Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Ctnnb1P1
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Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr7:97012616-97015387  UCSC
Strand +
Parental Sequence XM_008766691.2
Parental seq. overlap 2533 bp
Parental seq. overlap (%) 67.3%
Genomic Region Intergenic
Retrocopy Summary Ctnnb1P1, located on chr7:97012616-97015387, is a retrocopy of the parental gene Ctnnb1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Ctnnb1
Full Name catenin beta 1
Also known as Catnb
Coordinate chr8:129601511-129628378
Strand +
Gene summary Enables cadherin binding activity; ionotropic glutamate receptor binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including cellular response to insulin-like growth factor stimulus; cellular response to lithium ion; and cellular response to mechanical stimulus. Located in several cellular components, including dendritic shaft; intercalated disc; and nuclear membrane. Part of protein-containing complex. Colocalizes with neuron projection. Used to study colon adenocarcinoma and lung carcinoma. Biomarker of Alzheimer's disease and colorectal cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to human CTNNB1 (catenin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Ctnnb1P1
TGGTATCTGAAACTCAGCGAGCAACTGCTGTGACACTGTGGTTCGGACAATGGCTACTCAAGCTGAACGCATGGAGTTGGCCATGGAGCCAGACAGAAAAGCCTCTGTCAGCCATTGGCAGCAGCAGTCTTACCTGGACTCTGGAATCCACTCTGGTGCCACCACCTCAGCTCCTTCCCTGAGTGGCAAGGGCAATCCTGAGGAAGAAGCTGAAGACACCGCCCAAGTCCTTTGTGAGTGAGAACAAGGCTTTTCCCAGTTCTTTACACAAGAGCAAGCAGCTGACATTGATGGTCAGTACACTCAGGCTCTGAGGGTCCGAGCTACCATGTTCCCCGAGACACTAGATGAGGGCATGTAGATCCCATCCATGCAGTTTGACACTGCTCATCCCGCTAATGTCCAGTGCGTGGCTGAACCGTCACAGGTGCTGAAGCATGCAGTTGTCAATTTGATTAACTATCAGGATGACGAGGAAGTTGCCACACATGCAATTCCTGAGCTGACAAAACTGCTAAATGATGAGGCCCAGGTGGTCATTAATAAAGCTGCTTTTACGGTTCACCAGCTTTCCAAAAAGGAAGTTTCCAGACATGCCATCATGTGCTCTCCTCAGATGGTGTCTTCCATTGTGGTCACCATTCAGAATACAAATGATGTAGAAACAGCTCGTTGTACAGCTGGGACCTTACACAACCTTTCTCACCATCGAGTGGGTTTGTTGGCTATCTTTAAGTCTGGTGGCATCCCAGTGCTGGGAAAAATGCTTGGATCACCAGTGGATTCTGTACTGATCTATGCCATCACGACACTGCATAATTTCGTGCTACATCAGAAAGGAGCTAAAATGGCAATGTGCCTTAGCCGGTGGGCTGCAGAACGAACATGAAGTTCTTGTCTATTACGACAGACTGCCTTCAGGTCTTAGCTTACTGCAATCAGGAGAGCAAGCTGATCATCCTGGCTAGTGATGGACCTCAAGCCTTAGTAAACATAATGAGAACCTACACTTACGAGAAGCTCCTGAGGACCACAAGCAGAGCTCTGAAGGTGTTGTCTGTGTGCTGTAGCAACAAGTCGGCTATTGTGGAAGCTGGTGGGTTGCAGGCTCTGGGGCTTCACCTGACAGACCCAAGTCAGCAACCTTTCAGATGCAGCGACTAAGCAGGAAGGGATGGAAGGCCTCCTTGGGACTCTAGTGCAGCTTCTGGGGGCTCTTGGGCTCACTGTCCTTCATGCTGGTGACAGGAAGGACATTACCGAGCCTGCCATCTGTGCTCTTCGTCATCTGAGCAGCCGACATCAGGAAGCTGAGATGGCCCAGAATGCCACTCGCCTTCCTTATGGACTACCTGTTGCAGTTGAACTCCTGCACCCACCATCCCACTGGCCTCTGAGAAAGGCAACTGTTGGATTGATCCGAAACCTTGCCGTTTGCCCAGCAAATCATGCACCTTTGTGGGAACAGGGTGCTATTCCACGGCTAGTTCAGCTGCTTGTATGAGAGCATCAGGACATCCAACAGCGTACCTCCATGGTTGGAACACAGCAACAGTTTGTGGAGGGCGTCCGCATGGAGGAGATAGTTGAAGGGTGTACTGGAGTTCACCACATCCTCGCTCAGGATGTTCACAACCCGATCGTAATCCGAGGACTCAATATCATTCCCACTATTTGTGCAGTTGCTTTATTCTCCCATTGAAAATATCCAAAGAGTAGCTGCAGGGATCTTCTGTGAACTTGCTCAGGACAAAGAGGCTGCAGAGGCCATTGAGGCTGAGGGAGCCATTTCTCCACTCCAGGAACGAAGGCGTGACAACATATGCAGCTGCCGTTCTATTCCAACAAGCCACAGGACTACAAGAAATGGCTTTCAGTTAAGCTGACCAGTTCCCTCCTCAGGACAGAGCTAATGGCTTGGAATAAGACTGCTGATCTCAGACTGGACATTGGTGCCCAGAGAGAAGCCCTTGGATATCGTCAGGATGATCCCAGCTACTGTTCTTTTCACTCGGGTGGATATGGCCAGGACACGTTGGGGACAGACCTTATGATGGAGCATGAGATGGGTGGTCACCACCCTGTTGCTGACTATCCATTTGATGGGCTGCCTGACCTGGGACATGCACAGGACCTCATGGACAGGCTGTCCCCAGGTGATAGCAATCAGTTGGCCTGGTTTGATATTGATCTATAAATCATCCTTTAGGAGTAACCATACAAATGGATTTGGGGAGTGATTCAGGAAGTGAAAAATGCACACGAATAGATCACAAGATGGAGTAATCAAACTGTTTTTTTTTTTTTAATATCTGTACTGGTACTGACTTTGCTTGCTTTGAAGTAGCTTTTTTTTTCAGTAACTGTTAGTTTTTAAGTCTCGTTGTGTTATGTTCAAGTGAACCTGCTACAGCAATTTCTGGTTTCTAAGAACTGAGTAATGGTGTAGAATACTAATTCATAATCACAATAATTGTAATTTGGAGATGTGTAACATTGTGCAGCCTTTTATATAAATAGACAGATAGAAATTGCCCAATTAGTTTCCTTTTCATATACTTAAAATAAGCAGGTGGATCTATTTCCTGTTTTTAAACAAGAACATTATTGGGGATACGTGCAGTAGGGTAAATCAGTGAGAGGTGTTATCTGGGCCTTGTTTTGGACAGTATACCAGTTGCCTTTTATCCCAAAGTTGTTGTAACCTGCTATGATACAATGCTTCAACAGATAAGATTATAAAAATGGTTCAGAATTAAACTTTTAATTCAT
>XM_008766691.2
aaaaaaAAAAATAATAAGAGTCTGTTCACAGAGTACTAGAGGTCGTGAGCCTTAAGCTCCCATTTCATCCTTGGTAACTTAGTAGTGTTCTTGAATATTGTATAGTAAGGTCAAAGTGAAGACATAACTTAGGCTAACATTCGCCAGTGGAAGACGTCCCACTGTTGATGGCAGGGGCGTCTGTCTATACCAGCTGACGTGGCACGGACAACATTGTGCGAACTTAGGCAAACCTCATCACAAGGGACTTCCATTTGTACTTCAGACTTTGACTTAAAGATATTCTGCTTCTTCAATAAGCTGCATAAACCACCATTCTGATCTGGTAATTGTGCTATATCAGGAAAAACCGTGGGTTTATTTAATAAAAATTTGGTGGTTTTTCTTTAAAAAAAAAAAAATCTACTGCCTCCTGGCTGGGATTTCCAGGCATCCTGAACCCATGCACAGCCTTCAGGGTTGGTGGTGCAGCTGGATTTTAACTAGTGCTCTCTTGGCTTTCACTAGAGAGAGGCCATTCTCTAGCAGCACCTGTGTCCACACTCTGTTTCTGCTGAGAAGAGCCCAGTGGTGATGGAACTGTGGCTCGTCTGAATTTTCAGTGGATGCCATGATGAACTGACTTGGGTGAGGTGTGGGTGGGAGGAGCCAGAGCCTAAACAGGCAGCAGAATCACAGTGACAGGTTAAAAATCAAGCTTGACTTGTGACGACTTGAACTGTGACGACTTGAATTGTGATGACGGAATCTTTTCAGGGTATCTGAAGCTCAGCGCACAACTGCTGTGACACCGCTTTGTGGACAATGGCTACTCAAGCTGACCTCATGGAGTTGGACATGGCCATGGAGCCAGACAGAAAGGCCGCTGTCAGCCACTGGCAGCAGCAATCTTACCTGGATTCTGGAATCCACTCTGGTGCCACCACCACAGCTCCTTCCCTGAGTGGCAAGGGCAATCCTGAGGAAGAAGATGTGGACACCTCCCAAGTCCTTTATGAGTGGGAGCAAGGCTTTTCCCAGTCCTTCACGCAAGAGCAAGTAGCTGACATTGACGGTCAGTACGCCATGACTCGGGCTCAGAGGGTCCGAGCTGCCATGTTCCCTGAGACACTAGATGAGGGCATGCAGATCCCATCCACGCAGTTTGATGCCGCTCATCCCACTAATGTCCAGCGCTTGGCTGAACCGTCACAGATGCTGAAACATGCAGTTGTCAATTTGATTAACTATCAGGATGACGCGGAACTTGCCACCCGTGCAATTCCTGAGCTGACCAAACTGCTAAATGACGAGGACCAGGTGGTCGTTAATAAAGCTGCTGTTATGGTTCACCAGCTTTCCAAAAAGGAAGCTTCCAGACACGCCATCATGCGCTCCCCTCAGATGGTGTCTGCCATAGTGCGCACCATGCAGAATACAAATGACGTAGAAACAGCCCGTTGTACCGCTGGGACCCTACACAACCTTTCCCACCATCGAGAGGGCTTGTTGGCCATCTTTAAATCTGGCGGCATCCCAGCGCTGGTGAAAATGCTTGGGTCGCCAGTGGATTCCGTACTGTTCTACGCCATCACCACGCTGCATAATCTCCTGCTACATCAGGAAGGAGCTAAAATGGCAGTGCGCCTAGCTGGTGGGCTGCAGAAAATGGTTGCTTTGCTCAACAAAACAAACGTGAAGTTCTTGGCTATTACGACAGACTGCCTTCAGATCTTAGCTTACGGCAATCAGGAAAGCAAGCTCATCATTCTGGCCAGTGGTGGACCCCAAGCCTTAGTAAACATAATGAGAACCTACACGTACGAGAAGCTCCTGTGGACCACAAGCAGAGTGCTGAAGGTGCTGTCTGTCTGCTCTAGCAACAAGCCGGCCATCGTGGAAGCTGGTGGGATGCAGGCACTGGGGCTTCACCTGACAGACCCGAGTCAGCGACTTGTTCAAAACTGTCTTTGGACTCTGAGAAACTTGTCCGATGCAGCGACTAAGCAGGAAGGGATGGAAGGCCTCCTTGGGACTCTAGTGCAGCTTCTGGGTTCTGATGATATAAATGTGGTCACCTGCGCAGCTGGAATTCTCTCTAACCTCACTTGCAATAATTACAAAAACAAGATGATGGTGTGCCAAGTGGGTGGCATAGAGGCTCTTGTGCGCACTGTCCTTCGTGCTGGTGACAGGGAGGACATTACCGAGCCTGCCATCTGTGCTCTTCGTCATCTGACCAGCCGACATCAGGAAGCTGAGATGGCCCAGAATGCCGTTCGCCTTCATTATGGACTACCTGTTGTGGTTAAACTCCTGCACCCACCATCCCACTGGCCTCTGATAAAGGCAACTGTTGGATTGATCCGAAACCTTGCCCTTTGCCCAGCAAATCATGCGCCTTTGCGGGAACAGGGTGCGATCCCACGACTAGTTCAGCTGCTTGTACGAGCACATCAGGACACCCAGCGGCGCACGTCCATGGGTGGAACACAGCAGCAGTTCGTGGAGGGCGTCCGCATGGAGGAGATAGTTGAAGGGTGCACTGGGGCTCTCCACATCCTCGCTCGGGATGTTCACAACCGGATTGTGATCCGAGGACTCAATACCATTCCACTGTTTGTGCAGTTGCTTTATTCTCCCATTGAAAATATCCAAAGAGTAGCTGCAGGGGTCCTCTGTGAACTTGCTCAGGACAAGGAGGCTGCAGAGGCCATTGAGGCTGAGGGAGCCACAGCTCCCCTGACAGAGTTGCTCCACTCCAGGAATGAAGGCGTGGCAACATATGCGGCTGCTGTTCTATTCCGAATGTCTGAGGACAAGCCACAGGACTACAAGAAACGGCTTTCGGTTGAGCTGACCAGTTCCCTCTTCAGGACAGAGCCAATGGCTTGGAATGAGACTGCTGATCTCGGACTGGACATTGGTGCCCAGGGAGAAGCCCTTGGATATCGCCAGGACGATCCCAGCTACCGTTCTTTTCACTCTGGTGGATACGGCCAGGACGCCTTGGGGATGGACCCTATGATGGAGCATGAGATGGGTGGCCACCACCCTGGTGCTGACTATCCAGTTGATGGGCTGCCTGACCTGGGACACGCCCAGGACCTCATGGACGGGCTGCCTCCAGGTGATAGCAATCAGCTGGCCTGGTTTGATACTGACCTGTAAATCGTCCTTTAGGAGTAACCATACAAATGGATTTGGGGAGTGACTCACGCAGTGAAGAATGCACACGAATGGATCACAAGATGGCGTTATCAAACCCTAGCCTTGCTTGTTCCttttttttttttttttttttAATATCTGTAATGGTACTGACTTTGCTTGCTTTGAAGTAGCTTTTATTTTTTGCAGTAACTGTTAGTTTTTAAGTCTCGTAGTGTTATGTTCTAGTGAACCTGCTACAGCAATTTCTGATTTCTAAGAACTGAGTAATGGTGTAGAACACTAATTCATAATCACGCTAATTGTAATCTGGAGACGTGTAACATTGTGTAGCCTTTTGTATAAATAGACAGATAGAAATGGTCCGATTAGTTTCCTTTTTAATATGCTTAAAATAAGCAGGTGGATCTATTTCATGTTTTTGAACAAGAACTTTATTGGGGATACGTGCGGTGGGGTAAATCAGTAAGAGGTGTTACTTGAGCCTTCTTGTTTTGGACAGTATACCAGTTGCCTTTTCCCAAAGTTGTTGTAACCTGCCGTGATACAATGCTTCACCAGACGCGGTTATAAAAATGGTTCAGAATTAAACTTTTAATTCATTC

Publications

PMID - Link Title
No publications available for this retrocopy