Summary

Gene Name	AIMP1
Specie	Homo sapiens
Full Name	aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Also known as	EMAP2|EMAPII|HLD3|SCYE1|p43
Coordinate	chr4:106315544-106349456
Strand	+
Gene summary	The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]

Retrocopy(s) from AIMP1

Retroname	Coord	Strand	Genomic Region	ENSG
AIMP1P2	chr1:172885899-172886258	-	Intergenic	ENSG00000227177	UCSC
AIMP1P1	chr20:14127397-14128338	+	Intragenic	ENSG00000234187	UCSC

Expression

Transcript Sequences

>NM_001142415.2

ACTTTCTCCTACTGCTCAAGGGGGTGTTACACTTTGACGACTGACTAAACCTCGAGGGCCAGAAACAAACCAAAGCAAAATTCTGCCTCCAAGGATTTTCTGCCGTCTCTTGGCAAAAATGGCAAATAATGATGCTGTTCTGAAGAGACTGGAGCAGAAGGGTGCAGAGGCAGATCAAATCATTGAATATCTTAAGCAGCAAGTTTCTCTACTTAAGGAGAAAGCAATTTTGCAGGCAACTTTGAGGGAAGAGAAGAAACTTCGAGTTGAAAATGCTAAACTGAAGAAAGAAATTGAAGAACTGAAACAAGAGCTAATTCAGGCAGAAATTCAAAATGGAGTGAAGCAAATACCATTTCCATCTGGTACTCCACTGCACGCTAATTCTATGGTTTCTGAAAATGTGATACAGTCTACAGCAGTAACAACCGTATCTTCTGGTACCaaagaacagataaaaggaggaacaggagacgaaaagaaagcgaaagagaaaattgaaaagaaagGAGAGAAGAAGGAGAAAAAACAGCAATCAATAGCTGGAAGTGCCGACTCTAAGCCAATAGATGTTTCCCGTCTGGATCTTCGAATTGGTTGCATCATAACTGCTAGAAAACACCCTGATGCAGATTCTTTGTATGTGGAAGAAGTAGATGTCGGAGAAATAGCCCCAAGGACAGTTGTCAGTGGCCTGGTGAATCATGTTCCTCTTGAACAGATGCAAAATCGGATGGTGATTTTACTTTGTAACCTGAAACCTGCAAAGATGAGGGGAGTATTATCTCAAGCAATGGTCATGTGTGCTAGTTCACCAGAGAAAATTGAAATCTTGGCTCCTCCAAATGGGTCTGTTCCTGGAGACAGAATTACTTTTGATGCTTTCCCAGGAGAGCCTGACAAGGAGCTGAATCCTAAGAAGAAGATTTGGGAGCAGATCCAGCCTGATCTTCACACTAATGATGAGTGTGTGGCTACATACAAAGGAGTTCCCTTTGAGGTGAAAGGGAAGGGAGTATGTAGGGCTCAAACCATGAGCAACAGTGGAATCAAATAAAATGCTTCCACTACCAAAAGACATTAGAGAAAACCTTAAAAGTAATAAAGAGAAATATATTTGTCACTTATACCTAAAATATGAGTGGCTCATTTTTGCATTACTCTCTTCTAGACTTGACTAGTCATTTACTTGGTATATATTGTTTTCATTGATTGGGGAAACACTAGATTTTTACCTCGGTTTTTGATCATTTATAATGGAGAGAGGAAGTTGCCTATGTTTTGTAATAATTTATTTTTTAGCAGGAATATTGATTAGCAGCTTTTTTTTCTTTATACACATAGATAACTAACTAGATTAATGTTTAGTTTCTTATTTGTAGGCACAGGATGCATGAAATTTCAAGCTCTGGGATTTTTTGTATATTGTGTATCTGTATCAAAAATATCCTCTCCTTTTCAAAAATGACAGGTTGGAAAATGTTTGTCAGACTTATTAACTGGTCATATTATAATAATACTGATAATGACCAACTGCTCATTCTGAAAGCCAAACATAAAAGCTAGGAGAAGTGGCATCTGAACATTTTTGCTTTGCTGCCAGAGTAACCCTGACTAATAATACAATAACAGCAATTTTTTTAAAAAACTGAGATTTCCTACTGGCTTGAAGTTTTTCTATTTAGCAAAATAATTAGTAATAAGTTTTGACTAGGTCTAAAGAATGAACACATTGTAAACAGTTGCCACAGTAGTTTCTAATAAATTGATCATAAAAGCAGCTATCCTTTTTTTTTTTAATTCTAGCTTCTTTTTAAAGATTATTTGGGTACCTAATAAAGGATAATTTATATCTTATTACAGACTGATATTTTGCTTTTTCATGTGTCATCATACTGTCAGTATATTAAAAGAAATTACAGCCTAAAACTTAACATATACCATACATATATATTAAGGTGTCAAATAGCTATTCTCACTCATCTTACAAATATTGTAAGAGCAATAAAAATTAATTGAGGAATTATAAGCCTACAGGTCATCAGCCTTGAGGTGATTACTGATGATTTGGGCTTACACACATGTCAGCAAGATAGggagtgtggataggggagggctggtagctaacaaggggcctcacagagaaatattagtgactttaaccaggtttcagaatctgggccttacctttacaggttcaACAAAAGAATGGCATCAATAGAGGCAGAAGTATAGACATTGTTTTAAAAATACACACATGCACACACACACAAAACATTTTAGCATTATAGCTGTCTGAATCCTTCAATAAGAAGGAGAGGcacacacaaatacacacactcacacaaaactcaacaaccataaaacaaCCCTGCATGTTATAAAAGGCAGAATTAAATTTTATTTATTTAAATCCATGGAACTCTGGTAGGCCAGGATATATTATAGTACCATTATCAATGTGATATTCTGAAAATATGAACTGAGCGTCATTAACAATTGTTGGTACCTAAACACAAAATGAATTTCAAAAGTTACTTTGTTCTCAAGATATGTCATTCTTTTGGGAATAAATACTTCTGGTGACAAAGTCTTTTGTGAGTTTTTTGCTCTAATTTTTCTCaattatattaaatttctttaatataatttaaataatattTCAACTACCTAGGTAGTTGAAATTTTCCCAACTAAATGTTGAAATACTGTACCCCAGATCAAATTATCTAATGTTTTGTTAGTGAAACCTAAACTGATGATTAAATCGTTCATCAAACCTAGAGATAATAAAAACTATTGGTCTTTTGTTAAAAGCCCA

>NM_001142416.2

GCTTCCTGCTGTGGCTGTCTCGGAACCCGTGGTCCTCCGCTTCATGATTTTCTGCCGTCTCTTGGCAAAAATGGCAAATAATGATGCTGTTCTGAAGAGACTGGAGCAGAAGGGTGCAGAGGCAGATCAAATCATTGAATATCTTAAGCAGCAAGTTTCTCTACTTAAGGAGAAAGCAATTTTGCAGGCAACTTTGAGGGAAGAGAAGAAACTTCGAGTTGAAAATGCTAAACTGAAGAAAGAAATTGAAGAACTGAAACAAGAGCTAATTCAGGCAGAAATTCAAAATGGAGTGAAGCAAATACCATTTCCATCTGGTACTCCACTGCACGCTAATTCTATGGTTTCTGAAAATGTGATACAGTCTACAGCAGTAACAACCGTATCTTCTGGTACCaaagaacagataaaaggaggaacaggagacgaaaagaaagcgaaagagaaaattgaaaagaaagGAGAGAAGAAGGAGAAAAAACAGCAATCAATAGCTGGAAGTGCCGACTCTAAGCCAATAGATGTTTCCCGTCTGGATCTTCGAATTGGTTGCATCATAACTGCTAGAAAACACCCTGATGCAGATTCTTTGTATGTGGAAGAAGTAGATGTCGGAGAAATAGCCCCAAGGACAGTTGTCAGTGGCCTGGTGAATCATGTTCCTCTTGAACAGATGCAAAATCGGATGGTGATTTTACTTTGTAACCTGAAACCTGCAAAGATGAGGGGAGTATTATCTCAAGCAATGGTCATGTGTGCTAGTTCACCAGAGAAAATTGAAATCTTGGCTCCTCCAAATGGGTCTGTTCCTGGAGACAGAATTACTTTTGATGCTTTCCCAGGAGAGCCTGACAAGGAGCTGAATCCTAAGAAGAAGATTTGGGAGCAGATCCAGCCTGATCTTCACACTAATGATGAGTGTGTGGCTACATACAAAGGAGTTCCCTTTGAGGTGAAAGGGAAGGGAGTATGTAGGGCTCAAACCATGAGCAACAGTGGAATCAAATAAAATGCTTCCACTACCAAAAGACATTAGAGAAAACCTTAAAAGTAATAAAGAGAAATATATTTGTCACTTATACCTAAAATATGAGTGGCTCATTTTTGCATTACTCTCTTCTAGACTTGACTAGTCATTTACTTGGTATATATTGTTTTCATTGATTGGGGAAACACTAGATTTTTACCTCGGTTTTTGATCATTTATAATGGAGAGAGGAAGTTGCCTATGTTTTGTAATAATTTATTTTTTAGCAGGAATATTGATTAGCAGCTTTTTTTTCTTTATACACATAGATAACTAACTAGATTAATGTTTAGTTTCTTATTTGTAGGCACAGGATGCATGAAATTTCAAGCTCTGGGATTTTTTGTATATTGTGTATCTGTATCAAAAATATCCTCTCCTTTTCAAAAATGACAGGTTGGAAAATGTTTGTCAGACTTATTAACTGGTCATATTATAATAATACTGATAATGACCAACTGCTCATTCTGAAAGCCAAACATAAAAGCTAGGAGAAGTGGCATCTGAACATTTTTGCTTTGCTGCCAGAGTAACCCTGACTAATAATACAATAACAGCAATTTTTTTAAAAAACTGAGATTTCCTACTGGCTTGAAGTTTTTCTATTTAGCAAAATAATTAGTAATAAGTTTTGACTAGGTCTAAAGAATGAACACATTGTAAACAGTTGCCACAGTAGTTTCTAATAAATTGATCATAAAAGCAGCTATCCTTTTTTTTTTTAATTCTAGCTTCTTTTTAAAGATTATTTGGGTACCTAATAAAGGATAATTTATATCTTATTACAGACTGATATTTTGCTTTTTCATGTGTCATCATACTGTCAGTATATTAAAAGAAATTACAGCCTAAAACTTAACATATACCATACATATATATTAAGGTGTCAAATAGCTATTCTCACTCATCTTACAAATATTGTAAGAGCAATAAAAATTAATTGAGGAATTATAAGCCTACAGGTCATCAGCCTTGAGGTGATTACTGATGATTTGGGCTTACACACATGTCAGCAAGATAGggagtgtggataggggagggctggtagctaacaaggggcctcacagagaaatattagtgactttaaccaggtttcagaatctgggccttacctttacaggttcaACAAAAGAATGGCATCAATAGAGGCAGAAGTATAGACATTGTTTTAAAAATACACACATGCACACACACACAAAACATTTTAGCATTATAGCTGTCTGAATCCTTCAATAAGAAGGAGAGGcacacacaaatacacacactcacacaaaactcaacaaccataaaacaaCCCTGCATGTTATAAAAGGCAGAATTAAATTTTATTTATTTAAATCCATGGAACTCTGGTAGGCCAGGATATATTATAGTACCATTATCAATGTGATATTCTGAAAATATGAACTGAGCGTCATTAACAATTGTTGGTACCTAAACACAAAATGAATTTCAAAAGTTACTTTGTTCTCAAGATATGTCATTCTTTTGGGAATAAATACTTCTGGTGACAAAGTCTTTTGTGAGTTTTTTGCTCTAATTTTTCTCaattatattaaatttctttaatataatttaaataatattTCAACTACCTAGGTAGTTGAAATTTTCCCAACTAAATGTTGAAATACTGTACCCCAGATCAAATTATCTAATGTTTTGTTAGTGAAACCTAAACTGATGATTAAATCGTTCATCAAACCTAGAGATAATAAAAACTATTGGTCTTTTGTTAAAAGCCCA