Summary

Gene Name	RBM8A
Specie	Homo sapiens
Full Name	RNA binding motif protein 8A
Also known as	BOV-1A|BOV-1B|BOV-1C|C1DELq21.1|DEL1q21.1|MDS014|RBM8|RBM8B|TAR|Y14|ZNRP|ZRNP1
Coordinate	chr1:145921556-145927484
Strand	-
Gene summary	This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]

Retrocopy(s) from RBM8A

Retroname	Coord	Strand	Genomic Region	ENSG
RBM8B	chr14:60397706-60400514	+	Intergenic	ENSG00000258427	UCSC

Expression

Transcript Sequences

>NM_005105.5

AGTTTCCCGAGGTACCTAGTGTCTGAGCGGCACAGACGAGATCTCGATCGAAGGCGAGATGGCGGACGTGCTAGATCTTCACGAGGCTGGGGGCGAAGATTTCGCCATGGATGAGGATGGGGACGAGAGCATTCACAAACTGAAAGAAAAAGCGAAGAAACGGAAGGGTCGCGGCTTTGGCTCCGAAGAGGGGTCCCGAGCGCGGATGCGTGAGGATTATGACAGCGTGGAGCAGGATGGCGATGAACCCGGACCACAACGCTCTGTTGAAGGCTGGATTCTCTTTGTAACTGGAGTCCATGAGGAAGCCACCGAAGAAGACATACACGACAAATTCGCAGAATATGGGGAAATTAAAAACATTCATCTCAACCTCGACAGGCGAACAGGATATCTGAAGGGGTATACTCTAGTTGAATATGAAACATACAAGGAAGCCCAGGCTGCTATGGAGGGACTCAATGGCCAGGATTTGATGGGACAGCCCATCAGCGTTGACTGGTGTTTTGTTCGGGGTCCACCAAAAGGCAAGAGGAGAGGTGGCCGAAGACGCAGCAGAAGTCCAGACCGGAGACGTCGCTGACAGGTCCTCTGTTGTCCAGGTGTTCTCTTCAAGATTCCATTTGACCATGCAGCCTTGGACAAATAGGACTGGGGTGGAACTTGCTGTGTTTATATTTAATCTCTTACCGTATATGCGTAGTATTTGAGTTGCGAATAAATGTTCCATTTTTGTTTTCTACATTTAATGTTACTTTCCTGTCCTAAAATTGAAAGTTCTAAAGCATAGCAAGGCTGTATGGATCATTGTGAAGATACTTCTAGGGACTGAACTCTATGTAtttcttttttttcttttttttgagatagagtcttgctgtgttacccagggtggattgcagctgatcatagctcactgcagcttcaaactcttgggctcaagccatccttctgcctcactgtccctagtagttgggattacaggcacatgccaccatgcccagctaaatttttaatatttttgtagagatggggtcttgctgtgttacctgggctagtTATGTGAGTTTCTATATTAGACATAGTCTCAAGTTTCAGGTAGGGTTTAAAGTAGAGACACTGGTCAGTATTTCTTTTTTGGGGGGAACTAGGAGAGCAGGAGTAGAAGTGAGATGTTAAGATCTTATGGCACTAAAGACTTACTATTCTGTTCCTACATACTCTGTTAGGATCAGATAGATGTTATAGAAATGCCTTTTGTTTCTCCTGCCCTTCTTGATGTCACAGTTTTTTGTACTTCCAGCTGTCTAAAGGCATGAATCTCCTCTTGGAGCATTCTCCCAGACCCTTCTTTAGAAGAGTCTATACTAAGTTCTTGGTGCCCTCTTCGGCAGCCAAGGGTGAAGGCCCCATAGAGGAGAGGATCCAAAGGAGCATTGAGGAGGCCCAAGAGGAAAAGGATGTGGCTCAGGCTGGGAGGGACTTCAGTTAGCATGGTGGGGGAGAACCAGTACCACATACCCAGTAGGTAATAAGGTGTCCAGCAGAGGATGAAGGTCAGCAAGATAAGCAGGGCCAGTCTCAGGGCCCGGAGACGAACACGGGGACAATTGTCAAAGGAGCGGGGGAGGGCAAATTCACCAGCAGGGGCTAGGAATTTAGAAAATATACTGTAATTCAGACACTCAGCTTCTGATCTGAGTATAGGGTGAATTGATGGAGGGGCATAGCTAGTGAGACAGAGCTCGCCTCCTACAAGGAGGAGAATGTTGCAAACCGTTTTCCCCTTCCCAACCTGGGACTATATGATTTCTTACCCCCAGGGATTATGATAGAAATATGAAGCCACCAAGTCTAGACTTGATGGTGTTCAAGAATAAATAATACTGATTGCCTCCCTAGTCCTTGTCCAGCTAACTCAGCTGTTTATAATTGAAGGGATTCAACAAAATTATCTCTAGCATCAGGTGCTAGACATGGTTAGAATCTCACCATGGTTTAGTGACTGGTAGATAGCTATTAGGTAGGTAGATAAATAAATGATGCTAGAGGCAACAGGTCTAGGGTTAAGGATTAAGGCCTGGGAATTGGAGTCTCACCATGGCTCCCCTTCCTTGTCTGGGGCCTGGACACACTGAGGACAATGCGGCTATAGCAGATGGCCATGGCAGTCAGTGGCAGCAGAAAGAGGCAGCAGAAGGTGAAGAGGTTATAGGTGGTCTCTTGCCATTGAGCCTTGAAGCTGCCTTTGGTGACACACTGAGTGAAAGGGACTGGGCCAGCTCAGTGGACCGTGTGGAACAGGAACAGCTGGAGTGGAGTTGAGGACTATTAGAACTGGTTCCCCTCACCACCCAACCTACCCACCTATGTCATACTGTCTCCTCCCAATTCATCCTTAATTCCAAGTGAAGCAGCACAGTGCTGAGAAACAGTTCATCCATGGTGCCATGTTAAAGAAGTTGGAAATATATCTTGAAAATCCTATCTTCCTTTTAGGCTTGAATATGATGCTGAACAGTAAGTTTGTTAAATCTTGGAACTTAAAACAATCCTGCTTTCTCAAGTACTATTCTAACATTGCGCTTTATAAGGGATGATATTTCTACCACCTCACTCATATTTTTAGCTGAAATGATTTTCCTGGTATGTCTGTTATTTTGTGGAAAAAGAAATATTGTGTAAAATGGGTGCTGCCAAAATTCCAGGCCATTTTGCAGGGACTCTGAAGTGACCTTTAGTAGTAATAGTCTTATGTGCAGTAACTATAATGGTAAAGAATGTTAAATAATAAAATTTAACATTTTCCAAATGCTATTGGGCTGCCCCTCCCCCTTTTTGTTAAATTGCTGGGTTTTCCAACTGAATCAGTAAAAACTATTTCTGTTTAGAGCTACAAGGTTAAAGTGCCTGCTTTCCAGTAATGGAGATTGAGTCACTATTAATTTGATAAAAGGTAAGCTCAGTAGGCATCAGATTCCTAGATACAAGGCATTTGGGAAAGTGATTTTAGCAGACATGAGGGACATTTAGGAAAGATGAATAGTTTCAGCCTAAGAGAATTTTGTGAACTGTTTGGAGTTACGATCAGGCTACTCTGAGCTAGTTGGGAAATGGTCTTTCCTCTTCCCATCTCTTGCATTCATATATTTCTAAGtttttttttttgtttttgtttttGTGCTCTGCCTAAGAAGTGCTTGAGAATTGTGAGGAGTATAAAAATAGTCAAAGCTggctgggcgcggtggctcacgcctgtaatcccagcactttgggaggctgaggcgggcggatcacgaggttaggagatggagaccatcctggctaacacagtgaaaccctgtctgtactaaagatacaaaaaactagccgggcgtggtggtaggtgcctgtagtcccagctacttgggaactcgggaggctgaggcaggagaatgacctgaacccaggaggcggagcttgcagtgagcagagattgcgccattgcactccagcctgggcgacagagtaagactgtctccaaaaaaaaaaaaaaTAATAATCAAAGCTCTTGGATTTATAGTTTGGTCCACAGCCTTGTTTTGATCTTTCCTTTATCCTGTTTTATTGCCATTTACCACGTACTGTAGAAACATCCCTTTCAACTGCTGATAACTTGGAAACAAGCCTACAAAAATAAGTAATTTCTAACTACTCCTAATACTACCTATAACTACCCCTAAGCCCTTACCACTCTAACGTGACATTATTAAATTTTTTATTTTATTAACACTAATATTTTAACTACAATTACAGCATATGGGCAATACAGAATTTACCTAAAAGGATACTAATTTGGAACAAAAAAAATCACCTTTCGCACATGTATCATGTCACAACCAGTTTGCCATTGAAACAAATagaggttgcaaatattgtcagattgtcaggctgtaagaaaggatgaaattcatttcccattgcatcatcttgtggcccatggatttcaagtgccttagccaaaatcatatagctagttagcagtagagccgagactcagaaAAAAACAAAGTAAAACAGGCAGACTGAAACAAAAAGTCTTCTAATTCCCAGTCCACATGTAAAATTTGCTTCATATAAACAAACCTAATTGTAAATGGCACTGTAGCAACAGGCTTCTTTTTAACACTTGGATTGGTAAAGGTCTTGTTTGCAACATATTAGAAGTATTATTTTTCTCTTTCCCCCCCACCCCACCCCCAacagagtctggctctgccgcccacgccggagtgcagtggtgcagtcttggctcactgcagcctccacttcccaggttcaagcaattctcgtgcctcagcctcctgagtagttgggattacaggtgctcaccactatacccggctaatttttgtatttttagtagagatggggtttcgtcatgttggccaggttggtcttaaactcctgacctcaagtgatccacccaccttggccttccaaaatgctgggattacaggcttgagccaccaggccTTTCTTTGTTCTTAGGAGTATAGTCAGACTAACTTCTAGTAGTTATATTTCTAATAATTGAGGATGTAAGTAAGGATCAAATCTTAAATCAGTATAATGCATTGTCATTCCAGAGATAAATCCTAGACCCTTCTTGGCCTCCTTCTGACATAATTCTAATCCTACAGTCTCAGAGATGCTGTTGTATCCTGCCCCCCAACCCCATGATAGTGATAGTGGTTTTTGCCTTGAAGGAATTGCTTTGTATTTAGCTTTTCCCCCTCTAGATTTCTAGTTCCTTTTCAGTATTGGATTGGATTTGAGATTTGATTAACCTAGTACTCAGGTTCAGATGCTCGCCTCTTTGCAATTTTAACACTCATTCGACAATAAAGTCAGTAAAAAACACAAA