Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name Dnmt3aP2
Wait
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr8:17367568-17370093  UCSC
Strand -
Parental Sequence NM_001003957.1
Parental seq. overlap 2326 bp
Parental seq. overlap (%) 66.5%
Genomic Region Intergenic
Retrocopy Summary Dnmt3aP2, located on chr8:17367568-17370093, is a retrocopy of the parental gene Dnmt3a. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Dnmt3a
Full Name DNA methyltransferase 3 alpha
Also known as -
Coordinate chr6:28205375-28346052
Strand +
Gene summary Enables chromatin binding activity. Involved in several processes, including cellular response to ethanol; hepatocyte apoptotic process; and response to vitamin A. Located in cytoplasm and nucleus. Used to study lung carcinoma and middle cerebral artery infarction. Biomarker of congenital heart disease; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia; acute lymphoblastic leukemia; acute myeloid leukemia; myelodysplastic syndrome; and stomach cancer. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

OvaryBrainHeartLiverTestisKidney00.050.10.150.2
log10(TPM+1)

Related Sequence

>Dnmt3aP2
CTTCATTGGTGGAATGTGCCAGAACTGTAAGAACTGCTTCTTGGAGTGTGCTTGCCAATACGATGACGACGGGTACCAGTCCTACTGTACCATCTGCTGTGGGGGGCACGAAGTGCTCATGTGTGGGAACAGCAACTGCTTCAGGTGCTTTTGTGTGGAGTGTGTGGATCTCTTGGTGGGGCCAGGGGCTGCCCAAGCAGCCATTAAGGAAGACCCCTGGAACTGCTACATGTGTGGGCACAAGGGCACGTATGGGCTGCTGCAGAGACGGGAGGACTGGCCTTCTCGACTCCAGATGTTCTTCGCCAATAACCACGACCAGGAATTTGACCCCCTGAAGGTTTACCCACCTGTGCCAGCTGAGAAGAGGAAGCCCATCCAGGTGCTATCTCTCTTTGATGGGATTGCTATAGGGCTCCTGGTGCTGAAGGACCTGGGCATTCAAGTGGACCGCTACATCGCCTCCGAGGTGTGCGAGGACTCCATCACAGTGGGCATGGTGCAGCACCAGGGAAAGATCATGTACGTCGGGGACGTACGCAGCGTCACATAGAAGCTTATCCAGGAGTGAGGCCCATTTGATCTGGTGATTGGGGGCAGTCCCTTCAATGACCTCTCCATCGTCAACCCTGGCCGCAAGGGACTTCACGAGGGCCCTGGCCACCTCTTCTTTGAGTTCTACCGCCTCCTGCATGATGCGCGGCCCAAGGAGGGAGATGATCGCCCCTTCTACTGGCCCTTTGAGAATGTGGTGGCCATGGGCGTTAGTGACAAGAGGGACATCTTGCGATTTCTTGAGTCTAACCCCGTGATGATTGACGCCAAAGAAGTGTCTGCTGCACACAGGGCCCATTACTTCTGGGGTAACCTTCCTGGCATGAACAGGCCATTGACATCCACTGTGAATGATAAGCTGGAGCTGCAGGAGTGTCTGGAACACGGTCAAGTTCAGCAAAATGAGGACCATTACCACCAGGTCAAACTCCATAAAGGAGGGCAAAGACCAGCATTTCCCTGTCTTCATGAATGAGAAGGAAGACATCCTCTGGTGCACTGAAATGGAAAGGGTGTTTGTCTTCCCTGTCCACTACACAGACGTCTCCAACATGAGCCGCTTGGTGAGGCAGAGACTGCTGGGCTGATCGTGCCAGTCATCCTCCACCTCTTCGCTCTGCTGAAGGAATATTTTGCTTGTGTGTAAGGGACATGGGGGCAAACTGAAGTAGTGATGATAACCAACTTaCCAAGAACGAGAGGAAGGAGAGAAGTTCAGCACCCAGAAGAGAAAAAGGAATTTAAAGCAAACCACAGAGGAGGAAATGCCGGAGGGCTTGGCCTTGCCAAAGCGTTGGACATCATCTCTTGAGTTTTCATCTTCAGTCCTAACTAAAAAGCAGGATAGGCCCCTCCCCTTCCTCCCCTCCGGTCCTAGGAGGCAAACCTTTTGCTTTCTACTCTTTTATTCAGAGGGGTTTTCTGTTTGTTTGGGTTTTTGTTTCTTGCTGTGACTGAAACAAGAGAGTTAATTGCTGCAAAATCAGTAACAACAAAAAGTAGTAATGCCTTGGAGAGGAAAGGGAGAGAGGGAAAATTCTATAAAAACTTAAAGTATTGTTTTTTTTCCTTTTCTATATATCTCTTTGGTTGTCTCTAGCCTGATCAGATAGGAGCACAAACAGGAACAGAATAAAGACCCCCGGAGGCAGAGTCTCCTCTCGCAGCCCCTGAGCGGTCTCAACAGCACCATCCCTGGTCATGCAGAACAGAACCCAACTAGCAGCAGGGTGCTGTGAACACCACACCAGACACTTTTCTACAGTATTTCAGGTGCCTACCACACAGGAAACCTTGAAGAAAACCAGTTTCTAGAAACCGCTGTTACCTCTTGTTTACAGTTTATATATATACGGTAGATATGATATATATAAAAGGTACTGTTAACTACTGTACATCCCAACTTCATAATGGTGCTTTCAAAGCAGCGAGATGAGCGAAAACATCAACCTCCACCTGGCCCTCTGTGCAAAGGATTTCAGCCCAGGATGGGGAGGGAAGCAGCTAGAGGGTGTCggtCCCTCTTGGTTTTTAACAAACCAAAGGAGGAACCATATTGCCCCCACCCCCACTCCACCCCATGCCTAGCTTCTCCTCCCAAAAGCAAAGCACAGCTGAGGTGGTCAGAACCTGGGGAAGCGGAGTGTGGAATTTATCCAGACTCGCTTGCAATAACCTTTGAATATGAATCTAAAAAGGCTGCCTCAGAAAAATGGCTTAAAAAAAAAAAAACCAAACTTTGTCCCCGATTTTGAATCTGTCAGCCACATTGAAGGCCCCCTCGTGGGATAAGAAATAATCCAGAGTGAGGGAAAGTGACCCACCATTAACCCCACCTGGAGTAAATAAAAACATACAAAACA
>NM_001003957.1
CGCCCCCAGCCCCAACGCCCCCTGCCCCTCCCCCCAGACGGGCAGCTATTTACAGAGCTTCGGGCCGGGGCTCACACCTGAGCTGTACTGCAGAGGGGCTGCACCTGGCCTTATGGGCTGAGAAGAAAGCCAAGGTGATTGCAGTAATGAATGCTGTGGAGGAAAGCCAGGCCTCTGGGGAGTCCCAGAAGGTGGAGGAGGCCAGCCCTCCTGCAGTGCAGCAGCCCACGGACCCTGCATCTCCCACTGTGGCCACCACCCCTGAGCCAGTAGGGGCTGATGCTGGGGACAAGAATGCTACCAAGGCAGCTGATGACGAGCCCGAGTATGAGGATGGCCGGGGCTTTGGCATTGGAGAGCTGGTGTGGGGGAAACTCCGGGGCTTCTCCTGGTGGCCAGGCCGAATTGTGTCTTGGTGGATGACAGGCCGGAGCCGAGCAGCCGAAGGCACTCGCTGGGTCATGTGGTTCGGAGATGGCAAATTCTCAGTGGTGTGTGTCGAGAAGCTCATGCCCCTGAGCTCCTTCTGCAGTGCGTTCCACCAGGCCACCTACAACAAGCAGCCCATGTACCGCAAAGCCATCTACGAAGTCCTCCAGGTGGCCAGCAGCCGTGCAGGGAAGCTGTTCCCAGCATGTCATGACAGCGATGAAAGTGACACTGGCAAGGCTGTGGAGGTGCAGAACAAGCAGATGATTGAGTGGGCCCTTGGCGGCTTCCAGCCCTCTGGTCCCAAAGGCCTGGAGCCACCAGAAGAGGAGAAGAATCCTTACAAGGAAGTTTACACCGACATGTGGGTGGAGCCTGAGGCAGCTGCTTATGCCCCACCCCCACCAGCCAAGAAACCCAGAAAGAGCACAACAGAGAAACCCAAGGTCAAGGAGATCATTGATGAACGCACAAGAGAACGGCTCGTGTATGAGGTGCGCCAGAAGTGCCGAAACATCGAGGACATTTGTATCTCATGTGGGAGCCTCAATGTTACCCTGGAGCACCCACTCTTCATTGGTGGAATGTGCCAGAACTGTAAGAACTGCTTCTTGGAGTGTGCTTACCAATACGATGACGATGGGTACCAGTCCTACTGTACCATCTGCTGTGGGGGGCGCGAAGTGCTCATGTGTGGGAACAACAACTGCTGCAGGTGCTTTTGTGTGGAGTGTGTGGATCTCTTGGTGGGGCCAGGGGCTGCCCAAGCAGCCATTAAGGAAGACCCCTGGAACTGCTACATGTGTGGGCACAAGGGCACGTATGGGCTGCTGCGGAGACGGGAGGACTGGCCTTCTCGACTCCAGATGTTCTTCGCCAATAACCACGACCAGGAATTTGACCCCCCGAAGGTTTACCCACCTGTGCCAGCTGAGAAGAGGAAGCCCATCCGGGTGCTATCTCTCTTTGATGGGATTGCTACAGGGCTCCTGGTGCTGAAGGACCTGGGCATCCAAGTGGACCGCTACATCGCCTCCGAGGTGTGCGAGGACTCCATCACAGTGGGCATGGTGCGGCACCAGGGAAAGATCATGTACGTCGGGGACGTCCGCAGCGTCACACAGAAGCATATCCAGGAGTGGGGCCCATTCGATCTGGTGATTGGGGGCAGTCCCTGCAATGACCTCTCCATCGTCAACCCTGCCCGCAAGGGACTTTACGAGGGCACGGGCCGCCTCTTCTTTGAGTTCTACCGCCTCCTGCATGACGCGCGGCCCAAGGAGGGAGATGATCGCCCCTTCTTCTGGCTTTTTGAGAATGTGGTGGCCATGGGCGTTAGTGACAAGAGGGACATCTCGAGATTTCTTGAGTCTAACCCCGTGATGATCGACGCCAAAGAAGTGTCTGCTGCACACAGGGCCCGTTATTTCTGGGGTAACCTTCCTGGCATGAACAGGCCATTGGCATCCACTGTGAATGATAAGCTGGAGTTGCAAGAGTGTCTGGAACACGGCAGAATAGCCAAGTTCAGCAAAGTGAGGACCATTACCACCAGGTCAAACTCCATAAAGCAGGGCAAAGACCAGCATTTCCCTGTCTTCATGAATGAGAAGGAAGACATCCTCTGGTGCACTGAAATGGAAAGGGTGTTTGGCTTCCCTGTCCACTACACAGACGTCTCCAACATGAGCCGCTTGGCGAGGCAGAGACTGCTGGGCCGATCGTGGAGCGTGCCAGTCATCCGCCACCTCTTCGCTCCGCTGAAGGAATATTTTGCTTGTGTGTAAGGGACATGGGGGCAAACTGAAGTAGTGATGATAACCAAGTTAAACAAACAAAAAAACAAAACACAATAAAACACCAAGAACGAGAGGACGGAGAGAAGTTCAGCACCCAGAAGAGAAAAAGGAATTTAAAGCAAACCACAGAGGAGGAAATGCCGGAGGGCTTGGCCTTGCAGAAGGGTTGGACATCATCTCTTGAGTTTTCAATGTTCATCTTCAGTCCTAACTAAAACGCAGGATAGGCCCCTCCCCTTCCTCCCCTCCGGTCCTAGGAGGCGAACCTTTTGTTTTCTACTCTTTTTTTCAGAGGGGTTTTCTGTTTGTTTGGGTTTTTGTTTCTTGCTGTGACTGAAACAAGAGAGTTAATTGCAGCAAAATCAGTAACAACAAAAAGTAATGCCTTGGAGAGGAAAGGGAGAGAGGGAAAATTCTATAAAAACTTAAAATATTGTTTTTTTTTTTTCCTTTTCTATATATCTCTTTGGTTGTCTCTAGCCTGATCAGATAGGAGCACAAACAGGAACAGAATAGAGACCCTCGGAGGCAGAGTCTCCTCTCGCAGCCCCCGAGCGGTCTCAACAGCACCATCCCTGGTCATGCAGAACAGAACCCAACTAGCAGCAGGGCGCTGAGAATACCACACCAGACACTTTTCTACAGTATTTCAGGTGCCTACCACACAGGAAACCTTGAAGAAAACCAGTTTCTAGAAGCCGCTGTTACCTCTTGTTTACAGTTtatatatatacgatagatatgagatatatatataAAAGGTACTGTTAACTACTGTACATCCCAACTTCATAATGGTGCTTTCAAAACAGCGAGATGAGCAAAAACATCAACCTCCACCTGGCCCTCTGTGCAAAGGGTTTCAGCCCAGGATGGGGGAGGGAAGCAGCTAGAGGGTGTCGttttttttttttttttttGTCCCTCTTGGTTTTTAACAAACCAAAGGAGGAACCATATTGCCCCCACCCCCACCCCACCCCATGCCTAGCTTCTCCTGCCAAAAGTGGGGCTCAGCTGAGGTGGTCGGAACCTGGGGAAGCGGAGTGTGGAATTTATCCAGACTCGCGTGCAATAACCTTTGAATATGAATCTAAAACGACTGCCTCAGAAAAATGGCTTAAAAAAAAAAAAAGTTGTCCCTGATTTTGAATCTGTCAGCCACATTGAAGGCCCCCTTGTGGGATAAGAAATAATCCAGAGTGAGGGAAAGTGATCCGCCATTAACCCCACCTGGAGCAAATAAAAAAACATACAAAACGT

Publications

PMID - Link Title
No publications available for this retrocopy