGGGCACACGAGGAAATCGTAGTCGGGGAAGACTCTACTGAATAAGACGTCAGCATTCTTCAGCATTGTCGTGGGCTTAATATACATAAATTCTACTAATCATTGAATTGCCGGGGATGTCCCTTTAAACAGACTGCTGCCTTCAGCTAAAAACTTAATGTTCTTTATACCTTTGTATGTATGATCTACTTTTGTAACAGACCATGGTTGTGTCCAAGGTAAAACCACAGTGATATTTTTGGATGCTTTGTCTGCAATCTTGTCTTGTTTTTGCAATATCGTTATTCAGACTTCAAATTGTGAATCTTTTACTTTTAAACATCTTGATAATTTGTTGTTGAGAGCTGTTCATTCTAAAATGTAATGAAATTCAGTCTAGTTCTGCTGATAAAGATCATCAGTTTTGAAAGGTTACTGATTTTCCTCTACCCTCTTAGTTTTTTGCCCAATATATGGAGAAGAGTAATGGTCAATCTTAACATTTTGTTTTAATTGTTTAATAAAGCTGCTGGGCAGTGGTGCAGCATTCCTACCTAGTGTCATAAAAGCAAAATACTTACATAGCTTCCTTAAAATATAGGAATGACATTACATTTTTAGGAGAAAGTAAGTTGCTTTGCACGGCTTACTAAATTCCTTTCCATATATTGTGATACAAACTTTTGAATATGGAATCTTACTATTTGAa
>XM_006718359.4
GCAGCCGCGCTGTGCGCGGTGACTGGCGGCTGCACTGGCGGCAGCTGGAGGTGTAATAGTGCGGGTAGTGGGTTTGGAGAAGTTCCGAGGCGGCGGTGGCGCCGGTCAGGACAAGGATAGCGGAACCGGGCCCTGGGCTTGTCGCTCACCATGCCGACAGTAGAGGAGCTTTACCGCAATTATGGCATCCTGGCCGATGCCACGGAGCAAGTGGGCCAGCATAAAGATGCCTATCAAGTGATATTGGATGGTGTGAAAGGTGGTACTAAGGAAAAGCGATTAGCAGCTCAATTTATTCCGAAATTCTTTAAGCATTTTCCAGAATTGGCTGATTCTGCTATCAATGCACAGTTAGACCTCTGTGAGGATGAAGATGTATCTATTCGACGTCAAGCAATTAAAGAACTGCCTCAATTTGCCACTGGAGAAAATCTTCCTCGAGTGGCAGATATACTAACGCAACTTTTGCAGACAGATGACTCTGCAGAATTTAACCTAGTGAACAATGCCCTATTAAGTATATTTAAAATGGATGCAAAAGGGACTTTAGGTGGGTTGTTCAGCCAAATACTTCAAGGAGAGGACATTGTTAGAGAACGAGCAATTAAATTCCTTTCTACAAAACTTAAGACTTTACCAGATGAAGTCTTAACAAAGGAAGTGGAAGAGCTTATACTAACTGAATCCAAAAAGGTCCTAGAAGATGTGACTGGTGAAGAATTTGTTCTATTTATGAAGATACTGTCTGGGTTAAAAAGCTTACAGACAGTGAGTGGAAGACAGCAACTTGTAGAGTTGGTGGCTGAACAGGCCGACCTAGAACAGACCTTCAATCCCTCGGATCCTGACTGTGTGGACAGGCTCTTACAGTGCACTCGGCAGGCAGTACCCCTCTTCTCTAAAAATGTCCATTCCACAAGGTTTGTGACATATTTCTGTGAGCAGGTTCTCCCTAACCTCGGTACCTTGACTACCCCAGTGGAAGGTCTTGATATACAGTTGGAGGTATTGAAATTGTTGGCGGAGATGAGTTCATTTTGTGGTGACATGGAAAAACTAGAAACAAATTTAAGGAAACTATTTGATAAGTTATTGGAATACATGCCCCTCCCTCCAGAAGAGGCAGAAAATGGAGAGAATGCTGGTAATGAAGAACCCAAGCTACAGTTCAGTTATGTGGAATGTTTGTTGTACAGTTTTCACCAGTTGGGCCGAAAACTTCCAGATTTCTTAACAGCCAAACTGAATGCAGAAAAGCTCAAAGATTTCAAAATCAGGCTGCAGTACTTTGCACGGGGCCTGCAAGTTTATATCAGACAACTTCGCTTAGCTCTCCAGGGTAAAACGGGTGAGGCCTTAAAAACAGAAGAGAACAAGATTAAAGTCGTTGCATTGAAAATAACAAACAATATCAATGTTTTAATCAAGGATCTCTTCCACATTCCTCCTTCTTATAAGAGCACAGTAACACTATCCTGGAAACCTGTACAAAAGGTTGAGATTGGGCAAAAGAGAGCCAGTGAAGATACAACTTCAGGTTCACCACCCAAGAAATCTTCAGCAGGACCAAAAAGAGATGCCAGGCAGATTTATAACCCTCCCAGTGGGAAATATAGCAGCAATTTGGGCAACTTTAATTATGAAAGGGGGGTCAAAAAAGACATCAAGACATCACCCTAGTAAGACATAATGGCAAAAAAATTGATTGCAAAATTGACTGAAAAGGTATTTTTCAAGCCTCCAAGATTGTGGATCAAAAACAGCAAAACCAAGCTCTCTCTATTGTTGCTAACAAGATTGCTATAATGAGGAAGTTTAGAAGTTAATGAAGAGATTTGATCTCATTTACATATGATTAAAAGTCCAGCCTTGTGATAACTTCGATCAGTTTTCTTCATGGGACGACACCTTTGAGGACCATTTCTCTGTGGCTATAAAAGTGACTGACCAATGGATGAGAGACTCTTGTTCTGTACATCACAAGTGACTTGATTTTTCAGCAAAAGATATGCTTAGTTTATATCAGTAGCTGAAACACACTCAGACGCACATACACACATAGCACCTATTTGGCAGTATTCTGAGAAGCTTATGTAGCTGATAAAGCAGTGAAAAAAACTCAGCCTTTAGATCTACATTTGTGTGAGTCCAGTTGCGTGAAATACTGTGATCAAAACAAAAATTGCATATTTATTGCATTCAAAGGGACATTTTGTAGTCTAACCTGATTTTCGAAATTGATTATTGATAATTTAAGATATTTTTCATAGTTATATGAGTTACCTTTAGTAATGATAGACAATAAATAAAGAACTAAGAAGTTGTCAtgaaagtcatagccagagcaggtagataagagaaagaaataaagggcatccaaactagaatggagaagtcaaattgttctctatgcagatgacatgatgttatatatataaaaacaaaactaaagactctaccaaaaaactcatagaactgataaatttagaaaagttagaagatacaaaattagtatacaaaaatcagtagcatttctatgcatgaacagtgaactagctgaaaaagaaatcaaggtaaccccatttataatagctgtgaaaaaaatctaggaataaattaaccaagaaggtaaaatatttctatacaaggaaaactacaaaacactgatgaaagaaattgaaggagatacaaacaaattgaaagacactccgtactcatggattagaggaattaatatattttaaatgaccatgctacccaaagtgatctccagattcaatacaacttctatcaaaataactgacattcttcacagaaattgccaccaaaaaaaattcttaaaatttatatggaaccacaagaccccaaatagccaaagcaatactgagcaaaaagaacaaagctggagttatcacactaccagatctcaaaatataaatcaaaaatgtagtaaccaaaacagcctgatactggcataaaaatagatacagagcaatggaacagaacagagaaccagaaattaatccacgtatctacagccaactgattttttacaaaggtggcaagaatactcattggagggacaaaaaaaaaagggacagtctcttcaataaatggtgctgagaaaactgggtatccatatgcagaagaatgaaactagatccgcacctcccaccctgtacaaaaaccaactcaaaatggatgaaagacctaaatgtaagacctaaaacaataaaactaccataagagaaaacaagaagcacttcaggacattggtctgggaaaagattttatgactgagacctaaaagcacaggcaacaaaaacatgggatcatatcaaattaaaaagcttctgtgcagcagaggaaaccatcaacagtgaaaagacagcttacagaatgggagaaaatatttgtaaactactcatgcaacagaggattaatattcagaatatagaagatattcaaacatcttaatagcaaaacaaatctagattaaaaatgggcaaatcatctgaacagacatttctcaaaagaagacgtacaaatggccaataaatgtatgaaaaaattctaaacactaagcatcagggtaatgcacatcaaaaccacaatgagTAAGTTGGAAGTTCAGGGAAGAGATTTTATCTCATTTACATATGATTAAAAGTCagacattggcacccccatgtttattgtagcactattcattagccaagacatggaatcaacccagaatcaacaggtgcatcaacaggtgaatggctaaacaagatgtggtattatacacaatgggatactattcagccataaaaaaagaatgtcctttcatttgcagcaacatggaaggaactggaggactttatagtaggtgaaataagccagcaatggaaaattaaacaatgcatgttctcactcatgtggaagttttaaaaagttaatcttatagaagtaaaaattaggacagcgcatactagaggctgagaagatagggggaaggaagggatagggagagatttgtgggaggatgcaaaataacataggaataagccctagtgttgtgtaccactatagcatgactatagttaatatatactttaaaatagaagaatattgaatgttcccaacacaaagaaattataggtgtttgagatgatggatatgcttgttaccctgagctgataactgtacattctttgtatcaaagtattctaccccacgaatatgtagaattattattcgtgaattTGAAGAATTAAGTTTTTTAAAAAGTGTACGggctgggcacagtggctcacacctgtagtcccagcactgaggcaggacgatcccttgaggcctgcagtttgagatcagcctggcaacaaaatgaggacctgtctctacaaaaaaaaaaaatagccaaacatggtggtgtgcatctgtagccctagctactggggagtctgaggcagaaagatcactctagtccagaagttcaatgttatggtgaactgtgaacgcaccactgcactccagcctgagcaacacagcaagaccctccaaaaaaaGTGTAGTTATCGTAACATCACCTTGAAACAACTTTGTTACTGGGATACATTTAATTAAGCAACTACCATGAATGTAGTCGGTACCTTGCCTTACGTGCTTCAGTATATATGTTGTTCTTGTTTTATGTACAGGCTAAATTTGTAGATTGAATAGCAGAATATTAGTTCTGTTCTTATAGGGCCTACTGCTGTATTCAGAGTTATGAGCTACGTTTCTTCTGCGTTTGCTGCACCATGAAATCCTAAGCAAGACCTAAACCCTTGTTCGCTTTTTCGTAGAGCAGAGAGGAGCCTTCAGGGGAAGTAGAGGTGGCCGAGGTTGGGGCACACGAGGAAATCGTAGTCGGGGAAGACTCTACTGAATAAGACATCAGCATTCTTCAGCATTGTCATGAGCTTAATATACTTAAATTCTACTACTCATTGGATTGCCGGGGATGTCCCTTTAAACAGACTGCTGCCTTCAGCTAAAAACTTAATGTTCTTTATACCTTTGTATGTATGACCTACTTTTGTAACAGACCATGGTTGTGTCCAAGGTAAAACCACAGTGATATTTTTGGATGCTTTGTCTGCAATCTTGACTTGTTTTTGCAGTATCATTATTCAGACTTCAAATTGTGAATCTTTTAAACATCTTGATAATTTGTTGTTGAGAGCTGTTCATTCTAAAATGTAATGAAATTCAGTCTAGTTCTGCTGATAAAGATCATCAGTTTTGAAAGGTTACTGATTTTCCTCTTCCCTCTTAGTTTTTTACCCAATATATGGAGAAGAGTAATGGTCAATCTTAACATTTTGTTTTAATTGTTTAATAAAGCTGCTGGGCAGTGGTGCAGCATTCCTACCTAGTGTCATAAAAGCAAAATACTTACATAGCTTTCTTAAAATATAGGAATGACATTACATTTTTAGGAGAAAGTAAGTTGCTTTGCACCGCCTACTTAATTCTTTTCCATATATTGTGATACAAACTTTTGAATATGGAATCTTACtatttgaatagaaatgtgtatgtataatatacatacatacataagcatatatgtgtgtgtgtgtgtgtatatatatatatatGCATGCTGTGAAACTTGACTACACAACATAAATCACTTTTTAAATTCCAGGAACGGGTAGTCTGACACGGTGATTATCCTTTTGAGGCTGAATCCGTTATTAACTTGTTATTTAGGTTTTTACTCCCAGTAGCAAGGGATTCTAAGTTAGTTGCACTTACATGATTATTGTTATTTAAAACTAAGAATAAAGGCTGCATTTTCAAAGATAAATTGGAATTGCTGTTGGTGAAATAACAACCAAAATACTGAATCTGATGTACATACAGGTTTCTACAGGAAGAGATGGTATAATTTACAATTTGGAGATTTAATAACCAGGGCTACCCAGAAAAAGTGACTTGATAACATGGTACCAATAAGTAAGGGATGCTCTCTCGGTTTGCTTTTGCCACTTTCAAGATTTTAACTTCTCAGGTTATTAATCAAAATTATTGTATAAGTTAGCCAATAGAATTTTTAGGTTAAAACAACAGATGGGGGGTTTGTGGAGTGTTTAATGTCATGGGCATTTTTAGTAGGATAGACCCTTTGTTCTGCATTTGAATGTTTCGTATATTTTTGTTTCACAGTTAATCTTCCCTCCCCAAGTTTGCTATTCAAATCAACTGCCTGAATGACATTTCTAGTAGTCTGATGTATTTTTCTGAGGAATAGTTTGTGATTCCAATGCAGGTGTCTTCATTACCATTACCTCTACACTGCAGAAGAAGCAAAACTCCTTTATTAGAATTACTGCACATGTGTATGGGGAAAATAGTTCTGAAAGGCTAGAATGATACAAGTGAGCAAAAGTTGGTCAGCTTGGCTATGGAGTGGTGGCAATAATCTCTAAACATTCCAAAAGACCATGAGCTGAACCTAAACTCCCTTGGAATCTGAACAAAGGAATATAAAATTGCCATTTGAAAACTGACCAGCTAATCTGGACCTCAGAGATAGATCAGCCAGTGGCCCAAAGCCATTTCAAGTACAGAAATTATAGAGACTACAGCTAAATAAATTTGAACATTAAATATAATTTTACCACTTTTTGTCTTTATAAGCATATTTGTAAACTCAGAACTGAGCAGAAGTGACTTTACTTTCTCAAGTTTGATACTGAGTTGACTGttcccttatccctcacccttccccttccctttccTAAGGCAATAGTGCACAACTTAGGTTATTTTTGCTTCCGAATTTGAATGAAAAACTTAATGCCATGGATTTTTTTCTTTTGCAAGACACCTGTTTATCATCTTGTTTAAATGTAAATGTCCCCTTATGCTTTTGAAATAAATTTCCTTTTGTAATTTTG

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