| Gene Name | ABCG2 |
|
| Specie | Homo sapiens | |
| Full Name | ATP binding cassette subfamily G member 2 (Junior blood group) | |
| Also known as | ABC15|ABCP|BCRP|BCRP1|BMDP|CD338|CDw338|CDw388|EST157481|GOUT1|MRX|MXR|MXR-1|MXR1|UAQTL1 | |
| Coordinate | chr4:88090264-88231626 | |
| Strand | - | |
| Gene summary | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| ABCG2P1 | chr15:69022218-69024220 | + |
Intragenic |
ENSG00000273851 | UCSC |
| >NM_001348985.1 |
| TTACATCAGGGTTAAAAAAGCACAGGAAGTTTACGCACAGAGCAAAGCCATTTGCTAGAATTGGTTTTTATCCTTCCATTTCGAAAATAAAGTTGCTGTTTGTGTTGGAGATGCTGTCATCAGAATTCCGCGGCACAAAGAGAAAGATACAAAAATATCTCTCTGACATGTAACTTTCCCCCTTCTTCTAGCCCCTTGCTAGGAATGCCAGAAGAGGATCCCACGCTGACTGGAACCATTAGGTCTTTTGTTTGAATCCCAGTGATCGAGAAAGAAATGTGGTTCATAATCAGCTAGTAGTGGAGAAAAAAGGAACCCAAGGAGATAGGAGAGCTGTTAATTTCACTCGGGACATTTCCTCGAGGCTAGTTTACTCGGAAAGCCTCAATGTTCCCTGGTAGCTGCAGGATCTACTTTGGGGGCTGCCAAGTTTCCTCTCTCATTCTTTCTCCTGCCCCAAGAGCAGGCAGGAAGGAAAGTTCCTGGACTGATACTCGTCTGTTTAGTAGGCGTGGGTCCTGGTTGAAGTCTGTCTAGGAAAACTCCTAAGTGTAGAAATCTTCTTCGTATTACCACTGTCTCTGCACTGAGATTTGGGCTGCTTTGCTTCCAGCGTCACACATCATAACTGAGTGCAGTACCGGTTTGACTGTATCTTCAAGTTAAGAGAATTGCTGTATTCCCCAAAATATCTTGGTCATTTGAAAGTAAAGAGTTCTCggccgggcacagtggctcacgcctgtaatcccagcacttcagaaggcaaagAAAGATAAAAACTCTCCAGATGTCTTCCAGTAATGTCGAAGTTTTTATCCCAGTGTCACAAGGAAACACCAATGGCTTCCCCGCGACAGCTTCCAATGACCTGAAGGCATTTACTGAAGGAGCTGTGTTAAGTTTTCATAACATCTGCTATCGAGTAAAACTGAAGAGTGGCTTTCTACCTTGTCGAAAACCAGTTGAGAAAGAAATATTATCGAATATCAATGGGATCATGAAACCTGGTCTCAACGCCATCCTGGGACCCACAGGTGGAGGCAAATCTTCGTTATTAGATGTCTTAGCTGCAAGGAAAGATCCAAGTGGATTATCTGGAGATGTTCTGATAAATGGAGCACCGCGACCTGCCAATTTCAAATGTAATTCAGGTTACGTGGTACAAGATGATGTTGTGATGGGCACTCTGACGGTGAGAGAAAACTTACAGTTCTCAGCAGCTCTTCGGCTTGCAACAACTATGACGAATCATGAAAAAAACGAACGGATTAACAGGGTCATTCAAGAGTTAGGTCTGGATAAAGTGGCAGACTCCAAGGTTGGAACTCAGTTTATCCGTGGTGTGTCTGGAGGAGAAAGAAAAAGGACTAGTATAGGAATGGAGCTTATCACTGATCCTTCCATCTTGTTCTTGGATGAGCCTACAACTGGCTTAGACTCAAGCACAGCAAATGCTGTCCTTTTGCTCCTGAAAAGGATGTCTAAGCAGGGACGAACAATCATCTTCTCCATTCATCAGCCTCGATATTCCATCTTCAAGTTGTTTGATAGCCTCACCTTATTGGCCTCAGGAAGACTTATGTTCCACGGGCCTGCTCAGGAGGCCTTGGGATACTTTGAATCAGCTGGTTATCACTGTGAGGCCTATAATAACCCTGCAGACTTCTTCTTGGACATCATTAATGGAGATTCCACTGCTGTGGCATTAAACAGAGAAGAAGACTTTAAAGCCACAGAGATCATAGAGCCTTCCAAGCAGGATAAGCCACTCATAGAAAAATTAGCGGAGATTTATGTCAACTCCTCCTTCTACAAAGAGACAAAAGCTGAATTACATCAACTTTCCGGGGGTGAGAAGAAGAAGAAGATCACAGTCTTCAAGGAGATCAGCTACACCACCTCCTTCTGTCATCAACTCAGATGGGTTTCCAAGCGTTCATTCAAAAACTTGCTGGGTAATCCCCAGGCCTCTATAGCTCAGATCATTGTCACAGTCGTACTGGGACTGGTTATAGGTGCCATTTACTTTGGGCTAAAAAATGATTCTACTGGAATCCAGAACAGAGCTGGGGTTCTCTTCTTCCTGACGACCAACCAGTGTTTCAGCAGTGTTTCAGCCGTGGAACTCTTTGTGGTAGAGAAGAAGCTCTTCATACATGAATACATCAGCGGATACTACAGAGTGTCATCTTATTTCCTTGGAAAACTGTTATCTGATTTATTACCCATGAGGATGTTACCAAGTATTATATTTACCTGTATAGTGTACTTCATGTTAGGATTGAAGCCAAAGGCAGATGCCTTCTTCGTTATGATGTTTACCCTTATGATGGTGGCTTATTCAGCCAGTTCCATGGCACTGGCCATAGCAGCAGGTCAGAGTGTGGTTTCTGTAGCAACACTTCTCATGACCATCTGTTTTGTGTTTATGATGATTTTTTCAGGTCTGTTGGTCAATCTCACAACCATTGCATCTTGGCTGTCATGGCTTCAGTACTTCAGCATTCCACGATATGGATTTACGGCTTTGCAGCATAATGAATTTTTGGGACAAAACTTCTGCCCAGGACTCAATGCAACAGGAAACAATCCTTGTAACTATGCAACATGTACTGGCGAAGAATATTTGGTAAAGCAGGGCATCGATCTCTCACCCTGGGGCTTGTGGAAGAATCACGTGGCCTTGGCTTGTATGATTGTTATTTTCCTCACAATTGCCTACCTGAAATTGTTATTTCTTAAAAAATATTCTTAAATTTCCCCTTAATTCAGTATGATTTATCCTCACATAAAAAAGAAGCACTTTGATTGAAGTATTCAATCAAGTTTTTTTGTTGTTTTCTGTTCCCTTGCCATCACACTGTTGCACAGCAGCAATTGTTTTAAAGAGATACATTTTTAGAAATCACAACAAACTGAATTAAACATGAAAGAACCCAAGACATCATGTATCGCATATTAGTTAATCTCCTCAGACAGTAACCATGGGGAAGAAATCTGGTCTAATTTATTAATCTAAAAAAGGAGAATTGAATTCTGGAAACTCCTgacaagttattactgtctctggcatttgtttcctcatctttaaaatgaataggtaggttagtagcccttcagtcttaatactttatgatgctatggttTGCCATTATTTAATaaatgacaaatgtattaatgctatactggaaatgtaaaattgaaaatATGTTGGAAAAAAGATTCTGTCTTATAGGGTAAAAAAAGCCACCGTGATAGAAAAAAAATCTTTTTGATAAGCACATTAAAGTTAATAGAACTTACTGATATTCCTGTCTAGTGGTATAATATCTCAGGAATCTTGGCTGAGGGTTTGGAACTGTGGGTAGAGTAGAGGGCCAGGAGTCCAGTAATAGAATTCTTGCACCATTTCTGGAACATTCTAGCTCTGGGAGGTCACGTAACCTTCTTGGGGTAGTTCAGTGGTTTagtggtttataatccaggtgtgcgtcagaatcatctgaggaactttgctaaaatacaaaaatctggcctaagtagctccagatctacCTTCATAAAGGAATCTGACCACTCCTGGATTTGGTAATTTCCAAGTTCTGAAAATTTTACTTAGGATTTAATAACTATTAACATCTGTCCCTACATAGGTTTTCTTTCCTACTTATATACCTTATGTTCTCTTCATTCTAACCTTCATCAGTAATAGGGAAATGTTTTAATTTTATTTTTTTAGTTGAAGGGTAATGTACCAAAAAAtatagttcagtgaattaaaatgaacacacatgtgcaaccatcaattcaggtcaagaaatagaagattgtagcacacaaaagcctactcagccattctcccagtcactacttccttccTTACCCCTGGGTTATTTTTGAAATGACACTTGATGTATTTCCCTCTGTTGCTGTTATGAGAACATTGCTACAGCCAAGTGTTGTGTTTCTGTGTGCATAGGTTGATACTTAATTATCTCCCCACtttttaataaacttttaatttggaaataattttagattgacagaaaagttgcaaagatagtgaggaaagttcctgtctactctttgctcagcttcccttaatgttaacattttatatagcaagatgcatttgtcaaagctaacaagttaacattggtacaatcactgttaattaaactgcacacaatattcagatttcaccacttttccactaatattctttcattgttctaggattcaattcaggagaccacatttcatctagCCCTCTTTTTTAAAAGTAAATACTTTTCAGCACTTACAGGAGTTAACTGAGCTGGGGCATCATGGTGTATAGACGCCCTGACACTGGTCATCTTGGAATTCATTTAGTTTGTCAGTGGGTGCCCTGACATTCTGTCACAACATCAATTTGGGAACATGGCATTATATTTTTATCTTTGAACTTTTTTCTTTTTGGATGACATTTGATTAATGCGTCATCTTGGAACACATTATCTTTTTTCTTGGTTATGTGATCAGGAAGATTAATCAGTTTTTCCTGTTCTTGGTATAATTCCTGCTTTTCACATACCTGTCCCTTACAGTTCTCTATATATACCCTTCCCTTATTACACAGAGAGAAATATCTATCTATACTTTTTACACAAAATATACTTCAAAAGAAACAAAACAGCCACAATTATTAACTTTTTAAATAAATGAGAatttaattatatccta |