| Gene Name | SELENOK |
|
| Specie | Macaca mulatta | |
| Full Name | N/A | |
| Also known as | SELK | |
| Coordinate | chr2:110076408-110083112 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER stress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Multiple pseudogenes of this locus have been identified. [provided by RefSeq, Sep 2017] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| SELENOKP5 | chr17:19408971-19409563 | - |
Intergenic |
ENSMMUG00000045155 | UCSC |
| SELENOKP1 | chr3:121294728-121295101 | + |
Intergenic |
N/A | UCSC |
| SELENOKP2 | chr4:22285279-22285487 | + |
Intergenic |
N/A | UCSC |
| SELENOKP3 | chr4:35377519-35378181 | - |
Intragenic |
N/A | UCSC |
| SELENOKP4 | chr10:68619992-68620665 | + |
Intergenic |
N/A | UCSC |
| SELENOKP6 | chr17:39326817-39327471 | - |
Intergenic |
N/A | UCSC |
| SELENOKP7 | chr19:10020380-10020672 | - |
Intergenic |
N/A | UCSC |
| SELENOKP8 | chr19:36936734-36937278 | - |
Intergenic |
N/A | UCSC |
| >NM_001159381.2 |
| CAGAGGCCGAGAGGGGCCAGGCGCCCGGTCGATCTGAAGCCGGGTAGTGGGAGAAGATGGTTTACATCTCGAACGGACAAGTGTTGGACAGCCGGAGTCAGTCTCCATGGAGATTATCTTTGATAACAGATTTCTTCTGGGGAATAGCTGAGTTTGTGGTTTTGTTTTTCAAAACTCTGCTTCAGCAAGATGTGAAAAAAAGAAGAAGCTATGGAAACTCATCTGATTCCAGATATGATGATGGAAGAGGGCCACCGGGAAACCCTCCCCGAAGAATGGGTAGAATCAATCATCTGCGTGGCCCTAGTCCTCCTCCAATGGCGGGTGGATGAGGAAGGTAAATGTCTGCTCTAAGAAGCAGACAACTGGACATGCACATTCACAGCAGAAGGAAACCATCAAGAAGTGGAAGGCCGACCATGCTGAGCCGTAGATGAATGTGTCTGTCTAAACAAGGACTGCTCTGTGTCCTCACAGATGAATGAGGTCATGCTAGGAATTCCCTCTACAGGGAACTGGCCTGACTGACATGCAGTTCCATAAATGCAGATGTTTGTCTCATGACCTTTTTGTATAGTTTATTAAAGTATTAATATAGTTTTAATAAGTAAATATTTTTAGGTTGCAGAGTGGACTCCTCATCTTTATATTCACGAAAAAACAATCTGAAGAAAATAAATAAAAGCCTGTGTATTTAGCA |