Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Gene Name PDLIM7
Plot displaying the genomic locations of a parental gene (in chr5) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name PDZ and LIM domain 7
Also known as LMP1|LMP3
Coordinate chr5:177483394-177497604
Strand -
Gene summary The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Retrocopy(s) from PDLIM7

Retroname Coord Strand Genomic Region ENSG
PDLIM7P1 chr8:28238726-28239060 + Intergenic
ENSG00000253907 UCSC

Expression

Transcript Sequences

>NM_213636.3
GTCAGAACACTGGCGGCCGATCCCAACGAGGCTCCCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCCGGCATCATGGATTCCTTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAAGCGGCGCAGGCCGGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAACAAGATCCGGGCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGgcctCCGCCCCCGCCGCGGACCCTCCGCGGTACACCTTTGCACCCAGCGTCTCCCTCAACAAGACGGCCCGGCCCTTTGGGGCGCCCCCGCCCGCTGACAGCGCCCCGCAGCAGAATGGACAGCCGCTCCGACCGCTGGTCCCAGATGCCAGCAAGCAGCGGCTGATGGAGAACACAGAGGACTGGCGGCCGCGGCCGGGGACAGGCCAGTCGCGTTCCTTCCGCATCCTTGCCCACCTCACAGGCACCGAGTTCATGCAAGACCCGGATGAGGAGCACCTGAAGAAATCAAGGGAAAAGTATGTCCTGGAGCTGCAGAGCCCACGCTACACCCGCCTCCGGGACTGGCACCACCAGCGCTCTGCCCACGTGCTCAACGTGCAGTCGTAGCCCGGCCCTCTCCAGCCGGCTGCCCTCTCTGCCTCCCTCTTTCTGTTCCTCCTGCCCAGGGCACCCCCTTAGTGCCTCCAGCTTCTGCCTACCTCACCCCCCCTTTCGTGCCcctggcctgagcctcctgctggcctggccctggccGCCCACCTGGGTTCATCTGACACTGCCTTCCCTCTTTGCCCTGTGGTACTGCTGTCTGCCAGGTCTGTGCTGCCTTGGGCATGGAATAAACATTCTCAGCCCTG