| Gene Name | COX7A2L |
|
| Specie | Homo sapiens | |
| Full Name | cytochrome c oxidase subunit 7A2 like | |
| Also known as | COX7AR|COX7RP|EB1|SCAF1|SCAFI|SIG81 | |
| Coordinate | chr2:42335559-42368957 | |
| Strand | - | |
| Gene summary | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| COX7A2LP2 | chr11:113769599-113770004 | + |
Intragenic |
ENSG00000257070 | UCSC |
| COX7A2LP1 | chr5:154994177-154995500 | + |
Intergenic |
ENSG00000253261 | UCSC |
| >NM_001319036.1 |
| GGGGAAAGCAGCCAGGGAGGTCGGGAGATGGACGGAAACTGCTGGGGATGTGAGAAGCCTGGGGCACTAACTGGAGTTGTTATTGACTTGGTTGCCAGGGGAAGCTTGGCCGACAAGTCTATACTCCTGGGCAGACTGAGCAACAGCAGGTGGTGGCTTCTGGATAAGAGGTGCTCTAGGTCGGAAGGAAATAAATGAGACTACGATCAGTTAAAGTTCGGTAAAGCAAGAGACGCCTTCAACCCGACGACCAGACGGTGGCTCCGCAGCACAGACTCTCTCGGATGGTGGAATTCCCAACCGGCTTCGATGTAGCCCCGCCCCTACCCAGACCACGCCCACCAATCACCGCCCTCTCCCCCCCAGGCCCCGCCTGGAGCCCGCCCCTCCTAAAGCATGCTCCACCTGACTCCGACACTGCCGGGCTTAGTCCGCCGGGCTTAGTCCGTGGAGCGCTTGCGCATTTCTTGAGTTGTCGTGGCACTGCCCAAATCTGAATGGGGGAAAGAGGGAACTTCATATTTCCTACAGACTCCGCCACAGCGACTTTGCGTGCTCTCTTAGAGCTGGTTTTGCCTTTCGTGGTCCTGAGAACCCTGGCTTTTGGTTCCCCAATGCGGCTTAAGTGTGCAGGTTTTAAGTTAGGCGATCTTCGGGCAGCCCTAGTCCCAGCACCGGGTCCTTGCGCTGAGTCTCGGGACCACAGCCGGGGAGGCGGGGTCCTTCTCTGGGGCGGTCGCGTTGGCAGCGGATGCGGGAAGCCGGACTCTGGGCGTCATGTACTACAAGTTTAGTGGCTTCACGCAGAAGTTGGCAGGAGCATGGGCTTCGGAGGCCTATAGCCCGCAGGGATTAAAGCCTGTGGTTTCCACAGAAGCACCACCTATCATATTTGCCACACCAACTAAACTGACCTCCGATTCCACAGTGTATGATTATGCTGGGAAAAACAAAGTTCCAGAGCTACAAAAGTTTTTCCAGAAAGCTGATGGTGTGCCCGTCTACCTGAAACGAGGCCTGCCTGACCAAATGCTTTACCGGACCACCATGGCGCTGACTGTGGGAGGGACCATCTACTGCCTGATCGCCCTCTACATGGCTTCGCAGCCCAAAAACAAATGAGTTAGGCTGCAGAGGACTGGTTTGTTTTTTGGCATAAACCCTTTGAAGTTCCTTTTTCATTGTTAAATTAAAATTTTTTTTTTTACTTGGATGGCTTAACATTTTTGCAAGAAAAATAGGAAGATATGAAGATGATGTTTTGGTTTGTTTATGAAATGCATATGGCTTGTCAGAGCTCATTCGACAGTTAAAGCCATTGTTTAAAGAAATGGTGCTTTGCTCTGTGTTTGTGCTCCTGATTTCCCTGGAGGTTCTGGATGAAGGCTGAACACAGGCTTGTTAATGTCAGTCTGTGCTGAGGACCTCAGGGACTTGAGGTTGCATTTTTGAGCATGGGGTGCAGGAGCCTTTCTGGATTTGGATGTGGCTATGGAAAGAACACAGAAGCCAAGGTCATGTGCATGAAATGAGGAGTTTGAGTTAGTCACCTCGGGGATTTTTTCCATTTTGCAGTAAAATGTTAAATTAATGTAGCCTGCCTCTATTTGTTGGGCAGGTAATTTCAAAGGGTTATTTGCCTCATCTCCTATCTTTAGTGAAATCTTATGTGTAATTATTCCACCGTGGGAACAGAGAATACCTGTTTAGTGTTGCACTTTAGACTGGTGTCTGTTTTGTTAATGCAGCTGTGCCACAAATTCTCCTTTATCTTTTAAAAATGTTATAGCTTTAAATTTTGATTTATTTTGACTGTGGAATAAATACATGAATGAAAAATTTTAA |