Summary

Gene Name	DENR
Specie	Homo sapiens
Full Name	density regulated re-initiation and release factor
Also known as	DRP|DRP1|SMAP-3
Coordinate	chr12:122752824-122771064
Strand	+
Gene summary	This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]

Retrocopy(s) from DENR

Retroname	Coord	Strand	Genomic Region	ENSG
DENRP2	chr12:76057439-76059684	+	Intragenic	ENSG00000257941	UCSC
DENRP3	chr17:63331884-63332571	-	Intragenic	ENSG00000271919	UCSC
DENRP4	chr20:34243568-34246537	-	Intragenic Intragenic Intragenic	ENSG00000236456	UCSC
DENRP1	chr9:127300015-127300996	-	Intragenic	ENSG00000229369	UCSC

Expression

Transcript Sequences

>NM_003677.5

GTCTCGCGGGAGCGCTGCTGGCGGTCGGGCGCTCGGGCGGCCCTGGCCGGGGAGACGAGTTGCATGTGTTGGTTCAGCTGGCGATAGCGGCGGGAGCGGAGCCGGCGGGGCCTGTGCGACCGCCTGGGTTTGTGAAATGGCTGCTGACATTTCTGAATCCAGCGGGGCTGACTGCAAAGGAGACCCAAGGAACAGTGCCAAGTTAGATGCCGATTACCCACTTCGAGTCCTTTATTGTGGAGTCTGTTCATTACCAACAGAGTACTGTGAATATATGCCTGATGTTGCTAAATGTAGACAATGGTTAGAGAAGAATTTTCCAAATGAATTTGCAAAACTTACTGTAGAAAATTCACCCAAACAAGAAGCTGGAATTAGTGAGGGTCAAGGAACAGCAGGGGAAGAAGAGGAGAAGAAAAAACAGAAGAGAGGTGGAAGGGGTCAAATAAAACAAAAAAAGAAGACCGTACCACAAAAGGTTACTATAGCCAAAATTCCCAGAGCAAAGAAGAAATATGTGACAAGAGTATGTGGCCTTGCAACTTTTGAAATTGATCTTAAAGAAGCACAAAGATTTTTTGCTCAAAAATTCTCCTGTGGTGCCTCAGTAACAGGGGAGGATGAAATTATCATTCAGGGAGATTTTACAGATGACATAATTGATGTCATTCAGGAAAAATGGCCAGAGGTAGATGATGACAGCATCGAAGATCTTGGAGAAGTAAAGAAGTGAATTTGAAAATTTGTCTGTATTTAATGGCCTGAACTGAGAGTTGATATGGCCAAAGGGAGAGAGGCCTTTTAAAatatatatatatatacacatatatatgtatatatacacatatatgtatgtatacacatatacacatgtatatatacatgtgtgtatgtatacatgtatatatatatacatacacatatatgtatacatatatacacatatatgtatacatatatacacatatgtatacatatatatatatTCTACAGTAAAACTGTAGACTGTCCTCGTCCTTGGCATTTTCACTGTTCTGTACAAGGCTGCTTGTTTTTTTATTGCCAAAGTCAAATAAACGGGAGACTGTCATGCTCATGCATGAATAGAATTTAGTCAAATAAAAAATTTTGGTCATTTGGTACTGActttctctctctctctctctctcttttttttttttgacagagtctcgcactgttgcctgggctggaatgcagtggtgcgatctcggctcactgcaacctccgcctcccgggttcaagtgattctcctgcctcagcctcccaagtaggtgggattacaggcgcccgccaccacgcccagctaatttttgtatttttagtagagatggggtttcactatgttggccaggctggtctcgaactcctgacctcgtgattggcccacctcagcctcccaaagtgctggtattacagatgtgagccaccgcacccagcctgagtttctctttctctctTTTTAACTTTATTTTTTGAAAAACCCGGTAGACTTTTTGTGGGGAGCATTTTTGTTGATAATTTTACTGATCTAAAGCTGAGTGATTTTTTAAAAGAATTTGAATTTGGCTTCCTCACCAGTAATATGTCTCCTTGCTTCTTTGATGTGATAGTTTTGAGATGGGTGAGAATCTAATAGATCTGTGGTTGAATTTGCTGTGTTGTTATGAAGTCCACCCTGTGGGCACAATAAcataactgttggtaggagttgtttgagctattctggagattatttggtaaagtatactaaaagccttaaaaccatgtatgtgcgctgtttgaacccgtaagccacttctttgacattagaagacattagaagaaataatcagccttgcataaaacttatggatgaaagtattcatcacaatattatttataataaaaaattgcaaatgttataaatgaacaattgggaaatggttaaagaagtgatggtgcattgtgtggtagaatattatgcatatgtttaaagaatcatattttctaagattatttggaagcatgtttggtaatgtcaagtggaGTACCCCAGATACATTTTAGACATTTATCGTCATCATCTGCTCTGAGTGGAAGGCCGTTCAGAGAGGCTAGAGGTTCTTATTCTGGCTATAAATTATGTGAGTAAAATTGTGCTAACCAGTTAAAAGTACTGTACACCCATGCTCAATATATAGTCCTGGAAATAGCAATTGAAACATGTCTTCTCACAAGAGAAAATGACAGTTTTAATGATGTATTTGATGAATTTAAACTTTAAGTCAGGTGCTGCAAATTGGAAAGAAGACTTGTGGTGTTTTAAGTTGCTGTGGACACTTTTAAGAAACTTAGAACCCATGGAACCCTTGTTTATCGCCATGCAAATTACAATCTTGAATGAGTGTTTTTTAAAAATAAAGTATTAGAAAAATGTGTAGTAAAGATGTAAAATTAAAAAATGGAATTCTCCATTAACTGTGGATTTTACTAAATAGAATTACTGGTGAAGCAGATTTATCCATCGAGACTATCTGGTATGCGTTATGTATGTAGTCTGTTGCTGCTGAAAGATGTCTGTGTGCCTGTATCAACATGTGACTTCATGTAAAGTTTCTTTGTGTTCACAGTTCTTAGCAAATGCAGTTACAATCCATAGATAGCCAGCAGTGGATGTTACTCCAGGAAAATGCAGGATTAAAATTGTCCTTGTGTATAA