Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Ddx3xP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr13:105408591-105410594  UCSC
Strand +
Parental Sequence XM_006256652.3
Parental seq. overlap 1771 bp
Parental seq. overlap (%) 38.1%
Genomic Region Intergenic
Retrocopy Summary Ddx3xP1, located on chr13:105408591-105410594, is a retrocopy of the parental gene Ddx3x. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Ddx3x
Full Name DEAD-box helicase 3, X-linked
Also known as -
Coordinate chrX:10400363-10414010
Strand -
Gene summary Predicted to enable several functions, including helicase activity; nucleic acid binding activity; and nucleoside-triphosphatase activity. Predicted to be involved in several processes, including positive regulation of type I interferon production; regulation of cellular protein metabolic process; and regulation of signal transduction. Predicted to act upstream of or within with a negative effect on primary miRNA processing. Predicted to be located in several cellular components, including centrosome; cytoplasmic stress granule; and nucleoplasm. Predicted to be part of NLRP3 inflammasome complex. Predicted to be active in P granule and nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to several human genes including DDX3X (DEAD-box helicase 3 X-linked). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Mouse Mus musculus Ddx3xP1
Chinese hamster Cricetulus griseus Ddx3x_1P1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Ddx3xP1
CGTACTCTTCAGGGATGAGTCATGTGGCAGAGGAAGATGAGCTTGGGCTGGACCAGCAGTTGGCTGGCCTAGACCTGACGTCTCCAGACAGCCAGAGCGGGGCAAGCACAGCCAGCAAAGGGCGCTACATCCCTCCTCACCTGCGGAACAGGGAGGCTACGAAAGCGTCCTACGACAAAGACAGCTCACGGTGGAGTAAAGACAAGGATGCCTACAGCAGCTTTGGTTCCCGCAGTGACACGAGAGCCAAGTCGAGTTTCTTCAGCGACCGCGGAAGTGGCTCCAGAGGAAGGTTTGATGACCGCGGGCGGAGTGACTATGAGGGCGTTGGCAGCCGTGGAGGTAGAAGTGGCTTTGGCAAATTTGAGCGGGGCGGGAACAGTCGCTGGTGTGACAAAGCAGACGAGGATGACTGGTCTAAACCACTCCCACCAAGCGAACGCTTGGAACAGGAGCTCTTTTCTGGAGGCAATACTGGGATTAACTTTGAGAAATATGATGACATTCCAGTTGAAGCGACAGGGAATAACTGCCCTCCACATATTGAAAGTTTCAGCGACGTCGAGATGGGAGAAATTATTATGGGAAACATCGAGCTCACTCGTTATACACGCCCAACTCCGGTACAAAAGCATGCTATTCCTATTATCAAGGAGAAAAGAGACTTGATGGCTTGTGCTCAAACAGGGTCTGGAAAAACGGCAGCTTTTCTTCTACCTATCTTGAGTCAGATCTATACAGATGGTCCAGGTGAGGCTTTGAGGGCCATGAAGGAGAATGGAAAGTATGGGCGTCGCAAACAGTATCCGATCTCCTTGGTTTTGGCTCCGACCAGAGAATTGGCAGTGCAGATCTATGAGGAGGCCAGGAAATTCTCATACCGATCTCGAGTTCGACCTTGTGTGGTTTATGGTGGAGCTGATATTGGGCAGCAGATTCGAGACTTGGAACGTGGCTGTCACTTGTTAGTAGCTACTCCAGGACGGCTAGTGGACATGATGGAGAGAGGAAAGATCGGACTGGACTTCTGCAAATACTTGGTGTTAGACGAAGCGGATCGAATGTTGGACATGGGCTTTGAGCCTCAGATACGAAGAATAGTTGAACAAGACACCATGCCTCCAAAAGGTGTCCGTCACACTATGATGTTTAGCGCTACTTTTCCTAAGGAAATACAGATGCTGGCTCGGGATTTCTTGGATGAATATATCTTTCTGGCCGTAGGAAGAGTCGGATCTACTTCTGAGAACATCACACAGAAAGTTGTGTGGGTGGAAGAAGCAGACAAGCGGTCATTTCTGCTTGACCTCCTGAATGCGACAGGCAAGGATTCCCTGATATTGGTGTTCGTGGAAACCAAAAAGGGTGCAGATTCTCTGGAGGATTTCTTATACCATGAAGGATATGCTTGTACCAGTATTCATGGAGACCGATCTCAGCGAGATAGGGAAGAGGCCCTTCACCAATTCCGATCAGGAAAAAGTCCAATTCTCGTGGCTACAGCAGTAGCAGCAAGAGGACTGGATATTTCCAATGTGAAACATGTCATCAATTTCGACTTGCCTAGTGACATCGAAGAATATGTGCATCGAATTGGCCGTACAGGTCGTGTTGGAAACCTTGGCCTTGCCACCTCATTCTTCAACGAGAGGAACATAAATATTACCAAAGATTTATTGGATCTTCTTGTTGAAGCAAAACAAGAAGTGCCATCTTGGCTAGAAAACATGGCTTTTGAACATCATTACAAGGGTGGCAGTCGTGGACGGTCCAAGAGCAGATTTAGTGGAGGATTTGGTGCTAGAGACTATCGACAAAGTAGCGGTGCCAGCAGTTCCAGCTTCAGCAGTGGCCGTGCTAGCAACAGTCGCAGTGGTGGAGGCAGCCATGGCAGCAGCAGAGGGTTTGGTGGAGGTAGCTATGGAGGCTTTTACAATAGTGATGGATATGGAGGAAATTATAGCTCCCAGGGGGTTGACTGGTGGGGTAACTGAGCCAGCTTTG
>XM_006256652.3
CGGTGCGCTTCAAAGCCGCAGTTCTCCCGTGAGAGGGTCTTTGCGGTAAAGCCAGCACTTGCTCAGCAGCGGAAGACTCCGAATTTTCGGTACTCTTCAGGGATGAGTCATGTGGCAGTGGAAAATGCGCTCGGGCTGGACCAGCAGTTTGCTGGCCTAGACCTGAACTCTTCAGATAATCAGACTGGAGGAAGTACAGCAAGCAAAGGGCGCTATATCCCTCCTCATTTAAGGAACAGAGAAGCTACTAAAGGATTCTATGACAAAGACAGTTCAGGGTGGAGTTCTAGTAAAGATAAAGATGCATACAGCAGCTTTGGATCCCGGGGTGACTCACGAGGGAAGTCTAGCTTCTTTGGTGATCGTGGAAGTGGATCAAGGGGAAGGTTTGATGATCGTGGACGGGGAGACTATGATGGCATTGGTGGCCGTGGAGATAGGAGTGGCTTTGGCAAATTTGAAAGAGGTGGAAATAGTCGCTGGTGTGATAAATCAGATGAAGATGACTGGTCAAAGCCACTCCCACCAAGTGAACGCTTGGAACAGGAACTCTTTTCTGGAGGCAATACTGGGATTAACTTTGAGAAATATGATGACATTCCAGTTGAAGCAACAGGCAACAACTGTCCTCCACATATTGAAAGTTTCAGTGATGTTGAGATGGGAGAAATTATTATGGGAAACATTGAGCTTACTCGTTATACTCGTCCAACTCCAGTGCAGAAGCATGCTATTCCTATTATCAAAGAGAAAAGAGACTTGATGGCTTGTGCTCAAACAGGCTCTGGAAAAACTGCAGCATTTCTCTTGCCCATCTTGAGTCAGATTTATGCTGATGGTCCCGGAGAGGCTCTGAGGGCCATGAAGGAAAATGGAAGATATGGGCGTCGTAAACAGTATCCAATCTCCTTGGTACTGGCACCAACGAGAGAATTGGCAGTGCAGATCTATGAGGAAGCCAGAAAATTCTCATACCGGTCTAGAGTCCGTCCTTGCGTGGTTTATGGTGGTGCTGAAATTGGTCAGCAGATTCGAGACTTAGAACGTGGATGCCACTTGTTAGTAGCCACTCCAGGACGTCTAGTGGACATGATGGAGAGAGGGAAGATCGGGCTAGACTTCTGCAAATACCTGGTGTTAGATGAAGCTGACCGGATGTTAGATATGGGGTTTGAACCTCAGATACGTAGAATAGTTGAACAAGACACTATGCCTCCAAAAGGTGTCCGCCACACTATGATGTTTAGTGCTACTTTTCCTAAGGAAATACAGATGCTGGCCCGTGATTTCTTAGATGAGTACATATTTCTGGCTGTAGGAAGAGTTGGGTCTACTTCAGAGAACATCACACAAAAAGTGGTTTGGGTGGAGGAGATAGACAAAAGATCATTTCTGCTTGACCTCCTAAATGCAACAGGCAAGGATTCCCTGACTCTAGTGTTTGTGGAGACCAAAAAGGGTGCAGATTCGCTGGAGGATTTCTTATACCATGAAGGATATGCCTGTACCAGTATCCATGGAGACCGTTCTCAGAGAGATAGGGAAGAGGCCCTTCACCAGTTCCGCTCAGGAAAAAGCCCAATTCTAGTAGCTACAGCAGTAGCAGCAAGAGGACTGGATATTTCAAATGTGAAGCATGTTATTAATTTTGACCTGCCTAGTGATATCGAAGAATATGTGCATCGCATAGGCCGTACAGGGCGTGTAGGAAACCTTGGTCTTGCCACCTCATTCTTTAATGAAAGAAATATAAATATTACTAAGGATTTACTGGATCTTCTTGTTGAAGCAAAACAAGAAGTGCCATCTTGGTTGGAAAACATGGCTTTTGAACACCACTATAAGGGTAGCAGCCGTGGACGTTCTAAGAGCAGTCGATTTAGTGGAGGGTTTGGTGCCAGAGACTATCGAcagagtagcggcgccagcagttccagcttcagcagcagccgcgcaagcagcagcCGGAGTGGTGGAGGTGGCCATGGCAGCAGCAGAGGATTTGGTGGAGGTGGCTATGGAGGCTTTTACAACAGTGATGGATACGGAGGAAATTACAACTCCCAGGGGGTTGACTGGTGGGGAAACTGAGCCTGCTTTGTAGTAGGTCACCCTGCCAAACAAGCTAATATGGAAACCACATGTAACTTAGCCAGACTATACCTTGTGTAGCTTCAAGAACTCGCAGTACATTACCAGCTGTGATTCTCCACTGAAATTTTTTTTTTTTTAAGGGAGCTCAAGGTCACAAGTAAAGATGAAAGGAACAATCAGCAGCCCTGTTCTGAAGGTGGTTTGAAGACTTCATTGCTGTAGTTTGGATTAACTCCCCTCCCGCCTACCCCTATCCCAAACTGCATTTATAATTTTGTGACTGAGGATCATTTGTTTGTTAATGTACTGTGCCTTTAACTTTAGACAACTTTTTATTTTGATGTCCTGTTGGCTCAGTAATGCTCAAGATTCCAATTGTTTTTGACAAAATAAATTTACTGAACTTGGGCTAAAATCAAACCTTGGCACACAGGTGTGATACAACTTAACAGGAATCATCGATTCATCCATAACTAATATAAGGAAAAACTCAAGTGGTAGCCTGCCTAAGGGCTTTTGATACTTGCAGATTGGGGAAATCAAACAACAAACGTCTTGAAGCATATTAATGGAATTAGTTTCTAATGTGGCAAACTGTATTAAGTTAAAGTTCTGATTTGCTCACTCTATCCTGGATAGGTATTTAGAACCTGATAATAGTCTTTAAACAAGCCATTCCAGTCATGATGAGGTGATGTATGAATACATGCATACATTCAAAGCACTGTTCTCAAAGTTAATGCAAGTAAATACAGCAATTCCTCTTTCAATGTTTAGGCAGATCGTTAACTATGAGCTAGCCAAATGTGGGCATGTTATTACAGGGAAAGTTTAAAGGTCTGATAACTTGAAATAGGTTTTTAGGAGAATTCATCTACTTAGACTTTTTAAATGCCTGCCATACAAGAAATTGAAATGGTAGAATGGCTGACCACAGCAATGACCAGCCCTCACTCAGGGCTCTGGATGATTTTTTGGTCTAATAACGCATGCTAGTGTTGATGTTTTTTGGTCAAGATGGGGATGAACAGGAAGAATTATGCAGCAGGCTTTATTTTAAATGCCGATTCACATTACTCTGTTCAAGCTGCGTTGAGATGTTAAACTGGCTTACTATAGACTTTGTAAAAAACAAAAACAAATGGCTCCAGAAGAATACCAAACTGAAATCTGAGATCACACAGGTTGGAAATATGTACATAACTGCACAAGGTGTCAGTTCTGCTCTACAGTGCAGTTTAGTCAGTTTTAGTTGCATAGGTTTCCATTGTATTTATAGTCTGTTTATGCTAAATCTGGCCAAAGATGAGCATTGTCCACCACTAAAATGCCTATGCCACTTGGAATTCTGGGCTAATTTTGTGACCAGAATGCAGTGATCAAAACGCTCAATCTTTTTACAGTGGCATAGGAAGACGGCAAAAATTTCCTAAAGTGCAATAGATTTTCAAGTGTATTGTGCCTTGTTCTAAAACTTTTATTAAGTAGGTGCACTTGACAGTATTGAGGTCATTTGTTATGGTGCTATTTCAATTAGTCTAGGTTTAGGCCCTTGTACATTTTGCCCATAACTTTTTACAAAGTACTTCTTTTATTGCACATTCAGAGAATTTTATATATATGTCTTGTGTGCGTGTCCTTAAACTTCCAATCTTATTTTGTCTCTTGGAGATTGTTGAACGCAGCTTGTCTAGGAAAGGGATGGGACTAGATTCTAAAATTTATTTGGGACCATGGGAATGATAGTTGGGAAGAAAACTTTGCACACGACAGATTTCTAGATACTTTTTGCTGCTAGTTTTATGTAATATTTATTGAACATTTTGACAAATATTTATTTTTGTAAGCCTAAAAGTGATTCTTTGAAAGTTTAAAGAAACTTGACCAAAAGACAGTACAAAAACACTGGCACTTGAATGTTGAATGTCACCGTATGCGTGAAATTATATATTTCGGGGTAGTGTGAGCTTTTAATGTTAAGTCATAATAAACTCTTAAGTCAAATTAAGCAGACCCGGCATTGGCGGTGTAGCCATAACTTTCTGATGTTAGTAAAAACAAAATTGGCGACTTGAAACTAAATCATGCCAAGGTTTTGATACACTTGTCTTAAGATATTAATGAAACACTTCAAAAACACTGATACAAAGTGTCCAGATTCTCAGATGTTTGTTGTGTGAGTTTTGTTTAGTTGTATTTTTTTTCAGTGAATGTCTGGCACATTGCAATCCTCAAACATGTGGTTATCTTTGTTGTATTGGCATATTCAGTGACTTGGACATTCAGCGATAGCATTGGAGCAAGTCTTATCAGCAAGCAATGTTTTCAGTTATGTTTCAAAGTTAAGAATGGGTTTAAACTTGCTGAACGTAAAGATTGACCCTCAAGTCACTGTAGCTTTAGTACTTGCTTATTGTATTAGTTTAGATGCTAGCACCGCATGTGCTCTGCATATTCTGGTTTTATTAAAATAAAAAGTTGAACTGCACAGTCTCCTTTGTTGTTGTCAATTGTGGTTTACTTTTAGAGGTGAAAATAAAGTTGTGCTCTTGCCTGAA

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