Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HMGB1P7
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species Rhinopithecus roxellana
Coordinates chr2:35295686-35296618  UCSC
Strand -
Parental Sequence XM_010367083.2
Parental seq. overlap 748 bp
Parental seq. overlap (%) 32%
Genomic Region Intergenic
Retrocopy Summary HMGB1P7, located on chr2:35295686-35296618, is a retrocopy of the parental gene HMGB1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HMGB1
Full Name N/A
Also known as HMGB1
Coordinate chr18:62044219-62051352
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens HMGB1P44
Chimpanzee Pan troglodytes HMGB1P17
Bonobo Pan paniscus HMGB1P17
Gorilla Gorilla gorilla HMGB1P16
Orangutan Pongo abelii HMGB1P16
Gibbon Nomascus leucogenys HMGB1P18
Green monkey Chlorocebus sabaeus LOC103214542P3
Crab-eating macaque Macaca fascicularis HMGB1P14
Rhesus Macaca mulatta HMGB1P16
Baboon Papio anubis HMGB1P10
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HMGB1P7
TTGCAGTACACTGAGCTCCACAGAGAGGGTGCTGGGGCAAGTGAGAGCCATATGGGCACTGGGCAACTCTGTGCCTTGTTGAAGAAAGATAACTAACATGGGCAAAGTAGATCCTAAGAAGCCAAGAGGCAAAATGTCATCATATGTGTTCTTTGTGCCAACTTGTCAGGAGGAGCACAAGGAGCACCCAGATGCCTCAGTCAGCTCCTCAGAGTTTTCTGAGAAGtgctcagagaggtgaaagacTACTTCTgctaaagcaaaaggaaaattggAAGACATGACAAAGGTGGGTAAAGCCCattatgaaagagaaatgaaaacttatacaTCTCTCCTAAAGGGGAGACAAAAAAGAAGTTCAAGGATCCCAATACACCCAAGAGGACTTCTTCAGCCCTTTTCTTATTCTGTTCTGAGTATCAcccaaaaatcaaagaagaacatCCTGGCCTAAACATTGGTGATGTTGCAAAGATGCTGGGAGAGATGTGGAATGGCACTGCTGAAGATGACTAGCAGCCCTATAAAAAGAATGCTGCAAAGTTcaaggaaaaatgtgaaaaggataCTGCTGCATACTGAACTAAAGGAAAGCCAGATGCAGCAAAAAGGGAGCTGTCAAggctgGTTAATGTTagcacaggtttttttttttttttcttgtctgtaaagcaTTTAACCTCCCTGTACACGATTcactccttttaaagaaaaaaattgaaatgtaagtttgtgtaagatttgtttttaaactgtacagtgtctttttttgtacagttaacacactACTAAATGTATCTTTAGATAGCCCTGTTCTGGTGGTAATTTCAGTGGGAACTAACCTTGCTTGGTACAGT
>XM_010367083.2
GCCAATAGGAGCCGCGCTGGCTGGAGAGTAATGTTACAGAGCGGAGAGAGTGAGGAGGCTGCGTCTGGCTCCCGCTCTCACAGCCATTGCAGTACATTGAGCTCCATAGAGACAGCGCCGGGGCAAGTAAGAGCCGGACGGGCACTGGGCGACTCTGTGCCTCGCTGAGGaaaaataactaaacatgggcaaaggagaTCCTAAGAAGCCGAGAGGCAAAATGTCATCATATGCATTTTTTGTGCAAACTTGTCGGGAGGAGCATAAGAAGAAGCACCCAGATGCTTCAGTCAACTTCTCAGAGTTTTCTAAGAAGTGCTCAGAGAGGTGGAAGacCATGTCtgctaaagagaaaggaaaatttgaagATATGGCAAAGGCCGACAAGGCCCgttatgaaagagaaatgaaaacctatatcCCTCCCAAAGGGGAGACAAAAAAGAAGTTCAAGGATCCCAATGCACCCAAGAGGCCTCCttcggCCTTCTTCCTGTTCTGCTCTGAGTATCGCCCAAAAATCAAAGGAGAACATCCTGGCCTGTCCATTGGTGATGTTGCGAAGAAACTGGGAGAGATGTGGAATAACACTGCTGCAGATGACAAGCAGCCTTATGAAAAGAAGGCTGCGAAGCTGAAGGAAAAATACGAAAAGGATATTGCTGCATATCGAGCTAAAGGAAAGCCTGATGCAGCAAAAAAGGGAGTTGTCAAGgctgaaaaaagcaagaaaaagaaggaagaggaggaagatgaggaagatgaagaggatgaggaggaggaggaagatgaagaagatgaagatgaagaagaagatgatgatgatgaataagTTGGTTCTAgcgcagtttttttttcttgtctataaagcaTTTAACCCCCCTGTACACAACTcactccttttaaagaaaaaaattgaaatgtaaggctgtgtaagatttgtttttaaactgtacAGTGTCTTTTTTTGTATAGTTAACACACTACCGAATGTGTCTTTAGATAGCCCTGTCCTGGTGGTATTTTCAATAGCCACTAACCTTGCCTGGTACAGTATGGGGGTTGTAAATTGGCATGGAAATTTAAAGCAGGTTCTTGTTGGTGCACAGCACAAATTAGTTATATATGGGGATGGTAGTTTTTTCATCTTCAGTTGTCTCTGATGCAGCTTATACGAAATAATTGTTGTTCTGTTAACTGAATACCACTctgtaattgcaaaaaaaaaaaaaaagttgcagctGTTTTGTTGACATTCTGGATGCTTCTAAGTAAATACAGTTTTTTTATTAGTATTGTTGTCCTTTTCATAGgtctgaaatttttcttcttgagGGGAAGCTAGTCTTTtgcttttgcccattttgaatCACATGAATTATTACAGTGTTGATCCTTTCATATAGTTAGCTAATAAAAAGCTTTTGTCTACACACCCTGCATACCGTAATGGGGGTAAAGTTAAGTTGAGATAGTTTTCATCCATAACTGAACATCAAAAGTCTTGATCAGTTAAGAAATTTCACATAGCCCACTTATATTTACAAACTGAAGAGTAATCAGTCTACTCAAAGCATGGGATTATTAGAATCAAACATTTTGAAAGTCTGTCCTTGAAGGACTAATAGAAAAGTATGTTCTAACCTTTACATGAGGACTCTATTCTTTAACTCCCATTACCATGTAATGGCAGTTATATTTTGCAGTTCCCACATTAAAGAAGACCCGAGAATGTATCCCCAAAAGCGTGAGCTTAAAATACAAGACTGCcatattaaattttttgttgacaTTAGTCTCAGTGAAGACTACGAAAATGCTGGCTATAGATGTCTTTTCCCATTTATCTCAATATGGACTGCTCAGGAAATGAGACTTTCCATtacaagtatttttaattaattgggccagcttttaaaatgaagatgcCACATTCAAAATAGGGTATATTTTCCTATATTATGGTTTGCCCCTTTATAAATCCAAGTAGGAGGAAAGAAGACACTTAAACTTTGCATCTCAGTATGaattattcaatttatttgaatgatttttctttacaaaaactcAGTCATTATCTGCTTAGCAGTTTAGGGAACAATTTGGCAATTTTGTGGTTTTCGAGATTATCGTTTTCTTAAAGtgccagtattttaaaatagcgTTCTTGTAATTTTACACGCTTTTGTGATGGAGTGCTGTTTTGTTATATAATTTTGACTTGGATTAtttccatttgcatttgtttatgtAATTTCAGGAAGAATACTGAACATCTGAGTCCTGGATGATACTAATAAACTAATAATTGCAGAGGTTTTAAATATTA

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