Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KARS1P2
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Rhinopithecus roxellana
Coordinates chr18:5868814-5869002  UCSC
Strand +
Parental Sequence XM_010382987.2
Parental seq. overlap 160 bp
Parental seq. overlap (%) 7.3%
Genomic Region Intragenic (F10)
Retrocopy Summary KARS1P2, located on chr18:5868814-5869002, is a retrocopy of the parental gene KARS1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KARS1
Full Name N/A
Also known as KARS1
Coordinate chr20:62526972-62546455
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens KARS1P2
Chimpanzee Pan troglodytes KARSP2
Bonobo Pan paniscus KARS1P2
Orangutan Pongo abelii KARSP2
Green monkey Chlorocebus sabaeus KARSP1
Crab-eating macaque Macaca fascicularis KARSP2
Rhesus Macaca mulatta KARSP2
Baboon Papio anubis KARS1P2
Dolphin Tursiops truncatus KARS1P1
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KARS1P2
ACCATGTTTCTCACAGACTCCCACAACATCATGGAAATATTTCTGCCTCCTGGCATGAAACTTGAAGACAAGAAAGAATGTAGCAACCACtaataaaatggaaacacaacattgACACTTCTTTCTAGAAAATGTTAATTGTCTAAGTTGTGTGACTCAGATATCTTTGCATTTCTGCAAAAGATCAAG
>XM_010382987.2
TGGAAATTAACGTACCATCCTCCTTACTTTTGGGTCGGGCCCTCCGGGAAGATGGCAGCGGTGCAGGCGGCAGAGGTGAAAGTGGATGGCAGCGAGCCGAAACTGAGCAAGAAGTGGTGGTAATCATTAGTTCCAGGGTGTTCTGCCATGTTGACGCAAGCTGCTGTAAGGCTTGTTAGGGGGTCCCTGCGCAAAACCTCCTGGGCAGAGTGGGGTCACAGGGAACTGCGACTGGGTCAACTTGCGCCTTTCACCGCACCTCACAAGGACAAGCCATTTTCTGATCAAAGAAGTGAGCTGAAGAGACGCCTGAAAGCTGAGAAGAAAGTAGCAGAGAAGGAGGCAAAGCAGAAAGAGCTCAGTGAGAAACAGCTAAGCCAAGCCACTGTGGCTGCCACCAGCCACACCACTGACAATGGTGTGGGTCCTGAGGAAGAGAGCCTGGACCCAAATcaataCTACAAAATCCGCAGTCAAGCAATTCATCAGTTGAAGGTCAATGGGGAAAATCCGTACCCACACAAGTTCCATGTTGACATCTCACTCACTGACTTCATCCAGAAATATAGTTATCTGCAGCCTGGGGATCACCTGACTGACATCACCTTAAAGGTGGCAGgtaGGATCCATGCCAAAAGAGCTTCTGGGGGAAAGCTCATCTTCTATGATCTTCGAGGAGAGGGAGTGAAATTGCAAGTCATGGCCAATTCCAGAAATTATAAATCAGAAGAAGAATTTATTCATATTAATAACAAACTGCGTCGGGGAGACATAATTGGAGTTCAGGGGAATCCTGGGAAAACCAAGAAGGGTGAGCTGAGCATTATTCCGTATGAGATCACACTGCTGTCTCCCTGTTTGCATATGTTACCTCATCTTCACTTTGGCCTCAAAGACAAGGAAACAAGGTATCGCCAGAGATACTTGGACTTGATCCTGAATGACTTCGTTAGGCAGAAATTTATCATCCGCTCTAAGATGATCACATACATAAGAAGTTTCCTGGATGAGCTGGGATTCCTAGAGATTGAAACTCCCATGATGAACATCATCCCAGGGGGAGCTATGGCCAAGCCTTTCATCACTTATCACAACGAGCTGGATATGAACTTATATATGAGAATTGCTCCAGAACTCTATCATAAGATGCTTGTGGTTGGTGGCATCGACCGGGTTTATGAAATTGGACGCCAGTTCCGGAATGAGGGGATTGATTTGACGCACAATCCTGAGTTCACCACCTGTGAGTTCTACATGGCCTATGCAGACTATCACGATGTCATGGAAATCACCGAGAAGATGGTTTCAGGGATGGTGAAGCATATTACAGGCAGTTACAAGGTCACCTACCACCCAGATGGCCCAGAGGGCCAAGCCTACGATATTGACTTCACCCCACCCTTCCGGCGAATCAACATGATAGAAGAGCTTGAGAAAGCCCTGGGGATGAAGCTGCCAGAAACTAACCTCTTTGAAACTGAAGAAACTCGCAAAATTCTTGATGATATCTGTGTGGCAAAAGCTGTTGAATGCCCTCCACCTCGGACCACAGCCAGGCTCCTGGACAAGCTTGTTGGGGAGTTCCTGGAAGTGACTTGCATCAATCCTACATTCATCTGTGATCACCCACAGATAATGAGCCCTTTGGCTAAATGGCACCGCTCTAAAGAGGGTCTGACTGAGCGCTTTGAACTATTTGTCATGAAGAAAGAGATATGCAATGCCTACACTGAGCTGAATGATCCCATGCGGCAGCGGCAGCTTTTTGAAGAACAGGCCAAGGCCAAGGCTGCAGGTGATGATGAGGCCATGTTCATAGATGAAAACTTCTGTACTGCCCTGGAATACGGGCTGCCCCCGACAGGTGGCTTTGGCATGGGCCTTGACCGAGTCGCCATGTTTCTCACGGACTCCAACAACATCAAGGAAGTACTTCTGTTTCCGGCCATGAAACCCGAAGACAAGAAAGAGAATGTAGCAACCACTGATACGCTGGAAAGCACAACAATTGGCACTTCTGTCTGAAAATGATAATTGCAAGTTGTATAACTCAGGCGTCTTTGCATTTCTGCGAAAGATCAAGTCTGCAAGAGAATTCTCGTGTGCTGCTTTCCATTTGACACCGCAGTTCGGTTCAGCCATTAGAAGAGAAACAaggaattaaaattttctttttaatccttgTTAC

Publications

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