| Gene Name | LAMTOR3 |
|
| Specie | Homo sapiens | |
| Full Name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | |
| Also known as | MAP2K1IP1|MAPBP|MAPKSP1|MP1|PRO0633|Ragulator3 | |
| Coordinate | chr4:99878336-99894546 | |
| Strand | - | |
| Gene summary | This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| LAMTOR3P1 | chr13:36922442-36923682 | + |
Intergenic |
ENSG00000228825 | UCSC |
| LAMTOR3P3 | chr15:92627311-92627478 | + |
Intragenic |
ENSG00000259064 | UCSC |
| LAMTOR3P2 | chr5:119132131-119132917 | - |
Intragenic |
ENSG00000248979 | UCSC |
| >NM_021970.4 |
| ATGAATCATGTGACGGTGGCTTGAGGAGGAACCTGTCTTTAAAGCTGTCCCTGAAGTGACAGCGGAGAGAACCAGGCAGCCCAGAAACCCCAGGCGTGGAGATTGATCCTGCGAGAGAAGGGGGTTCATCATGGCGGATGACCTAAAGCGATTCTTGTATAAAAAGTTACCAAGTGTTGAAGGGCTCCATGCCATTGTTGTGTCAGATAGAGATGGAGTACCTGTTATTAAAGTGGCAAATGACAATGCTCCAGAGCATGCTTTGCGACCTGGTTTCTTATCCACTTTTGCCCTTGCAACAGACCAAGGAAGCAAACTTGGACTTTCCAAAAATAAAAGTATCATCTGTTACTATAACACCTACCAGGTGGTTCAATTTAATCGTTTACCTTTGGTGGTGAGTTTCATAGCCAGCAGCAGTGCCAATACAGGACTAATTGTCAGCCTAGAAAAGGAACTTGCTCCATTGTTTGAAGAACTGAGACAAGTTGTGGAAGTTTCTTAATCTGACAGTGGTTTCAGTGTGTACCTTATCTTCATTATAACAACACAATATCAATCCAGCAATCTTTAGACTACAATAATACTTTTATCCATGTGCTCAAGAAAGGGCCCCTTTTTCCAACTTATACTAAAGAGCTAGCATATAGATGTAATTTATAGATAGATCAGTTGCTATATTTTCTGGTGTAGGGTCTTTCTTATTTAGTGAGATCTAGGGATACCACAGAAATGGTTCAGTCTATCACAGCTCCCATGGAGTTAGTCTGGTCACCAGATATGGATGAGAGATTCTATTCAGTGGATCAGAATCAAACTGGTACATTGATCCACTTGAGCCGTTAAGTGCTGCCAATTGTACAATATGCCCAGGCTTGCAGAATAAAGCCAACTTTTTATTGTGAATAATAATAAGGACATATTTTTCTTCAGATTATGTTTTATTTCTTTGCATTGAGTGAGGAACATAAAATGGCTTGGTAAAAGTAATAAAATCAGTACAATCACTAACTTTCCTTTGTACATATTATTTTGCAGTATAGATGAATATTACTAATCAGTTTGATTATTCTCAGAGGGTGCTGCTCTTTAATGAAAATGAAAATTATAGCTAATGTTTTTTCCTCAAACTCTGCTTTCTGTAACCAATCAGTGTTTTAATGTTTGTGTGTTCTTCATAAAATTTAAATACAATTCGTTATTCTGTTTCCAATGTTAGTATGTATGTAAACATGATAGTACAGCCATTTTTTTCATATGTGAGTAAAAATAAAATAGTATTTTTAAAAATATAGTTTGAGCACTGTATAGGTCCTTTTTTTGTTCAGACTTTTTCCAAAAATCTAAACATAATTAATATACTCTTTCAGCCACATGAATAAATAATGAGTGTTTCTTGTAGGTATTGGTTTGGAGATTGTTTTACGGTAGTATGAACTGTTAACTGGAAAAGAAACCTgagattgcagtcagccaagattgtgccactgcaccccagcctgggcaacagagactccgtctcaaaaacaaaaaagaaaagaaaCCAAGAAACCTCAGGCATGAACCTAATTTAATCTCCATGAAAGAGGTACTACAGTTCTAGAATATACCCTTTATGTTCAGGAATGCAGTCTATCATTCAGAGTTAATTTCTTTCTAGGCTCTTTGACAATCAGTTTTTCCCTGGATCAGTTCAGTACATATGCATTGAGCACCTGTGTGCCAGTCAGCCGAGCTATCAcattgcacaattctaagaagcaccattcatgtctcatcatatttctatgctctgggagttgcctttcacatagaatatgtgtgattgttatccctagaattgtgcagtgAGGCAATTGGCTAGGTGCTGTGCTGCtttttctttctttctttttttttttaagagacagagtcttgctgtgttgcccagtctggagtgcagtggtggcatgatcttgcctcactgtaacctctgcctcctgggttcaagctgttctcatgccccattctcccttgtagctgggattacaggcttacaccatcgcacttggcaaatttgtgtatttttagtagagacaggaattcaccatgttggccaggctggtcttgaactcctgacttaaagtgatccacctgctttggcctcccaaaatgctaggattataggtgtgagccactgcaccgggccATGTGCTACTTtttcttccttccatccttcctcccttcttcAGTGTAAATATGAGATTAATTTGTGATACCTTACTTTAAAGAACTTAGAGTTCAGTAAAGGAAGCAGGTATAGAaagtgctatgataaagctatacataggatggtatagaaccacagactaggggcacttaaaatgggcAAGAAAATAGCCTTTGTAAATAAAATAGAGGCAAGAGATATAATGCTTTACCTGCAAAGAGCTATAAATAcagccatgtaccatataatgatgtttcagttagtgaaggaccacatacgagggtggtcagaacagcaggctataccatatagcctaggtgtgtagtaggctataccatatagcctaggtgtgtagtagtaggctataccatatagcctaggtgtgtagtagtaggcgataccatatagcctaggtgtgtagtagtaggctataccatatagcctaggtgtatagtagtaggctataccatatagcctaggtgtgtagtaggctataccatatagcctaggtatgtagtagtaggctataccatatagcctaggtgtgtagtagtaggctataccatctggggttcctgtcagtacagtatgatgttcacataatgatgaaatcacctaacaaagcatgtctcgaaatgtatccacattgttacgtaacacatgactgTAGTTAATTGTTACAATTGAAATACTAGATGTACTCATTGAAATCCAGAATTCCCATTATCTGGATtatttaatatcgttcaggaaatttttgccagtgcaatggtgcatgaaacaatgtcttttagaaatgaggtggccagatttctatttgcagataataattgtatatctaaaaatccTAGAAAAAGAAATGATAACAAATGGAGCTACTTAACCTTTACATGTTGAATGCTGCCACTGTTAAAATTTCTGAGGGGGTATAATAGATAAACTATCCCATAGTTCATCTGGAAAAATAAGGTGGTGAAAATTGCTAAGAAATTTTTGAAAGGGTAATGTAAACCTAGATTAACTGTTTTTGAAAGGTAGTACAGAACTGAATGCACAACTAGATATCAATGGTATGTACTCACCCAGAAAAAAGACTTCAGTACATACATGTGAGGGCTTAAAACATTGTTATAAAGACGGGATCACAATGGGAAAAGGATTATTCAATAAgtagggcaggcattctctatgcctgctagggaagtgtgacttgttatactctttatgtacagcaattggcagtctgtgaaacttttaaattcatatacataaccttttgccctgcaattccacttctagaaatttatcctaccaaacaaagcacatagatgtgcaaaagtatgtatttacaagtatattctttgcaacttggtaatgtcaaagaattggaagcaacctaaatatctgccataggtaggataaccatatgctttggctttttgaacactaccagtttatacctgctgttcttggataattattaatagtgctttcattctcaatgtctcactttagataataaattacaGAGGATTGGTGAAACTAATTTGCCCAATGGaaaaaggaatgaagaagtgctttaggtactgagatgaaaagatctctaaggcataataatgtttattgagaaaagcatggtgtcaaactgtatggcatgctacaattgatgtataagaagaaaaaatgtgtatgtattcctatttgtttgtatatggtagactgtctctgaagacatatatggaagaacctgatcacattggtagtctccaaggagcagaactagatacctgggggataaggatcccaggagtgagccttttcattgtaaacttcattgtactttgagtttttaacTGTTCAAAAATAATAAAATTAGAAATAAAATATTTCAACAAACAATAAAATGGGATATTTGGGGAAGAAAGTTGTCtcagggctctccaaagaagcagaa |